Safety of hydroxychloroquine and darunavir or lopinavir in COVID-19 infectionCOVID-19 감염에서 하이드록시클로로퀸과 다루나비르 또는 로피나비르의 안전성Observational Study Published on 2021-01-192022-09-11 Journal: Journal of Antimicrobial Chemotherapy [Category] 임상, 치료제, [키워드] age approach cardiovascular disease chronic cardiovascular clinical evaluations Clinical practice combination therapy Concentration condition COVID-19 COVID-19 infection COVID-19 pneumonia darunavir disease Drug interactions during treatment ECG abnormalities ECG abnormality eight electrocardiogram Electrocardiograms examined Hydroxychloroquine hypertension IMPROVE initial kidney Kidney failure Lopinavir Lopinavir/ritonavir males median median age Observational cohort study outcome Patient patients died patients hospitalized pharmacokinetics Pneumonia reversed Ritonavir Safety Seven significantly suggested the patient therapy treated Treatment with COVID-19 [DOI] 10.1093/jac/dkaa441 PMC 바로가기 [Article Type] Observational Study
An environmental study of tracheostomy on eight COVID-19 patientsOriginal Research Article Published on 2021-01-182022-10-29 Journal: Journal of Otolaryngology - Head & Neck Surgery [Category] COVID-19, [키워드] acute respiratory syndrome aerosol-generating procedure assistant Comorbidity contagious Contamination coronavirus coronavirus disease COVID-19 COVID-19 patient current defined eight Endotracheal intubation evaluate evaluated HCWs Health care worker intensive care intubation less pandemic Patient Personal protective equipment positive sample Positive test positive test result PPE recommendation Result risk Sample SARS-CoV-2 surgeon surgical tested throat swab tracheostomy Urine viral shedding [DOI] 10.1186/s40463-021-00494-1 PMC 바로가기 [Article Type] Original Research Article
Evaluation of the efficacy and safety of inhaled magnesium sulphate in combination with standard treatment in patients with moderate or severe COVID-19: A structured summary of a study protocol for a randomised controlled trial중등도 또는 중증 COVID-19 환자에 대한 표준 치료와 함께 흡입 황산마그네슘의 효능 및 안전성 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-01-182022-09-10 Journal: Trials [Category] 임상, [키워드] 1:1 acute severe asthma adjuvant therapy Administered Affect airway smooth muscle alveolar Anti-inflammatory anticipated Arm ARMS arterial blood arterial blood oxygen saturation arterial oxygen saturation arteriole Artery Asthma attack basic Blinding block Block randomisation blocks blood oxygen Blood oxygen saturation bradyarrhythmia calcium calcium antagonist cardiovascular disease cardiovascular diseases Chest computed tomography Chest CT chest CT scan clinical clinical impact clinical manifestation clinical manifestations Clinical studies clinical study clinical trials Combination Computed tomography Computer software Confirmed congestive heart failure Control Controlled trial cough COVID-19 criteria defined diagnosis of SARS-CoV-2 dissemination Dyspnoea Effect Effects Efficacy and safety eight element eligible patient Eligible patients excluded FIVE functional heart block hospital Hospital stay Hospitalized hospitalized patient hospitalized patients Hypoxemia hypoxia impairment IMPROVE improvement inclusion criteria induce Infection inhalation Inhaled Intervention intervention arm intravenous intravenously Length Lung injury lung involvement magnesium sulphate Mask moderate myocardial injury nasopharyngeal secretion National nebulized number objective Open-label outcome oxygen oxygen saturation Parallel Arm parenchyma participant Patient patients with moderate PCR performed polymerase chain polymerase chain reaction protocol pulmonary artery pulmonary involvement randomisation randomised randomised controlled trial randomization Randomly randomly divided RCT receive reduce Registered registration number registry respiratory respiratory airway respiratory airways Respiratory function respiratory tract respiratory tract symptoms Sample size SARS-COV-2 infection saturation severe COVID-19 Shortness of breath shown smooth muscle relaxant standard treatment status Study protocol supplementary material Symptom Tehran therapy Trial Trial registration Ventilation Version website with COVID-19 Yazd [DOI] 10.1186/s13063-021-05032-y PMC 바로가기 [Article Type] Letter
Abducens Palsy and Anosmia Associated with COVID-19: A Case ReportCase Report Published on 2021-01-182022-10-28 Journal: The British and Irish Orthoptic Journal [Category] COVID-19, [키워드] abducens palsy aberrant immune response Anosmia Care Case report clinician Complete COVID-19 COVID-19 disease COVID-19 infection cranial Cranial nerve palsy Diabetic diagnosed Diagnosis Diplopia Effect eight female had no healthy highlight horizontal diplopia Hypothesis individuals Inflammatory Injury latency measurement nerve damage neurological Neurological symptoms olfactory dysfunction Orthoptist palsy Patient positive public health raise rehabilitation report resolved Risk factors SARS-COV-2 infection Support Symptom the patient [DOI] 10.22599/bioj.167 PMC 바로가기 [Article Type] Case Report
Health conditions of potential risk for severe Covid-19 in institutionalized elderly peopleResearch Article Published on 2021-01-142022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] 95% CI adverse outcome age Analysis approach association BMI carried Chi-square Cognitive impairment condition contribute cross-sectional diabete diabetics disease eight elderly facility Factor Frequency Handbook Health health condition hypertension hypertensive identify individual Infection measure Natal Occurrence Odds ratio potential risk Protective Quantitative Region Rio Grande Risk factors Sociodemographic was used were used [DOI] 10.1371/journal.pone.0245432 PMC 바로가기 [Article Type] Research Article
Susceptibility Factors of Stomach for SARS-CoV-2 and Treatment Implication of Mucosal Protective Agent in COVID-19Medicine Published on 2021-01-142022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome agent analyzed average blockade coronavirus coronavirus disease COVID-19 diarrhea distribution eight Enterocyte epidemiological expressed expression Factor FIVE gel Genes GI symptom GI symptoms H pylori infection Helicobacter pylori Hospital stay hospitalized patient Infection initial intestinal intestinal metaplasia intestine investigated laboratory data material mucosa mucosal Patient Protective SARS-CoV-2 SARS-CoV-2 transmission Seven significant difference Single-cell RNA sequencing stomach susceptibility Symptom tablets the SARS-CoV-2 therapy TMPRSS2 two groups [DOI] 10.3389/fmed.2020.597967 PMC 바로가기 [Article Type] Medicine
Placental pathology of the third trimester pregnant women from COVID-19Case Report Published on 2021-01-142022-11-01 Journal: Diagnostic Pathology [Category] COVID-19, [키워드] 2019 novel coronavirus acute respiratory syndrome B cell cells Clinical characteristics Clinical management CoV COVID-19 cured demonstrated disease double staining eight evaluated Evidence Fluorescence gestation Hofbauer cells hybridization immunofluorescence immunohistochemistry Infection inflammatory cell information Macrophage monoclonal antibody outcome pathological change pathology Patient Placenta Placenta pathology placental Plasma cell Pregnancy pregnant women probe provided RNA SARS-CoV-2 spike protein SARS-CoV-2 virus serological evidence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) significantly increased Syncytial knots T cells The third trimester pregnancy tissue Transmission transmission of SARS-CoV-2 Vascular women [DOI] 10.1186/s13000-021-01067-6 PMC 바로가기 [Article Type] Case Report
Communication and Cooperation Between the Medical Academy, Medical Association, and Local Government: Health Counseling Program After Recovery From Coronavirus Disease 2019 (COVID-19) in DaeguPublic Health Published on 2021-01-132022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Academy association communication consultation cooperation Coronavirus disease 2019 counseling COVID-19 COVID-19 case COVID-19 pandemic COVID-19 patients discharged eight family Government Health healthcare Korean Local local government medical academia medical association Medicine overcome pandemic professionals Program psychological problem receiving recovered patient resource South Korea Spread Symptom [DOI] 10.3389/fpubh.2020.563757 PMC 바로가기 [Article Type] Public Health
Stability of SARS-CoV-2 on critical personal protective equipmentArticle Published on 2021-01-132022-10-29 Journal: Scientific Reports [Category] COVID-19, [키워드] applied characterized concerning confirmed cases COVID-19 transmission Critical Degradation different materials eight handling healthcare healthcare worker inoculated Masks N-95 Personal protective equipment Policy and public health in microbiology PPE provide representing Respirator SARS-CoV-2 SARS-CoV-2 stability SARS-CoV-2 virus spread of COVID-19 TCID Transmission Tyvek undetectable utility Virology virus [DOI] 10.1038/s41598-020-80098-3 PMC 바로가기 [Article Type] Article
Clinical and Demographic Characteristics Including Comorbidities and Their Outcomes Among Patients Hospitalized With COVID-19 in Four Tertiary Care Hospitals Across LahoreInternal Medicine Published on 2021-01-122022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Acute kidney injury acute respiratory syndrome baseline cardiovascular disease chest X-ray Chronic kidney disease classical clinical Clinical outcome collected Comorbidities Comorbidity conducted coronavirus coronavirus disease COVID-19 CVD death demographic demographic characteristics demographics descending Diabetes Mellitus Diabetic diagnosed died eight Female patients global pandemic Hospital stay Hospitalization hypertension hypertensive Including Infection initial intensive care interquartile range invasive Invasive mechanical ventilation male median median age Memorial objective outcome outcomes Patient patients patients hospitalized patients’ data positive pressure ventilation radiological finding renal replacement therapy Result Retrospective study RRT Sample size SARS-CoV-2 Tertiary tertiary care hospital total patients treated vital sign with COVID-19 Wuhan, China [DOI] 10.7759/cureus.12663 PMC 바로가기 [Article Type] Internal Medicine