Challenges of following patients with inherited metabolic diseases during the COVID-19 outbreak. A cross-sectional online survey studyArticle Published on 2020-11-122023-07-12 Journal: Journal of pediatric endocrinology & metabolism : JPEM [Category] SARS, [키워드] COVID-19 Inherited metabolic disorders online survey SARS-CoV2 [DOI] 10.1515/jpem-2020-0441
Identification of saquinavir as a potent inhibitor of dimeric SARS-CoV2 main protease through MM/GBSAArticle Published on 2020-11-122023-07-12 Journal: Journal of molecular modeling [Category] SARS, [키워드] docking MD simulations protease SARS-CoV2 [DOI] 10.1007/s00894-020-04600-4 PMC 바로가기
Analysis of COVID-19 Cases’ Spatial Dependence in US Counties Reveals Health InequalitiesPublic Health Published on 2020-11-122022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] 2019 coronavirus disease American analyzed autocorrelation available data black caused Characteristics confirmed case coronavirus correlated correlation COVID-19 COVID-19 case death deaths dependence distribution Health health rankings healthcare Hispanic incidence of COVID-19 individual inequality Infectious disease intensive care mitigate neighborhood Novel coronavirus pandemic positive resource SARS-CoV2 severity significantly socio-demographic Spatial autocorrelation Spread the disease The United States variable Variation virus WHO World Health Organization [DOI] 10.3389/fpubh.2020.579190 PMC 바로가기 [Article Type] Public Health
Incidence of COVID-19 in patients with rheumatic disease: is prior health education more important than shielding advice during the pandemic?Brief Report Published on 2020-11-112022-10-31 Journal: Clinical Rheumatology [Category] COVID-19, MERS, [키워드] 95%CI age changes in Clinical practice co-morbidity Cohort condition COVID-19 COVID-19 in patient COVID-19 pandemic disorder effective ENhance examined giant cell arteritis Guidance Health Health Education hospital identify incidence incidence of COVID-19 incidence rate include infection risk information Laboratory likelihood medication National pandemic Patient patients Point population level PROTECT public health reduce reducing rheumatic disease rheumatoid arthritis rheumatological rheumatology risk risk factor Risk factors risk stratification SARS-CoV-2 SARS-CoV2 scored shielding Transmission transmission of SARS-CoV-2 Treatment vulnerable patient while [DOI] 10.1007/s10067-020-05494-6 PMC 바로가기 [Article Type] Brief Report
Sex differences in COVID-19: the role of androgens in disease severity and progressionCOVID-19의 성별 차이: 질병 중증도 및 진행에서 안드로겐의 역할Review Published on 2020-11-112022-09-10 Journal: Endocrine [Category] MERS, SARS, 변종, [키워드] affected androgen Androgen receptor Androgen receptors androgens CAG repeats children clinical trial condition COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 progression COVID-19 treatment Critical Dexamethasone disease disease severity drug Evidence evidence of explain facilitate fatality help Hospitalization Host Hydroxychloroquine implicated Infection men morbidity Mortality nitric oxide outcome outcomes pandemic pathophysiology Pathways Patient percentage prepubertal progression promoter Prostate cancer protease receptor Result SARS-CoV2 SARS-CoV2 infection sensitivity Sensitivity test sensitivity tests Serine serine 2 sex hormone Sex hormones Spike proteins suggested Testosterone therapy TMPRSS2 Transcription transmembrane protease serine 2 Treatment variants Viral viral infectivity virus spike protein women [DOI] 10.1007/s12020-020-02536-6 PMC 바로가기 [Article Type] Review
Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes인간 폐의 단일 세포 다중체 프로파일링은 SARS-CoV2 숙주 유전자의 세포 유형 특이적 및 연령 동적 제어를 보여줍니다Research Article Published on 2020-11-092022-09-10 Journal: eLife [Category] SARS, 변종, [키워드] age alveolar alveolar cell alveolar cells association cell types cells chromatin cis-regulatory elements COVID-19 dataset distal Donor donors element expressed facilitate focus functional Gene regulation Host host gene Human human lung human sequence variants immune implicated Interpretation locus lung lung cell Lung diseases Lungs mapped nuclei overlapped profile putative target genes receptor ACE2 Regulatory respiratory Respiratory failure reveal risk risk loci SARS-CoV-2 SARS-CoV-2 receptor SARS-CoV2 single cell RNA/ATAC-seq SLC6A20 Target genes the SARS-CoV-2 TMPRSS2 traits Transcriptome transcriptomes variant with COVID-19 [DOI] 10.7554/eLife.62522 PMC 바로가기 [Article Type] Research Article
COVID-19 infection: Disease detection and mobile technologyGlobal Health Published on 2020-11-092022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] 2019-nCoV acute respiratory syndrome affected article center China Chinese clinical trial community transmission Control coronavirus coronavirus disease country COVID-19 disease disease spread disease transmission Epidemiology etiology IMPROVE include literature review mitigate Mobile Mobile technology Nanotechnology Nature novel beta-coronavirus outbreak pandemic performed Pneumonia potential treatments Precaution prevention promote PROTECT provide reduce responsible Result SARS-CoV-2 SARS-CoV2 Self-isolation social distancing Spread took place Treatment Vaccine wearing face mask World Health Organization Wuhan [DOI] 10.7717/peerj.10345 PMC 바로가기 [Article Type] Global Health
[Prediction of end of lockdown post-peak of cases in first wave of the COVID-19 pandemic in Chile]Article Published on 2020-11-092023-07-12 Journal: Medwave [Category] SARS, [키워드] 2019 novel coronavirus 2019-nCoV coronavirus COVID-19 Forecasting quarantine SARS-CoV2 [DOI] 10.5867/medwave.2020.10.8057
A Risk Prediction Model for Evaluating the Disease Progression of COVID-19 PneumoniaMedicine Published on 2020-11-052022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome age Algorithm Analysis caused China Cohort cohorts Comorbidities coronavirus coronavirus disease COVID 19 COVID-19 CREA diabetes Disease progression enrolled Epidemic evaluate Evaluating Factor Fever help hospital hypertension identify Infection Laboratory LDH Logistic Logistic regression men Meta-analysis Model neutrophil count Patient Pneumonia prediction progression risk risk factor Risk prediction model SARS-CoV2 Severe COVID-19 pneumonia shown significantly sSARS—CoV-2 table the disease the median validation cohort validation cohorts was performed with COVID-19 women Wuhan [DOI] 10.3389/fmed.2020.556886 PMC 바로가기 [Article Type] Medicine
Quarantine at home may not enough!-from the epidemiological data in Shaanxi Province of ChinaResearch Note Published on 2020-11-042022-10-27 Journal: BMC Research Notes [Category] COVID-19, [키워드] 2019 coronavirus disease 2019 novel coronavirus 2019-nCoV age Asymptomatic average Characteristics children China Cluster COVID-19 Critical epidemiological epidemiological data Epidemiological features Family cluster females male Mild moderate objective parent Patient patients Pneumonia Result SARS-CoV2 [DOI] 10.1186/s13104-020-05342-5 PMC 바로가기 [Article Type] Research Note