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[키워드] accompanied administration affected antibodies Antigen blood pressure bowel caused characterized contribute contributed coronavirus disease COVID-19 CRS cytokine cytokine production Cytokine release syndrome deficiency Degradation down-regulated expression Extracellular matrix HLA class II transgenic mice HLA-DR3 IFN-γ IL-17A immune Immunopathogenesis immunopathology indicated inflammatory pathway inhibitor inhibitors intestinal intestinal tissue JAK inhibitor janus kinase lethal maintain mice Mortality multiple organ multiple organ dysfucntion multiple organ dysfunction organ organ function pathogenic pathology pathway pro-apoptotic receptor Release RNA sequencing role SARS-CoV-2 selective severity signaling pathway significantly significantly increased specific treatment staphylococcal superantigens Support systemic level T cell T cell activation therapy Toxic shock syndrome transgenic mice Treatment TSS
[DOI] 10.3389/fimmu.2020.01311 PMC 바로가기 [Article Type] Immunology