Why, so far, have epidemics always eventually petered out? Quasispecies theory suggests a (testable!) answerArticle Published on 2018-05-012023-06-23 Journal: European Biophysics Journal [Category] 신종인플루엔자, [키워드] Epidemics Pandemics Propagation dynamics of infectious diseases Quasispecies [DOI] 10.1007/s00249-018-1306-2
Development of a Broadly Accessible Venezuelan Equine Encephalitis Virus Replicon Particle Vaccine PlatformVaccines and Antiviral Agents Published on 2018-03-142022-10-30 Journal: Journal of Virology [Category] Coronavirus, Fulltext, MERS, SARS, 조류인플루엔자, [키워드] addition Affect Aged antigen expression approach approaches biosafety BSL2 candidate vaccine condition coronavirus development disease effective Efficacy Epidemics Heterologous heterologous challenge human populations in vivo Laboratory majority mice microbial model systems Norovirus outbreak outcome Particle Pathogens platform provide public health recombinant proteins replicon reported reservoir robust Safe Taking utility vaccination Vaccine vaccine platform vaccine strain VEE replicon Venezuelan equine encephalitis virus virus-like particles viruses VRP while wild-type [DOI] 10.1128/JVI.00027-18 PMC 바로가기 [Article Type] Vaccines and Antiviral Agents
Molecular characterization of US-like and Asian non-S INDEL strains of porcine epidemic diarrhea virus (PEDV) that circulated in Japan during 2013–2016 and PEDVs collected from recurrent outbreaksResearch Article Published on 2018-03-142022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] affected Analysis analyzed ancestor antigenicity Asian caused changes in Characteristics circulating classical collected comparison develop Efficacy Endemic epidemic diarrhea Epidemics epitope full-length Genetic genetic heterogeneity glycosylation help introduced Japan Japanese Local M gene measure membrane Molecular epidemiology N gene North nucleocapsid outbreak Outbreaks parental PEDV phosphorylation sites Porcine epidemic diarrhea virus Proteins provide Region regions responsible Result resulting S gene sequence sequenced spike gene strain Strains subsequent substitutions suggested supplementary material the disease Vaccine vaccine strain virus [DOI] 10.1186/s12917-018-1409-0 PMC 바로가기 [Article Type] Research Article
Challenges of interpreting epidemiologic surveillance pertussis data with changing diagnostic and immunization practices: the case of the state of São Paulo, Brazil역학 감시 백일해 데이터 해석의 도전: 브라질 상파울루 주의 사례Research Article Published on 2018-03-132024-07-28 Journal: BMC Infectious Diseases [Category] 백일해, [키워드] Epidemics epidemiological surveillance pertussis vaccine Whooping cough [DOI] 10.1186/s12879-018-3004-1 PMC 바로가기 [Article Type] Research Article
Development of a one-step RT-PCR assay for detection of pancoronaviruses (α-, β-, γ-, and δ-coronaviruses) using newly designed degenerate primers for porcine and avian `fecal samplesArticle Published on 2018-02-272022-11-01 Journal: Journal of virological methods [Category] Coronavirus, MERS, [키워드] amplify Analysis Asia bat biological sample biological samples characterized conditions conserved Coronaviruses CoV CoVs Critical degenerate Degenerate primers demonstrated detect develop development domain ENCODE enteric diseases epidemic diarrhea Epidemics fecal gastroenteritis intestinal Laboratory measure Pancoronavirus RT-PCR pathogen PEDV Porcine deltacoronavirus positive primer Protein reported RNA RNA-dependent RNA polymerase RNA-dependent RNA polymerase (RdRP) gene RT-PCR RT-PCR assay RT-PCR assays Sensitivity and specificity sequenced sequenced samples sera serum samples tested universal primers virus [DOI] 10.1016/j.jviromet.2018.02.021 PMC 바로가기 [Article Type] Article
Converging Human and Malaria Vector Diagnostics with Data Management towards an Integrated Holistic One Health Approach인간과 말라리아 매개체 진단을 데이터 관리와 통합하여 통합적이고 전체적인 원헬스 접근법으로 수렴하기Review Published on 2018-02-032024-08-12 Journal: International Journal of Environmental Research and Public Health [Category] 말라리아, [키워드] diagnostics (Dx) Epidemics information and communication technologies (ICT) Insecticide resistance malaria one health vector-borne diseases [DOI] 10.3390/ijerph15020259 PMC 바로가기 [Article Type] Review
Antibodies to Influenza Virus Hemagglutinin in the 2016/2017 Epidemic Season in PolandArticle Published on 2018-01-012023-06-24 Journal: Advances in experimental medicine and biology [Category] 신종인플루엔자, [키워드] antibodies Epidemics hemagglutinin Influenza Protection factor Vaccine virus [DOI] 10.1007/5584_2018_232
Chimpanzee adenoviral vectors as vaccines for outbreak pathogensResearch Papers Published on 2017-12-302022-10-31 Journal: Human vaccines & immunotherapeutics [Category] Coronavirus, [키워드] adenoviral vector all age groups approach caused cellular Chimpanzee develop disease Drivers Ebola Epidemics Humoral immunity induce Infectious disease Lassa fever MERS MERS Co-V Nipah outbreak pathogen Pathogens platform pre-existing immunity Prostate cancer Safe Vaccine vaccine candidate Vaccines vector vectors Viral vector viral vectors West work [DOI] 10.1080/21645515.2017.1383575 PMC 바로가기 [Article Type] Research Papers
Vaccination history in elementary school children enrolled in the varicella epidemic investigations held in Jeju-si, Korea in the first half of 2017Article Published on 2017-11-132023-05-31 Journal: Epidemiology and Health [Category] Fulltext, 두창, 수두, 홍역, [키워드] Chickenpox vaccine Epidemics immunization vaccination varicella [DOI] 10.4178/epih.e2017053 PMC 바로가기
Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States미국 내 다양한 민족의 여러 인구에서 심혈관 질환 및 제2형 당뇨병에 대한 공유 유전 조절 네트워크Research Article Published on 2017-09-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activity African Americans alterations American Americans Amino acid amino acid metabolism amino acids biological processe biological processes branched-chain amino acids cardiovascular cardiovascular disease cardiovascular diseases cause causes CAV1 Cell culture co-expression Cohort commonality complex disease connection Critical CVD data-driven death diabetes disease Diseases Diversity driven by driver ENCODE Epidemics eQTLs expression expression quantitative trait loci Extracellular matrix finding FIVE functional Functional genomics gene knockout gene network gene networks Genetic genetic risk Genome-wide association study Glucose graphical models GWAS GWAS hit help Hispanic HMGCR human population human populations hybrid identify IGF1 immune response in vitro in vivo information Integrative analysis knockdown lipids loci mechanism metabolism molecular molecular network mouse Mouse models multidimensional multiple tissues network models neuronal offer overlapping Panel Pathogenesis pathogenic pathogenic processe pathway Pathways PCOLCE Population populations Quantitative Regulatory regulatory network Risk factors shared pathway shared pathways siRNA Strains Support T2D the United State therapeutic therapeutic target tissues type 2 diabete type 2 diabetes [DOI] 10.1371/journal.pgen.1007040 PMC 바로가기 [Article Type] Research Article