Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes환기된 COVID-19 환자의 심각한 T 세포 과민반응은 장기간의 바이러스 지속성 및 나쁜 결과와 상관관계가 있습니다Article Published on 2021-05-212022-09-12 Journal: Nature Communications [Category] SARS, 바이오마커, 진단, 치료기술, 치료법, [키워드] basophils benefit blood sample caused Cell clinical recovery components coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient cytokine secretion dendritic cells downstream Effect extrinsic Factor female hospitalized COVID-19 patient hospitalized COVID-19 patients hyperinflammation identify IL-2 Immunosuppressive medication independent independent of male marker monocyte Monocytes neutrophil Neutrophils outcome overcome Patient patients plasma plasmacytoid dendritic cells Pneumonia polyclonal poor prognosis predict prolonged virus persistence reduced Respiratory distress syndrome respond SARS-CoV-2 SARS-CoV2 infection shown T cell T cell activation T cell response Ventilated ventilated patients viral infection viral persistence Whole blood [DOI] 10.1038/s41467-021-23334-2 PMC 바로가기 [Article Type] Article
Impact of early low-calorie low-protein versus standard-calorie standard-protein feeding on outcomes of ventilated adults with shock: design and conduct of a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3)Randomized Controlled Trial Published on 2021-05-112022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] acute phase Admission adult intensive & approved autophagy calory cellular clinical trials Critical Critical care defined dietetics discharge Ethics French functional Hospital-acquired infection hypothesised ICU ICUs Impact include Intensive intensive care Invasive mechanical ventilation management mechanically ventilated patient mechanism metabolic pathway Mortality multicentre nutrition & Open-label outcome outcomes parallel group parallel-group Patient peer-reviewed positive primary end-point primary endpoints Protein protein targets randomised receiving recent Restricting Result secondary Shock submitted Support target therapy Trial vasoactive amine Ventilated [DOI] 10.1136/bmjopen-2020-045041 PMC 바로가기 [Article Type] Randomized Controlled Trial
A numerical assessment of social distancing of preventing airborne transmission of COVID-19 during different breathing and coughing processesArticle Published on 2021-05-032022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] Asymptomatic carrier Bacteria Computational models Computational science Concentration conditions coughing COVID-19 Critical decrease disease droplet global pandemic infect infected patients investigated Navier–Stokes equation novel coronavirus disease Particle Respiratory system social distancing Spread Transmission Transport Ventilated Ventilation virus were used WHO [DOI] 10.1038/s41598-021-88645-2 PMC 바로가기 [Article Type] Article
Lupus Pneumonitis Therapy Masks Coronavirus (COVID-19)Case Report Published on 2021-04-082022-10-31 Journal: Case Reports in Rheumatology [Category] COVID-19, [키워드] Chest consolidation coronavirus COVID-19 CT scan Diagnosis female High-dose Hispanic Hospitalized hypoxic Inflammation interstitial Isolation Lupus Mask Myocardium Patient patients Pneumonitis pulmonary infiltrate renal resolved returned Shortness of breath Steroids Symptom syndrome tested the patient therapy treated upper lobe Ventilated [DOI] 10.1155/2021/6645780 PMC 바로가기 [Article Type] Case Report
The Experiences of Family Members of Ventilated COVID-19 Patients in the Intensive Care Unit: A Qualitative Study중환자실 코로나19 환기환자 가족의 경험: 정성적 연구Covid-19 Published on 2021-04-012022-09-01 Journal: The American Journal of Hospice & Palliative Care [Category] MERS, 진단, [키워드] adult COVID-19 patient adult COVID-19 patients analyzed Anxiety Care caused communication coronavirus coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 patient Critically ill Critically ill patient critically ill patients Diagnosis difficulty Effect end-of-life exacerbated experience exploratory expressed family family member family members Healthcare provider healthcare providers ICU include information intensive care intensive care unit intensive care units Limited member outcomes Palliative care pandemic Patient care preferences Qualitative question reaction reported seeking Stress Support the patient thematic analysis Ventilated virus Visitor while with COVID-19 [DOI] 10.1177/10499091211006914 PMC 바로가기 [Article Type] Covid-19
Increasing the efficiency of mechanical ventilators during pandemics through additive manufacturingSpecial Article Published on 2021-04-012022-10-27 Journal: Bosnian Journal of Basic Medical Sciences [Category] Coronavirus, Fulltext, MERS, SARS, [키워드] 24 hour 24 hours addition Additive manufacturing collected country COVID-19 COVID-19 pandemic cross-contamination determine Efficiency equipment expand help human lung increase in Increasing mechanical ventilator mechanical ventilators MOST multiplexer Pandemics parameter Patient Peak pressure Positive end-expiratory pressure required Research Respiratory failure reveal tested Usage Ventilated Ventilation ventilator Volume [DOI] 10.17305/bjbms.2020.5165 PMC 바로가기 [Article Type] Special Article
The impact of viremia on organ failure, biomarkers and mortality in a Swedish cohort of critically ill COVID-19 patients심각한 COVID-19 환자의 스웨덴 코호트에서 장기 부전, 바이오마커 및 사망률에 대한 바이러스혈증의 영향Observational Study Published on 2021-03-302022-09-10 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료기술, 치료법, [키워드] Acute inflammation admitted to ICU age association Biomarker blood stream Cohort Consent contribute coronavirus disease Coronavirus disease 2019 Corticosteroid corticosteroid treatment COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients death defined had more hypertension ICU admission ICU patient ICU Patients independent Inflammation Innate immunity Mortality Organ failure Patient PCR plasma renal replacement therapy replacement therapy RNA copies RNA copy SARS-CoV-2 SARS-CoV-2 RNA copies SARS-CoV-2 RNA copy SARS-CoV2 Spread suggested Swedish Trial registration Ventilated viral infection Viremia virus with COVID-19 [DOI] 10.1038/s41598-021-86500-y PMC 바로가기 [Article Type] Observational Study
High Incidence of Barotrauma in Patients With Severe Coronavirus Disease 2019Observational Study Published on 2021-03-152022-10-04 Journal: Journal of Intensive Care Medicine [Category] MERS, 임상, [키워드] acute lung injury Adult Airway Pressure artificial average mortality barotrauma cohort study coronavirus disease COVID-19 Critically ill patient demographics disease Evidence-based medicine greater group hospital Hospitalization ICU Illness severity Implications IMV incidence inclusion criteria increased mortality Inflammation Inflammatory response intensive care likelihood Los Angeles lung-protective ventilation median medication NIV no difference pathophysiology Patient patients with ARDS patients with COVID-19 Physiology Pneumonia proportion receiving Respiration Respiratory distress syndrome severe COVID-19 statistical significance sustained therapeutic anticoagulation Treatment Ventilated Ventilation Volume while with COVID-19 [DOI] 10.1177/0885066621989959 PMC 바로가기 [Article Type] Observational Study
Indoor Model Simulation for COVID-19 Transport and ExposureArticle Published on 2021-03-122022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] acute respiratory syndrome aerosol airways Combined complex coronavirus Correcting COVID-19 distribution dose expiratory droplet exposure female indoor aerosol modeling Infection infectious dose inhalation Inhaled inhaled dose male Model novel coronavirus disease Particles recipients reduced respiratory tract respiratory virus risk SARS-CoV-2 Simulation susceptible Transmission Transport Ventilated Ventilation virus [DOI] 10.3390/ijerph18062927 PMC 바로가기 [Article Type] Article
Ventilated Patients With COVID-19 Show Airflow ObstructionOriginal Research Published on 2021-03-112022-10-29 Journal: Journal of Intensive Care Medicine [Category] COVID-19, MERS, [키워드] acute respiratory distress age airflow airway Airway Pressure airway resistance All the patient analyzed Atypical calculated Characteristics city Compliance Contact coronavirus disease COVID-19 COVID-19 patient COVID-19 patients disease elevated expiratory female Final Follow-up information intensive care Invasive mechanical ventilation laboratory-confirmed mechanical ventilation obstruction Patient patients positive reduced Respiratory failure Respiratory mechanics Respiratory system setting show static compliance syndrome the patient university USA Ventilated ventilator was collected were excluded [DOI] 10.1177/08850666211000601 PMC 바로가기 [Article Type] Original Research