The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes
Research Article
[키워드] 2003
acute respiratory syndrome
ADP-ribose
amino-acid
Apoptosis
Author
bats
bind
binding
coding
compared
component
concerning
coronavirus
crystal structure
determine
determined
different
domain
Evidence
extreme
form
found
function
functional
G-quadruplex
gel electrophoresis
Genome
genomic RNA
help
homodimer
host cell
humans
immune response
in vitro
include
Infected
involved
lysine
macrodomain
mild infection
monomer
mRNA
Mutation
non-structural protein
nucleic acid
nucleotides
nucleus
occur
oligonucleotide
other coronaviruses
outbreak
pathogenicity
Possible
Protein
protein 3
reduction
Region
regulate
related virus
remained
Replication
residue
residues
responsible
RNA
SARS Coronavirus
SARS-CoV
selected
Seven
shown
Signal transduction
Structure
structures
target
three-dimensional structure
Transcription
viral infection
viral replication
virus
X-ray crystallography
[DOI] 10.1371/journal.ppat.1000428 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1000428 PMC 바로가기 [Article Type] Research Article