Incomplete Plasmodium falciparum growth inhibition following piperaquine treatment translates into increased parasite viability in the in vitro parasite reduction ratio assayarticle Published on 2024-04-302024-09-01 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] 4-aminoquinoline drug resistance growth inhibition assay parasite viability Piperaquine PRR assay [Article Type] article
4-Aminoquinolines modulate RNA structure and function: Pharmacophore implications of a conformationally restricted polyamineArticle Published on 2023-02-122023-07-11 Journal: Biochemical and Biophysical Research Communication [Category] COVID19(2023년), [키워드] 4-aminoquinoline Drug discovery RNA binding SARS-CoV-2 stem-loop II motif (s2m) T-box riboswitch. [DOI] 10.1016/j.bbrc.2022.12.080
Current status of 4-aminoquinoline resistance markers 18 years after cessation of chloroquine use for the treatment of uncomplicated falciparum malaria in the littoral coastline region of Cameroonarticle Published on 2022-12-312024-09-01 Journal: Pathogens and Global Health [Category] 말라리아, [키워드] 4-aminoquinoline alleles buea drug resistance Pfcrt Pfmdr1 Plasmodium falciparum [Article Type] article
Liquid Chromatographic Methods for COVID-19 Drugs, Hydroxychloroquine and ChloroquineCOVID-19 약물, 하이드록시클로로퀸 및 클로로퀸에 대한 액체 크로마토그래피 방법Review Published on 2021-08-182022-09-11 Journal: Journal of chromatographic science [Category] SARS, 치료기술, 치료제, [키워드] 4-aminoquinoline Arthritis Autoimmune diseases biologic biological fluid biological fluids Chloroquine clinical trial clinical trials Complete country Course COVID-19 Determination doctor drug epidemiological studies facilitate HCQ Hydroxychloroquine information liquid lupus erythematosus malaria metabolite Patient pharmaceutical preparations Pharmacodynamics pharmacokinetics provide reported Research rheumatoid arthritis Safe supervision systemic lupus erythematosus Treatment treatment regimen [DOI] 10.1093/chromsci/bmaa110 PMC 바로가기 [Article Type] Review
AQ-13 – an investigational antimalarial drugArticle Published on 2019-03-312024-09-09 Journal: Expert Opin Investig Drugs [Category] 말라리아, [키워드] 4-aminoquinoline AQ-13 Chloroquine clinical development malaria Plasmodium falciparum Plasmodium vivax resistance PMC 바로가기
Quinoline-Based Hybrid Compounds with Antimalarial Activity퀴놀린 기반 하이브리드 화합물의 항말라리아 활성이미지Review Published on 2017-12-192024-08-12 Journal: Molecules [Category] 말라리아, [키워드] 4-aminoquinoline 8-aminoquinoline hybrid compound Infectious disease malaria [DOI] 10.3390/molecules22122268 PMC 바로가기 [Article Type] Review
In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti- P. falciparum and Anti- P. vivax Blood-Stage Antimalarial퀴놀리진으로 변형된 4-아미노퀴놀린의 인 비보 및 인 비트로 활성 및 ADME-독성 프로필: 강력한 P. falciparum 및 P. vivax 혈액 단계 항말라리아제Article Published on 2017-12-012024-08-12 Journal: Molecules [Category] 말라리아, [키워드] 4-aminoquinoline drug resistance malaria P. falciparum P. vivax [DOI] 10.3390/molecules22122102 PMC 바로가기 [Article Type] Article
Antimalarial activity of novel 4-aminoquinolines active against drug resistant strainsArticle Published on 2017-02-282024-09-09 Journal: Bioorg Chem [Category] 말라리아, [키워드] 4-aminoquinoline antimalarial Heam binding Plasmodium falciparum PMC 바로가기
Synthesis and Evaluation of Chirally Defined Side Chain Variants of 7-Chloro-4-Aminoquinoline To Overcome Drug Resistance in Malaria ChemotherapyArticle Published on 2017-02-232024-08-27 Journal: Med Instrum [Category] 말라리아, [키워드] 4-aminoquinoline antimalarial agents chloroquine resistant quinolines
Synthesis, β-hematin inhibition studies and antimalarial evaluation of dehydroxy isotebuquine derivatives against Plasmodium bergheiArticle Published on 2015-08-012024-08-29 Journal: Bioorganic & Medicinal Chemistry [Category] 말라리아, [키워드] 4-aminoquinoline Antimalarial activity Haemozoin formation Isotebuquine malaria β-Hematin