Population-Specific ACE2 Single-Nucleotide Polymorphisms Have Limited Impact on SARS-CoV-2 Infectivity In Vitro인구 특이적 ACE2 단일 뉴클레오티드 다형성은 시험관 내 SARS-CoV-2 감염성에 제한적인 영향을 미칩니다Communication Published on 2021-01-062022-09-10 Journal: Viruses [Category] 유전자 메커니즘, [키워드] ACE2 ACE2 expression acute respiratory syndrome acute respiratory syndrome coronavirus Affect Analysis analyzed angiotensin angiotensin-converting enzyme 2 causative agent cell entry coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Efficiency eight enzyme except for host gene host genes human populations Impact in vitro indicated Infectivity Interaction Limited molecular dynamics Molecular dynamics simulation molecular dynamics simulations Mutation nonsense mutation performed polymorphism Population receptor Receptor binding reduced respiratory responsible SARS-2-S SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein selected severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity single-nucleotide Single-nucleotide polymorphisms SNP SNPs Spike protein susceptibility the SARS-CoV-2 validation study Viral viral cell viral cell entry [DOI] 10.3390/v13010067 PMC 바로가기 [Article Type] Communication
Placental Pathology in COVID-19: Case Series in a Community Hospital SettingObstetrics/Gynecology Published on 2021-01-062022-10-31 Journal: Cureus [Category] COVID-19, [키워드] activity Admission appearance Barnaba Blood Group center Coagulation Cohort control group coronavirus Coronavirus disease-19 COVID COVID-19 COVID-19 infection COVID-19 test death Department dysregulation eight Evidence examined feature fetal fibrin thrombi greater Grimace hypercoagulable incidence individual Infectious disease Inflammation Injury malperfusion maternal medicine microcalcifications microscopic features Monmouth MOST mother Nasopharyngeal swab Neonate objective obstetrics other variables outcome Patient perinatal pathology Placenta placental pathology positive positive COVID-19 pregnant women Prevalence Respiration Result Retrospective study Robert Sery setting surgical specimen tested virus with COVID-19 women wood [DOI] 10.7759/cureus.12522 PMC 바로가기 [Article Type] Obstetrics/Gynecology
Rehabilitation Exercise and psycholoGical support After covid-19 InfectioN’ (REGAIN): a structured summary of a study protocol for a randomised controlled trial재활 운동 및 심리적 지원 After covid-19 Infection'(REGAIN): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-01-062022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 age allocation concealment anticipated anxiety symptoms assessment automatically baseline Bengali best blind Blinding Care clinical clinically Cognitive function Complete computer-generated Controlled trial COVID-19 COVID-19 infection Critical care current death defined depressive determine dissemination Dyspnoea eight element email engage Engagement English exclusion criteria exercise Group allocation Health health economic evaluation health problems hospital hospital care hospital discharge include Informed consent life mental health mental health problem mental health problems NHS number objective Online outcome parallel group participant performed physical physical activity Physical health Post-traumatic stress disorder Practitioner Primary outcome profile protocol psychological support PTSD Quality of life questionnaire randomisation randomised randomised controlled trial rehabilitation Rehabilitation Exercise reported resource Sample size secondary Secondary outcomes sequence Standard status stratified Study protocol Support supported symptom severity Treatment Urdu usual care utility ventilatory ventilatory support Version web-based system website [DOI] 10.1186/s13063-020-04978-9 PMC 바로가기 [Article Type] Letter
Restrictive Lung Disease in Patients With Subclinical Coronavirus Infection: Are We Bracing Ourselves for Devastating Sequelae?Internal Medicine Published on 2021-01-052022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress affected angiotensin-converting enzyme 2 ARDS Asymptomatic case sery coronavirus disease COVID 19 COVID-19 COVID-19 diagnosis COVID-19 infection Diagnosis eight FIVE Ground-glass opacities Hospitalized ILD imperative Infection Interstitial lung disease manifestation Mild symptom pandemic Patient Post-COVID sequelae pulmonary fibrosis required Restrictive lung disease SARS-CoV-2 silent Subclinical symptomatic syndrome [DOI] 10.7759/cureus.12501 PMC 바로가기 [Article Type] Internal Medicine
Limits and Opportunities of SARS-CoV-2 Antigen Rapid Tests: An Experienced-Based PerspectiveCommunication Published on 2021-01-052022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Abbott addition analyzed Antigen benefit bronchoalveolar clinical setting correlation COVID-19 diagnostic eight evaluated gold standard Lateral flow test material opportunity PanBio PCR ranged Rapid Rapid antigen tests RapiGEN rising Roche SARS-CoV-2 SARS-COV-2 infection sensitivity specificity tested the SARS-CoV-2 [DOI] 10.3390/pathogens10010038 PMC 바로가기 [Article Type] Communication
Identifying and Responding to the Complex Needs of Domestic Violence Housing Practitioners at the Onset of the COVID-19 PandemicOriginal Article Published on 2021-01-052022-10-30 Journal: Journal of Family Violence [Category] COVID-19, [키워드] advocacy aligned Alliance Analysis analyzed COVID-19 COVID-19 mitigation COVID-19 pandemic domestic violence eight emotional expressed Factor Housing identifying Intimate partner violence maintain NASH Onset organization over pandemic participated platform Practitioner public health recommendation reduced Responding stability Support supported survivor the United State Violence [DOI] 10.1007/s10896-020-00231-8 PMC 바로가기 [Article Type] Original Article
Machine learning-based prediction of COVID-19 diagnosis based on symptomsArticle Published on 2021-01-042022-10-30 Journal: NPJ Digital Medicine [Category] COVID-19, [키워드] age approach assist can be used Contact COVID-19 COVID-19 case COVID-19 diagnosis COVID-19 test detect diagnosis of COVID-19 eight Epidemiology feature FIVE healthcare Healthcare systems high accuracy individual infected individual initial clinical symptoms machine machine-learning Ministry of Health mitigate patients Population screening predicted prediction reported resource resources Respiratory signs and symptoms risk of infection SARS-CoV-2 Sex subsequent Symptom tested [DOI] 10.1038/s41746-020-00372-6 PMC 바로가기 [Article Type] Article
Predictors and Prognostic Implications of Cardiac Arrhythmias in Patients Hospitalized for COVID-19Article Published on 2021-01-022022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Admission affected age analyses analyzed arrhythmia association Atrial fibrillation baseline characteristics Biomarkers cardiac Cardiac arrhythmia cardiac event cardiovascular cardiovascular conditions cardiovascular disease Clinical outcome Course COVID COVID-19 disease duration of hospitalization eight Hospitalization Hospitalized implication in-hospital mortality incidence increase in increased mortality Intensive mechanical ventilation medical record Multiple regression outcome pandemic parameter Patient patient subgroup patients predictor prognostic reported risk risk factor risk stratification [DOI] 10.3390/jcm10010133 PMC 바로가기 [Article Type] Article
Treatment of severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and coronavirus disease 2019 (COVID-19): a systematic review of in vitro , in vivo , and clinical trials중증급성호흡기증후군(SARS), 중동호흡기증후군(MERS), 코로나바이러스 감염증 2019(COVID-19)의 치료: 시험관 내, 생체 내 및 임상 시험에 대한 체계적인 검토Review Published on 2021-01-012022-09-10 Journal: Theranostics [Category] MERS, 비임상, 신약개발, 임상, 치료제, [키워드] acute respiratory syndrome article breath Clinical studies clinical study clinical trial Colchicine conducted controlled trials Convalescent plasma therapy coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 daclatasvir disease effective eight English Evidence help highlight identify in vitro In vitro studies in vivo information investigated MERS Meta-analysis Middle East Middle East respiratory syndrome Mortality Other outcome participant patients positive provide Randomized controlled trial rationale RCT RCTs Remdesivir required Research respiratory SARS Screening searched Severe acute respiratory syndrome sofosbuvir sofosbuvir/daclatasvir Spread syndrome systematic review therapeutic therapeutic agent therapeutic agents therapeutic effect therapy treating COVID-19 Treatment [DOI] 10.7150/thno.48342 PMC 바로가기 [Article Type] Review
Comparison of SARS-CoV-2 serological tests with different antigen targets다양한 항원 표적을 사용한 SARS-CoV-2 혈청 검사 비교Comparative Study Published on 2021-01-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 진단, 치료기술, 치료제, [키워드] added Antibody Response Antigen best CLIA Cohort Critically ill critically ill hospitalized patients cross-reaction cross-reactions detect diagnostic effort eight ELISA evaluated Evaluation exhibited expected FIVE heterogeneity hospitalized patient hospitalized patients IgA IgG IgG and IgM IgM IgM and IgG Kits majority positive positive RT-PCR reaction Reactions SARS-CoV-2 Sensitivity and specificity sera serological response serological test Serological tests serology Switzerland target tested the antibody response viruses [DOI] 10.1016/j.jcv.2020.104690 PMC 바로가기 [Article Type] Comparative Study