A cluster randomized controlled trial to increase the availability and acceptability of voluntary medical male circumcision in Zambia: The Spear and Shield Project잠비아에서 자발적인 의료 남성 할례의 가용성과 수용 가능성을 높이기 위한 클러스터 무작위 대조 시험: The Spear and Shield ProjectArticle Published on 2015-06-172022-09-06 Journal: The Lancet. HIV [Category] Communicable Disease, [키워드] 95% CI adjusted odds ratio adverse event adverse events assigned baseline Care center Cluster community health Community health centers conditions conducted Control Controlled trial counseling death expressed female finding funding Health Health care HIV HIV infection HIV prevention Intervention likelihood male men MOST Odds ratio participant Participants Participation Patient performed post-intervention Prevalence prevention programs Primary outcome randomization Randomized controlled trial Randomly reported Result Shield significant increase Spear statistician stratified study participation supply Support tested Trial registration [DOI] 10.1016/S2352-3018(15)00042-9 PMC 바로가기 [Article Type] Article
Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trialHIV-1에 감염된 건강한 성인에서 후보 결핵 백신 MVA85A의 안전성, 면역원성 및 효능: 무작위, 위약 대조, 2상 시험Articles Published on 2015-03-012022-09-06 Journal: The Lancet. Respiratory Medicine [Category] Communicable Disease, [키워드] 1:1 95% CI absence active tuberculosis adverse event Antigen antigen 85A antigen 85A-specific T-cell response antiretroviral Antiretroviral therapy assigned assist baseline baseline CD4 block blocks booster Cape CD4 count CD4 counts Cell clinical defined detect detectable Developing disease double-blind effective Efficacy eligible Eligible participants enrolled enrolment European Evidence evidence of expressing finding first vaccination foundation funding gold greater Group allocation had no healthy HIV-1 HIV-1 infection immunogenic immunogenicity include increased risk Infection injection intradermal injections investigators isoniazid isoniazid prophylaxis Laboratory latent tuberculosis latent tuberculosis infection M tuberculosis Measures Melinda Gate Melinda Gates modified vaccinia virus MVA85A Mycobacterium tuberculosis nine no evidence of Nurses occurred outcome participant partnership peaked per-protocol analysis per-protocol population Phase 2 phase 2 trial Placebo placebo group placebo-controlled positive Potential Prophylaxis protocol QuantiFERON QuantiFERON-TB Gold In-Tube randomisation randomised Randomly receive receiving Registered reported Safe Safety safety analysis second vaccination secondary Secondary outcomes sequence Serious Adverse Event Serious Adverse Events significant increase South Africa stratified subset T-cell Response the placebo group therapy town Treatment Trial Tuberculosis tuberculosis disease tuberculosis vaccine undetectable vaccination Vaccine vaccine efficacy vaccine-induced immune response Viral Viral load Wellcome Trust were assessed [DOI] 10.1016/S2213-2600(15)00037-5 PMC 바로가기 [Article Type] Articles
Porcine Epidemic Diarrhea Virus RNA Present in Commercial Spray-Dried Porcine Plasma Is Not Infectious to Naïve PigsResearch Article Published on 2014-08-122022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] addition Administered Alter antibody assigned Canada Cell culture component condition determine disease course epidemic diarrhea evaluate Evidence FIVE group indicate log naïve North America PEDV pig plasma positive post inoculation present raised Randomly remained RNA seroconvert seroconverted significantly Spread Transmission treatment groups virus [DOI] 10.1371/journal.pone.0104766 PMC 바로가기 [Article Type] Research Article
Intrahost Diversity of Feline Coronavirus: A Consensus between the Circulating Virulent/Avirulent Strains and the Internal Mutation Hypotheses?Research Article Published on 2013-03-272022-10-29 Journal: The Scientific World Journal [Category] Coronavirus, [키워드] Amino acid amino acid changes change circulating concerning coronavirus different Diversity evaluate found hypothese Hypothesis in vivo infectious internal Lineage M gene membrane molecular Mutation NO Pathogenesis positive Randomly sequence identity Sequencing SNP strain virulent virus [DOI] 10.1155/2013/572325 PMC 바로가기 [Article Type] Research Article
Prevalences of sexually transmitted infections in young adults and female sex workers in Peru: a national population-based survey페루의 젊은 성인과 여성 성노동자의 성병 유병률: 전국 인구 기반 조사Articles Published on 2012-10-012022-09-06 Journal: The Lancet. Infectious Diseases [Category] Communicable Disease, [키워드] accounted Adult age Blood C trachomatis Care Chlamydia trachomatis communicable communicable diseases enrolled female finding funding General population greater group help herpes simplex herpes simplex virus herpes simplex virus 2 HIV HIV infection HSV2 individual Infection Infectious disease initiative Intervention men men and women N gonorrhoeae National Neisseria gonorrhoeae nucleic acid nucleic acid amplification nucleic acid amplification tests Population positive Prevalence prevalences Randomly Registered risk selected serological test Serological tests Seven Sex sex workers sexually transmitted infections specimen stratified syphilis T vaginalis T-lymphotropic virus to define transmitted Trial Trichomonas vaginalis Urine virus with HIV women [DOI] 10.1016/S1473-3099(12)70144-5 PMC 바로가기 [Article Type] Articles
Pathogenesis and Tissue Distribution of Avian Infectious Bronchitis Virus Isolate IRFIBV32 (793/B Serotype) in Experimentally Infected Broiler ChickensResearch Article Published on 2012-04-012022-10-29 Journal: The Scientific World Journal [Category] Coronavirus, [키워드] age Antibody titer Broiler bronchitis chicken Clinical sign collected control group demonstrated Depression detected digestive distribution exhibited experimental group indicated Infected Infectious Bronchitis Virus inoculated intranasally isolate kidney lung mild respiratory number of infected oviduct Randomly RNA serotype tissue Trachea two group various tissue viral disease Viral RNA virus virus detection was reduced [DOI] 10.1100/2012/402537 PMC 바로가기 [Article Type] Research Article