Scientific Rationale for a Bottom-Up Approach to Target the Host Response in Order to Try and Reduce the Numbers Presenting With Adult Respiratory Distress Syndrome Associated With COVID-19. Is There a Role for Statins and COX-2 Inhibitors in the Prevention and Early Treatment of the Disease?Immunology Published on 2020-09-022022-10-31 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Anti-inflammatory anti-inflammatory properties ARDS Course COVID-19 COVID-19 pathogenesis COX-2 inhibitors diabete Diclofenac Effectiveness High dose host response hypertension immunomodulatory Inflammatory response inhibitor Intervention medication medications Mortality number pandemic post infection prevention pro-inflammatory rationale reduce respiratory response role smoking statin statins subsequent Symptom target the disease therapeutic Toxicity Treatment virus [DOI] 10.3389/fimmu.2020.02167 PMC 바로가기 [Article Type] Immunology
Pros and cons for use of statins in people with coronavirus disease-19 (COVID-19)Article Published on 2020-07-112023-07-02 Journal: Diabetes & metabolic syndrome [Category] SARS, [키워드] Coronavirus disease-19 (COVID-19) Diabetes Mellitus oxidative stress Severe acute respiratory syndrome-coronavirus2 (SARS-CoV2) statins [DOI] 10.1016/j.dsx.2020.07.011 PMC 바로가기 [Article Type] Article
Cholesterol-modifying drugs in COVID-19Short Communication Published on 2020-06-182022-10-29 Journal: Oxford Open Immunology [Category] COVID-19, [키워드] Alter anti-inflammatory effect Antiviral cardiovascular disease cholesterol cholesterol-modifying drugs coronavirus COVID-19 drug dyslipidaemia dyslipidemia Effect highlight Immune cell Immunity immunomodulatory in vitro in vivo models Inflammation management mechanism membranes obesity outcome pleiotropic promote protective immunity Replication resulting SARS-CoV-2 SARS-COV-2 infection statin statins syndrome systemic inflammatory responses T-cells tested the SARS-CoV-2 viral immunology virus virus infectivity [DOI] 10.1093/oxfimm/iqaa001 PMC 바로가기 [Article Type] Short Communication
Cholesterol in Relation to COVID-19: Should We Care about It?Editorial Published on 2020-06-182022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] ACE2 activities acute respiratory syndrome addition angiotensin-converting enzyme 2 Anti-inflammatory Antithrombotic antiviral activity appear Atherosclerosis Blood cardiovascular complication cardiovascular disease caused cholesterol Clinical course complications of COVID-19 contributing to coronavirus Coronavirus infection COVID-19 critical appraisal current CVD Effects evidence of Hepatitis host cell hypertension immunomodulatory Infection influenza infection inhibitors intubation lipid-lowering therapy Lower Mortality Patient pharmacological interventions plasma membrane pleiotropic effect receptor reduce reducing relation reported risk S-protein SARS-CoV-2 SARS-CoV-2 main protease severity shown statin statins therapy viral clearance viral entry viral infection viral infectivity virus [DOI] 10.3390/jcm9061909 PMC 바로가기 [Article Type] Editorial
Reply to Siniorakis et al., “COVID-19 Interference with Renin-Angiotensin System in the Context of Heart Failure”Author Reply Published on 2020-05-292022-10-29 Journal: mBio [Category] Coronavirus, MERS, SARS, [키워드] “COVID-19 Angiotensin converting enzyme inhibitors Angiotensin receptor blockers Context COVID-19 heart Interference Neprilysin inhibitors Reply statins System [DOI] 10.1128/mBio.01243-20 PMC 바로가기 [Article Type] Author Reply
COVID-19, ACE2, and the cardiovascular consequencesArticle Published on 2020-05-012023-07-13 Journal: American journal of physiology. Heart and circulat [Category] SARS, [키워드] ACE2 Ang II COVID-19 renin-angiotensin system SARS-CoV-2 statins [DOI] 10.1152/ajpheart.00217.2020 PMC 바로가기
Statins as early therapy to mitigate COVID-19 (SARS-CoV-2)-associated ARDS and cytokine storm syndrome – time is of the essenceMedical Hypothesis Published on 2020-04-182022-10-29 Journal: Journal of Clinical and Translational Research [Category] COVID-19, [키워드] ACE 2 acute respiratory distress syndrome ARDS atorvastatin COVID-19 Cytokine storm Cytokine storm syndrome hyperinflammation microparticles mitigate SARS-CoV-2 statin statins therapy PMC 바로가기 [Article Type] Medical Hypothesis
Rosuvastatin Enhances VSV-G Lentiviral Transduction of NK Cells via Upregulation of the Low-Density Lipoprotein ReceptorArticle Published on 2020-03-292024-09-02 Journal: Molecular Therapy [Category] 대상포진, [키워드] GGPP LDLR lentiviral transduction Natural killer cells Rosuvastatin statins VSV-G [DOI] 10.1016/j.omtm.2020.03.017 PMC 바로가기 [Article Type] Article
Anti-tuberculous Effects of Statin Therapy: A Review of Literaturearticle Published on 2020-03-252024-09-02 Journal: Cureus [Category] 대상포진, [키워드] HMG-CoA reductase inhibitors Mycobacterium tuberculosis statins TB Tuberculosis [DOI] 10.7759/cureus.7404 PMC 바로가기 [Article Type] article
Opposite effects of statins on the risk of tuberculosis and herpes zoster in patients with diabetes: A population‐based cohort study당뇨병 환자에서 결핵 및 대상포진 위험에 대한 스타틴의 상반된 효과: 인구 기반 코호트 연구Original Article Published on 2020-01-282023-05-31 Journal: British Journal of Clinical Pharmacology [Category] 대상포진, 두창, 수두, 홍역, [키워드] Diabetes Mellitus herpes zoster lipid‐lowering agent statins Tuberculosis [DOI] 10.1111/bcp.14142 PMC 바로가기 [Article Type] Original Article