Antigen-Independent Restriction of Pneumococcal Density by Mucosal Adjuvant Cholera Toxin Subunit B항원 비의존성 폐렴구균 밀도의 점막 보조제 콜레라 독소 서브유닛 B에 의한 제한journal-article Published on 2016-11-152024-08-01 Journal: Nanoscale [Category] 폐렴구균 감염증, [키워드] bacterial colonization bacterial density cholera toxin subunit B Inflammasome macrophages mucosal adjuvant Streptococcus pneumoniae T cells [DOI] 10.1093/infdis/jiw160 [Article Type] journal-article
Sex-Differential Non-Vaccine-Specific Immunological Effects of Diphtheria-Tetanus-Pertussis and Measles Vaccination디프테리아-파상풍-백일해 및 홍역 백신의 성별 차이에 따른 비백신 특정 면역학적 효과Article Published on 2016-11-012024-08-18 Journal: Clinical infectious diseases : an official publication of the Infectious [Category] 백일해, 파상풍, [키워드] Cytokines heterologous effects Innate immunity T cells Transcriptome
The convergence of senescence and nutrient sensing during lymphocyte ageingarticle Published on 2016-10-282024-09-02 Journal: Clinical and experimental immunology [Category] 대상포진, [키워드] aging cell differentiation inhibitory/activating receptors Natural killer cells T cells [DOI] 10.1111/cei.12876 PMC 바로가기 [Article Type] article
MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic diseaseResearch Published on 2016-09-072023-06-13 Journal: Journal of Neuroinflammation [Category] MERS, [키워드] Demyelination miR-155 Neuroinflammation T cells virus [DOI] 10.1186/s12974-016-0699-z PMC 바로가기 [Article Type] Research
Evaluation of protective immune response against fowl typhoid in chickens vaccinated with the attenuated strain Salmonella Gallinarum ΔcobSΔcbiAarticle Published on 2016-08-312024-09-01 Journal: Research in Veterinary Science [Category] 살모넬라증, [키워드] acquired immunity BMDM flow cytometry live vaccine T cells [Article Type] article
Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity비복제 Toxoplasma gondii Uracil Auxotrophs에 의한 Rhoptry 및 Dense Granule Effector 단백질의 분비는 항종양 면역의 발달을 제어합니다Research Article Published on 2016-07-222022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] abrogated activate activated acute infection Auxotroph auxotrophic mutants axis CD4 CD8 Cell Nucleus Cell signaling cellular signaling pathway cellular signaling pathways conjunction Control deleted Deletion dendritic cells Dense development effective effective therapy effector effector molecule effector molecules effector protein effector proteins function Granule GTPase GTPases Host host cell host cell nucleus host cell response Host immune response host immune responses host innate immunity host response host responses identify IFN-γ immune responses Immune suppression Immunity independent Infection interferon Invasion latent infection mammalian cell mechanism membrane mice mutant not affect nucleus ovarian cancer parasite pathway Pathways Protein required responses rhoptry Safe secreted secretion shown Signaling solid tumor solid tumors survival T cell T cells target therapeutic These data Toxoplasma gondii transcriptional Trigger Tumor tumor microenvironment tumors type I uracil vaccination vaccine strain virulence [DOI] 10.1371/journal.pgen.1006189 PMC 바로가기 [Article Type] Research Article
A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to NeuroinflammationT 세포 수용체 신호 분자 Vav1의 천연 변이체는 이펙터 T 세포 기능과 신경 염증에 대한 감수성을 모두 감소시킵니다Research Article Published on 2016-07-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Activation Affect alteration Antigen antigen receptor Autoimmune candidate gene CD4 T cell CD4 T cells changes in chromosome 9 Control cytokine cytokine production Cytokines Diseases effector effector T cell effector T cells FOXP3 function functions Genetic genetic study GM-CSF guanine highlight IFN-γ IL-17 immune system immunization Inflammatory cytokine Inflammatory cytokines intrinsic leads locus mechanism mice MOG molecule natural Neuroinflammation Non-synonymous normal enzymatic activity nucleotide peptide phenotype physiological polymorphism Polymorphisms proportion Quantitative receptor reduce reduced Regulatory T cell regulatory T cells Signaling susceptibility T cell T cell receptor T cells Th1/Th17 These data transducing Treg variant Vav1 [DOI] 10.1371/journal.pgen.1006185 PMC 바로가기 [Article Type] Research Article
Collagen-induced arthritis and imiquimod-induced psoriasis develop independently of interleukin-33Research Article Published on 2016-06-182023-08-29 Journal: Arthritis Research & Therapy [Category] E형 간염, [키워드] Arthritis IL-33 psoriasis T cells [DOI] 10.1186/s13075-016-1042-x PMC 바로가기 [Article Type] Research Article
Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease InhibitorResearch Article Published on 2016-03-302022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] 3CLpro Animal coronaviruses Antiviral compound antiviral drug antiviral drugs Antiviral treatment cause caused cell tropism contributed coronavirus Coronavirus infection Coronavirus infections Cross-species transmission death disease Diseases effective Efficacy and safety evaluated experimental evidence facilitate fatal disease fatality feature Feline infectious peritonitis Fever full recovery Health Host Human humans immune response Immune-mediated infect inflammatory disease inhibitor Laboratory less lymphopenia mammalian measure Mild Mutation other coronavirus pathogen Pathogenesis progression protease Protease inhibitor recombination rate reduction in Replication reported required respiratory resulting returned reversal risk Significant T cells therapeutic therapeutic efficacy therapeutic strategy tissue Treatment viable treatment viral titer virulence virulent virus virus replication [DOI] 10.1371/journal.ppat.1005531 PMC 바로가기 [Article Type] Research Article
Insights into the naturally acquired immune response to Plasmodium vivax malariaarticle Published on 2016-02-282024-09-01 Journal: Parasitology [Category] 말라리아, [키워드] antibodies naturally acquired immunity Plasmodium vivax T cells [Article Type] article