Emergent Change in a Mexican Midwifery Center Organization Amidst the COVID-19 CrisisSociology Published on 2021-02-092022-10-31 Journal: Frontiers in Sociology [Category] COVID-19, [키워드] Birth Care center change Chiapas conducted COVID-19 crisis deficiencies eight Evidence extreme Health Healthcare system hospital improvement International Mexico Mexico City Mexico DF Midwifery midwifery model of care organization out-of-hospital birth pandemic Pregnancy pregnant protocol recommendation Support women [DOI] 10.3389/fsoc.2021.611321 PMC 바로가기 [Article Type] Sociology
Modeling the effect of lockdown timing as a COVID-19 control measure in countries with differing social contactsArticle Published on 2021-02-082022-10-04 Journal: Scientific Reports [Category] MERS, 진단, [키워드] Analysis Applied mathematics Applying basic reproduction number Canada category China chose Complete Computational models Computational science country COVID-19 Critical distribution Effect eight expected hospital Hospitalization incidence lockdown Markov chain Measures modeling Niger outcomes pandemic parameter predict Prevent produced public health quantified reached reveal shown social contact social distancing was performed [DOI] 10.1038/s41598-021-82873-2 PMC 바로가기 [Article Type] Article
Composition analysis of falsified chloroquine phosphate samples seized during the COVID-19 pandemicCOVID-19 전염병 동안 압수된 위조 인산클로로퀸 샘플의 성분 분석Article Published on 2021-02-052022-08-31 Journal: Journal of pharmaceutical and biomedical analysis [Category] MERS, 치료제, [키워드] Analysis analyzed chloramphenicol Chloroquine Chloroquine phosphate Chromatography COVID-19 COVID-19 pandemic Democratic Republic eight global pandemic highlighting HPLC involved Laboratory liquid Liquid chromatography low dose Medicine metronidazole Niger Paracetamol performance phosphate proliferation public health Raman spectroscopy Substandard/falsified medicines Substitution trace amounts Vibrational spectroscopy. [DOI] 10.1016/j.jpba.2020.113761 PMC 바로가기 [Article Type] Article
The mechanism and active compounds of semen armeniacae amarum treating coronavirus disease 2019 based on network pharmacology and molecular dockingOriginal Article Published on 2021-02-042022-10-31 Journal: Food & Nutrition Research [Category] COVID-19, [키워드] 3CLpro ACE2 amygdalin AutoDock binding activity biological processes caspase-3 cellular component Chinese Clinical practice collected component Compound coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 Cytoscape database DAVID disease Disease network dissemination docking Effect EGFR eight endothelial enrichment analysis enzyme II epidermal GeneCards growth factor HRAS IL6 immunofluorescence indicated Inflammatory Injury Interaction KEGG Kyoto lung Lung inflammation MAPK MAPK1 MAPK3 mechanism mice modulating molecular docking molecular functions molecular mechanism network analysis network pharmacology nine objective OMIM Ontology outbreak pathway Pathways PPI Prevent protease Protein PubChem database public health receptor regulated Result retrieved SARS-CoV-2 Semen semen armeniacae amarum significantly increased SRC suggested target target prediction TCM TCMSP threat Transcription treated treating COVID-19 Treatment TTD Vascular VEGF VEGFA virus was used Western blot analysis [DOI] 10.29219/fnr.v65.5623 PMC 바로가기 [Article Type] Original Article
Synergistic and Antagonistic Drug Combinations against SARS-CoV-2SARS-CoV-2에 대한 시너지 및 길항 약물 조합Article Published on 2021-02-032022-09-11 Journal: Molecular therapy : the journal of the American So [Category] SARS, 신약개발, 치료제, [키워드] amodiaquine antagonistic antiviral efficacy Cell Combination combination therapy combinations coronavirus disease Coronavirus disease 2019 COVID-19 CPE CPE assay demonstrated disease drug Drug administration drug combination drug combinations Drug repurposing drug synergy drugs eight exhibiting food highlight Hydroxychloroquine in silico in silico approaches in silico design in vitro independent knowledge knowledge mining mechanism nitazoxanide nitazoxanide remdesivir combo. notable potential therapies potential therapy Preclinical Testing Remdesivir SARS-CoV-2 synergistic synergy tested therapeutic option treat umifenovir US Food and Drug Administration utility [DOI] 10.1016/j.ymthe.2020.12.016 PMC 바로가기 [Article Type] Article
The COVID-19 Elective for Pediatric Residents: Learning About Systems-Based Practice During a PandemicMedical Education Published on 2021-02-022022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome adjust Administered All participant Analysis Asynchronous learning Care clinical care Consequences coronavirus coronavirus disease COVID-19 COVID-19 pandemic COVID-19 testing Critically ill curriculum development and evaluation curriculum implementation develop ecosystem Effectiveness eight Elective emergency medicine - emergency critical care - disaster medicine hospital hospital response implementation IMPROVE incident learning systems include knowledge Laboratory learning local public health management Mental mental health pandemic participant pathophysiology pediatric pediatrics emergency Practice provide public health SARS-CoV-2 systems based practice [DOI] 10.7759/cureus.13085 PMC 바로가기 [Article Type] Medical Education
Lung and kidney perfusion deficits diagnosed by dual-energy computed tomography in patients with COVID-19-related systemic microangiopathyCOVID-19 관련 전신 미세혈관병증 환자에서 이중 에너지 컴퓨터 단층 촬영으로 진단된 폐 및 신장 관류 장애Article Published on 2021-02-012022-09-11 Journal: European Radiology [Category] 치료기술, [키워드] abnormality Admission albumin Anticoagulant Anticoagulants aspartate Aspartate aminotransferase AUROC C-reactive protein Characteristics Computed tomography Computed tomography angiography consolidation coronavirus coronavirus disease COVID-19 COVID-19 patients cutoff value D-dimer D-dimer level D-dimer levels diagnosed disease severity eight evaluated Evidence fibrinogen ground-glass opacity help heterogeneous Hospital stay Hypoxemia implication indication intensive care investigated Iodine kidney kidneys Laboratory laboratory findings lung management Mild-to-moderate occur overlapping Oxygenation Patient patients patients with COVID-19 Perfusion Physiology plasma predicted proportion pulmonary Pulmonary embolism Pulmonary thromboembolism sensitivity Serum ferritin severe disease SIGN significantly higher sodium sodium level specificity systemic microangiopathy Thromboembolism Thromboprophylaxis thrombosis thrombotic thrombotic event Thrombotic events tomography troponin troponin level troponin levels [DOI] 10.1007/s00330-020-07155-3 PMC 바로가기 [Article Type] Article
Decline in mild stroke presentations and intravenous thrombolysis during the COVID-19 pandemic: The Society of Vascular and Interventional Neurology Multicenter CollaborationObservational Study Published on 2021-02-012022-10-05 Journal: Clinical neurology and neurosurgery [Category] 임상, [키워드] administration Admission collaboration coronavirus COVID-19 COVID-19 pandemic Decline decrease diagnosed discharge discharge home discharged eight etiology evaluate greater hospital intravenous Ischemic Ischemic Stroke large vessel Large vessel occlusion Mild moderate multicenter observational study neurological NEUROLOGY NIHSS. outcome Patient proportion remained secondary severe disease severity Significant Society stratified stroke study period Subtypes the mean vessel Volume [DOI] 10.1016/j.clineuro.2020.106436 PMC 바로가기 [Article Type] Observational Study
A novel screening strategy of anti-SARS-CoV-2 drugs via blocking interaction between Spike RBD and ACE2Spike RBD와 ACE2 간의 상호 작용 차단을 통한 항 SARS-CoV-2 약물의 새로운 스크리닝 전략Article Published on 2021-02-012022-08-31 Journal: Environment international [Category] MERS, SARS, 치료제, [키워드] ACE2 activity angiotensin angiotensin converting enzyme anti-SARS-CoV-2 Anti-SARS-CoV-2 drugs screening strategy binding binding energy blockade Blockade mechanism Compound compounds Corona drug drug design Drug screening druggability eight enzyme exhibited hACE2 hesperidin highest human angiotensin converting enzyme 2 information Interaction investigated mechanism overcome pandemic RBD Receptor binding domain required S RBD SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 Spike RBD screening strategy spike Spread Structure Structure-activity relationship structures therapy Virus Disease [DOI] 10.1016/j.envint.2020.106361 PMC 바로가기 [Article Type] Article
A health worker knowledge, attitudes and practices survey of SARS-CoV-2 infection prevention and control in South AfricaArticle Published on 2021-02-012022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] addressed age Attitudes Care COVD-19 COVID-19 COVID-19 patient cross-sectional determine displaying eight element engage Ensuring Final Guidance Health health worker health workers healthcare hospital implementation indicated Infection prevention Interim involved knowledge knowledge score less limit Medical doctor Medical mask participant participated Patient perceptions PPE practices protocol provided question questionnaire reflected Result risk SARS-CoV-2 SARS-COV-2 infection significantly South Africa Study design study population transmission of SARS-CoV-2 utilised World Health Organization [DOI] 10.1186/s12879-021-05812-6 PMC 바로가기 [Article Type] Article