Effectiveness of disinfectants against the spread of tobamoviruses: Tomato brown rugose fruit virus and Cucumber green mottle mosaic virusResearch Published on 2021-01-062022-10-28 Journal: Virology Journal [Category] COVID-19, [키워드] absence activity addition Analysis ANOVA antibodies bioassay caused CGMMV Clorox collected contagious Cucumber disease disease control Disinfectants Effect effective Effectiveness Efficacy enzyme-linked immunosorbent equipment evaluate experiments identification independent Infection information inoculated observation outbreak plant plants preventative measure Result significant effect Spread Symptom Tobamovirus ToBRFV tomato Tomato and watermelon traits Transmission Viral diseases virus virus infectivity virus inoculum viruses was measured was performed was used [DOI] 10.1186/s12985-020-01479-8 PMC 바로가기 [Article Type] Research
The Genetic Dissection of Ace2 Expression Variation in the Heart of Murine Genetic Reference PopulationCardiovascular Medicine Published on 2020-11-202022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] ACE2 ACE2 receptor amplitude Analysis blood pressure BXD mice cardiac arrhythmias cardiac damage cardiovascular cardiovascular complication cardiovascular damage cell entry co-expressed co-expression correlated correlation COVID-19 COVID-19 patients cytokine diagnostic Diastolic blood pressure Dissection Electrocardiography eQTL eQTL mapping expression functional enrichment gene network gene regulaiton Genetic heart identify induce Inflammation Inflammatory involved Level locus mice morphology myocardial injury myocarditis network analysis outcome pathway Pathways Patient Population PPI Protein–protein interaction Quantitative range of variation RAS reference Regulation SARS-CoV SARS-CoV-2 virus signaling pathways significantly sinoatrial conduction strain Strains systemic inflammation TGFβ therapeutic purpose TNFα traits upstream vascular inflammation were used [DOI] 10.3389/fcvm.2020.582949 PMC 바로가기 [Article Type] Cardiovascular Medicine
Collider bias undermines our understanding of COVID-19 disease risk and severityArticle Published on 2020-11-122022-10-04 Journal: Nature Communications [Category] SARS, 치료법, [키워드] Affect analysed Analysing approach association behavioural Cohort collider bia collider bias COVID-19 COVID-19 disease dataset Epidemiology Evidence Genetic help highlight hospital identify induce Infection infection with SARS-CoV-2 Infectious diseases likelihood mechanism mitigate Numerous observational study outcomes participant Patient populations problems risk risk factor Risk factors sampling strategy SARS-CoV-2 pandemic selected severity Statistical methods Study design tested traits UK Biobank data variable while [DOI] 10.1038/s41467-020-19478-2 PMC 바로가기 [Article Type] Article
Causal Inference for Genetic Obesity, Cardiometabolic Profile and COVID-19 Susceptibility: A Mendelian Randomization Study유전적 비만, 심혈관 대사 프로필 및 COVID-19 감수성에 대한 인과 추론: 멘델식 무작위 배정 연구Genetics Published on 2020-11-112022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 association BMI body mass body mass index cardiometabolic cardiometabolic trait cardiometabolic traits category Causal cholesterol co-morbidity Cohort conducted confidence interval coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 Host Genetics Initiative COVID-19 infection Cox model Cox proportional hazard models European evaluate Genetic genetic risk genetic risk score genetic risk scores Genotype Glucose glycated hemoglobin hazard ratio HDL-cholesterol hemoglobin high-density High-density lipoprotein higher odd higher odds Hospitalization host genetics increased risk independent dataset independent datasets indicated individual Inference integration LDL LDL cholesterol lipid profile lipoprotein low-density Low-density lipoprotein mendelian randomization Modification morbidities MR analysis multivariable logistic regression obesity observational studies observational study Odds ratio parameter participant phenotype positive predictor present produced profile Quantitative reported respiratory Result risk Risk assessment risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity serum severe acute respiratory syndrome Coronavirus Standard deviation Support susceptibility Systolic blood pressure tested traits Treatment Triglyceride triglycerides UK biobank Waist circumference was performed [DOI] 10.3389/fgene.2020.586308 PMC 바로가기 [Article Type] Genetics
Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes인간 폐의 단일 세포 다중체 프로파일링은 SARS-CoV2 숙주 유전자의 세포 유형 특이적 및 연령 동적 제어를 보여줍니다Research Article Published on 2020-11-092022-09-10 Journal: eLife [Category] SARS, 변종, [키워드] age alveolar alveolar cell alveolar cells association cell types cells chromatin cis-regulatory elements COVID-19 dataset distal Donor donors element expressed facilitate focus functional Gene regulation Host host gene Human human lung human sequence variants immune implicated Interpretation locus lung lung cell Lung diseases Lungs mapped nuclei overlapped profile putative target genes receptor ACE2 Regulatory respiratory Respiratory failure reveal risk risk loci SARS-CoV-2 SARS-CoV-2 receptor SARS-CoV2 single cell RNA/ATAC-seq SLC6A20 Target genes the SARS-CoV-2 TMPRSS2 traits Transcriptome transcriptomes variant with COVID-19 [DOI] 10.7554/eLife.62522 PMC 바로가기 [Article Type] Research Article
A 2-Month Follow-Up Study of Psychological Distress among Italian People during the COVID-19 LockdownBrief Report Published on 2020-11-052022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] addition Administered age Anxiety association change changes changes in conditions coping strategies Coping strategy coronavirus disease COVID-19 Depression examined Factor Follow-up greater help identify increase in Italian Italian citizens Italy lockdown Measures mental health intervention multivariate National negative affect participant post-traumatic Psychological Psychological distress Psychological intervention Regression model Result risk Sociodemographic Spread Stress Symptoms t-test tested traits variables [DOI] 10.3390/ijerph17218180 PMC 바로가기 [Article Type] Brief Report
Predicting Perceived Stress Related to the Covid-19 Outbreak through Stable Psychological Traits and Machine Learning ModelsArticle Published on 2020-10-192022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Adults characterized Consequences Contagion contribute coping COVID-19 COVID-19 pandemic distress emotional Factors feature global public health greater implication individual Intervention Italian lockdown locus machine learning machine learning approach Mental mental health Model outbreak pandemic participant Perceived Perceived stress Personality physical positive Predictive Protective Psychological public health regressions SARS-CoV-2 sensitivity Sociodemographic stability STABLE Stress stress level subsequent traits variables women [DOI] 10.3390/jcm9103350 PMC 바로가기 [Article Type] Article
Emotional, Behavioral, and Psychological Impact of the COVID-19 PandemicPsychology Published on 2020-10-022022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] assist Behavior changed children component concerning Contamination country COVID-19 COVID-19 pandemic dissemination emotional Factors Gender Government group groups health authorities healthcare professionals human behavior Impact include increased risk individuals information internal and external measure media mental health mental health burden pandemic patients promote provided Psychiatric psychological changes Psychological outcome psychological support restricting measures SARS-CoV-2 social distancing social isolation Spread subjects traits virus World Health Organization [DOI] 10.3389/fpsyg.2020.566212 PMC 바로가기 [Article Type] Psychology
Differences in adherence to COVID-19 pandemic containment measures: psychopathy traits, empathy, and sexLetter to the Editors Published on 2020-09-222022-10-28 Journal: Trends in Psychiatry and Psychotherapy [Category] COVID-19, MERS, SARS, [키워드] COVID-19 pandemic difference Sex traits [DOI] 10.1590/2237-6089-2020-0055 PMC 바로가기 [Article Type] Letter to the Editors
The psychological impact of fertility treatment suspensions during the COVID-19 pandemicResearch Article Published on 2020-09-182022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] avoidance Canada coping strategies COVID-19 pandemic Depressive symptoms examined Factor Fertility greater help less media mental health participant Potential predictor Protective psychological Impact Psychological outcome Quality of life questionnaire recruited Result resulting seeking Support Suspension suspensions the United State traits Treatment variable women [DOI] 10.1371/journal.pone.0239253 PMC 바로가기 [Article Type] Research Article