ASO Author Reflections: Safety of Performing Esophageal Cancer Surgery During the First Wave of the COVID-19 Pandemic in Europe: A Multicenter StudyASO Author Reflections Published on 2021-03-242022-10-28 Journal: Annals of Surgical Oncology [Category] COVID-19, SARS, [키워드] ASO COVID-19 multicenter study Performing Safety surgery Wave [DOI] 10.1245/s10434-021-09891-2 PMC 바로가기 [Article Type] ASO Author Reflections
Mini-Review Discussing the Reliability and Efficiency of COVID-19 VaccinesReview Published on 2021-03-242022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] administration Adverse reactions affected age age and sex All adverse event alleviate approved article beta-coronavirus conducted coronavirus 2 COVID-19 database death develop died dose-dependent drug Effect Efficacy Efficacy and safety Evidence FIVE form Frequency individual Johnson & Johnson manuscript Mild Moderna Pfizer–BioNTech produced ranged recipient recipients reported respiratory Safe Safety SARS-CoV-2 searched severe adverse reactions Sex Side effects Sinopharm Sinovac the patient Vaccine Vaccines [DOI] 10.3390/diagnostics11040579 PMC 바로가기 [Article Type] Review
Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial영국에서 불리한 임상 경과의 위험이 높은 사람들에서 COVID-19가 의심되는 지역사회 치료를 위한 아지스로마이신(원칙): 무작위, 통제, 공개, 적응 플랫폼 시험Randomized Controlled Trial Published on 2021-03-202022-08-13 Journal: Lancet (London, England) [Category] Fulltext, SARS, 임상, 치료법, [키워드] adaptive Adaptive platform trial Admission analysed anti-inflammatory properties antibiotic Antibiotics antimicrobial resistance Antiviral assigned Azithromycin azothromycin Bayesian Bayesian logistic regression model Bayesian piecewise exponential Bayesian primary analysis BCI benefit both groups Clinical course clinically Community Comorbidity complications COVID-19 credibility interval death Department Effectiveness Eligible participants Endpoint enrolled Evidence evidence of finding Follow-up funding groups hazard ratio hospital Hospital admission hospitalisation hospitalised implication in both groups increased risk Innovation Intervention ISRCTN leads less logistic regression model median time multi-arm Older Open-label outcome pandemic participant platform primary analysis primary care principle Probability provided randomisation randomised Randomised trial Randomly recruited reducing Registered reported risk Safety safety analysis study group Time to recovery treat Treatment Trial use of antibiotics usual care usual care alone usual care group [DOI] 10.1016/S0140-6736(21)00461-X PMC 바로가기 [Article Type] Randomized Controlled Trial
COVID-19 Pandemic: What about the Safety of Anti-Coronavirus Nanoparticles?Review Published on 2021-03-192022-10-30 Journal: Nanomaterials [Category] COVID-19, [키워드] acute respiratory syndrome administration Antiviral assessments BNT162b2 cell entry Containment strategy coronavirus COVID-19 embryos Express facemasks highlight Human human–animal interfaces humans Impact in vitro in vivo information lung cell lines lung cells manuscript mRNA-1273 vaccines Nanoparticles Nanotoxicology Neurological symptoms new SARS-CoV-2 olfactory parameter performed Protein recent findings reported Safe Safety SARS-CoV-2 skeptical opinion supported the SARS-CoV-2 Toxicity vaccination variants zebrafish [DOI] 10.3390/nano11030796 PMC 바로가기 [Article Type] Review
Immunogenicity and safety profiles of a new MAV/06 strain varicella vaccine in healthy children: A multinational, multicenter, randomized, double-blinded, active-controlled phase III studyClinical Trial Published on 2021-03-192023-06-01 Journal: Vaccine [Category] 두창, 수두, 홍역, [키워드] children double blind immunogenicity MAV/06 strain multicenter Multinational phase 3 clinical trial Safety Varicella vaccine [DOI] 10.1016/j.vaccine.2021.02.013 [Article Type] Clinical Trial
A Commentary on Realities of Developing COVID-19 Vaccines Discussed through the Global Health Safety PerspectiveCommentary Published on 2021-03-182022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] addition addressed Affect affecting clinical trial COVID-19 COVID-19 vaccine develop Developing disease effective Efficiency effort explain global health global pandemic globe Health health safety perspective Health status Infection measure Perspective possible concerns potential risk realities REALITY reflect Safety SARS-CoV-2 Scientific community scientist Side effect Treatment vaccination Vaccine virus [DOI] 10.3390/vaccines9030274 PMC 바로가기 [Article Type] Commentary
Telitacicept Following Plasma Exchange in the Treatment of Subjects With Recurrent NMOSD: Study Protocol for a Single-Center, Single-Arm, Open-Label Studyarticle Published on 2021-03-182024-09-02 Journal: Frontiers in Neurology [Category] 대상포진, [키워드] clinical study Effectiveness Neuromyelitis optica spectrum disorders plasma exchange Safety Study protocol telitacicept [DOI] 10.3389/fneur.2021.596791 PMC 바로가기 [Article Type] article
Interleukin-6 blocking agents for treating COVID-19: a living systematic reviewCOVID-19 치료를 위한 인터루킨-6 차단제: 살아있는 체계적인 검토Meta-Analysis Published on 2021-03-182022-09-11 Journal: The Cochrane database of systematic reviews [Category] 임상, 진단, [키워드] 95% CI adverse event adverse events age all-cause mortality anti-IL6 approach articles available data average baseline benefit Bia blocking agent blocking agents Brazil can not Care certainty certainty of evidence China clinical Clinical improvement Cochrane COVID-19 Study Register collected data conducted coronavirus disease Coronavirus disease 2019 COVID-19 Critical Critical disease Data collection death defined disease disease severity Efficacy and safety eight evaluate evaluated Evidence excluded FIVE Follow-up France Health Organization heterogeneity hospital discharge identify IL-6 IL-6 blocking Immune system dysfunction immunosuppressive incidence Inclusion individual individual patient data meta-analyses Inflammation interleukin interleukin 6 interleukin 6 (IL-6 Intubated intubated patient intubated patients Italy male mechanical ventilation Meta-analysis methodology Mild moderate Mortality multicentre nine no increase not intubated organ support Other outcomes outcome outcomes oxygen participant Participants Patient patient data patients with COVID-19 peer-reviewed people with COVID-19 Placebo platform Platform trial progression proportion protocol randomised randomised controlled trial Randomised controlled trials ranged RCT RCTs reduce Registered registry reported risk of bia Safety sarilumab score searched Selection Serious Adverse Event Serious Adverse Events Seven severe coronavirus disease severity siltuximab standard care Standard of care subgroups of patient systematic review Tocilizumab Tolerance Treatment Trial trial participant trial participants trials unlikely USA WHO World Health Organization [DOI] 10.1002/14651858.CD013881 PMC 바로가기 [Article Type] Meta-Analysis
Clinical Evaluation of an Immunochromatographic-Based IgM/IgG Antibody Assay (GenBody™ COVI040) for Detection of Antibody Seroconversion in Patients with SARS-CoV-2 InfectionArticle Published on 2021-03-172022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] 95% confidence interval Accuracy acute respiratory syndrome anti-SARS-CoV-2 IgM antibody approval clinical collected coronavirus coronavirus disease COVID-19 COVID-19 patients detection diagnostic diagnostic accuracy study diagnostic test drug evaluate food IgG IgM IgM/IgG immunochromatography Immunoglobulin Immunoglobulin G immunoglobulin M in vitro Korean MONITOR negative control sample Patient polymerase chain PSO Safety SARS-CoV-2 SARS-CoV-2 antibody sensitivity Sensitivity and specificity Seroconversion South specificity symptom onset tested were used [DOI] 10.3390/diagnostics11030537 PMC 바로가기 [Article Type] Article
Effects and Safety of Convalescent Plasma Administration in a Group of Polish Pediatric Patients with COVID-19: A Case SeriesArticle Published on 2021-03-172022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] abnormality adverse effect age analyzed C-reactive protein children Chronic diseases clinical Clinical course Comorbidities convalescent plasma Course COVID-19 D-dimer defined described Effect group Hospitalization Infection knowledge Laboratory parameters lymphopenia median medical history Mild Nasopharyngeal swab Patient Pediatric patient plasma RT-PCR Safety SARS-CoV-2 SARS-COV-2 infection Sery Supportive treatment symptom onset the mean the SARS-CoV-2 therapy transfusion treated Treatment treatment for COVID-19 viral clearance virus elimination [DOI] 10.3390/life11030247 PMC 바로가기 [Article Type] Article