Paucity of cutaneous manifestations of COVID-19 among inpatients at a referral hospital in IndiaResearch article Published on 2022-09-012022-10-05 Journal: JAAD International [Category] 진단, [키워드] 48 hour Admission causes Coagulopathy Comorbidity conducted COVID toes COVID-19 cross-sectional cross-sectional analysis Cutaneous cutaneous manifestation described diagnosed digital ischemia drug DVT hospital ICU patient ICUs India Inpatient intensive care unit moderate morbilliform rash mottling objective Patient patients with moderate peer review Prognosis Result RT-PCR severe COVID-19 severe disease skin systemic urticaria with COVID-19 [DOI] 10.1016/j.jdin.2022.01.001 [Article Type] Research article
Predictive Factors of Extubation Failure in COVID-19 Mechanically Ventilated PatientsObservational Study Published on 2022-09-012022-10-04 Journal: Journal of Intensive Care Medicine [Category] 임상, [키워드] 48 hour 95% CI Admission age Analysis APACHE II score association average Characteristics COVID-19 COVID-19 patient dialysis evaluate evaluated extubation Factor failure ICU increased the risk independent predictor intensive care invasive investigated male mechanical ventilation need for dialysis non-COVID-19 patient Non-COVID-19 patients on mechanical ventilation outcome PaO2/FiO2 ratio parameter Patient Poisson regression model predicted Predictive Predictive Factors predictor Primary outcome Probability progressed retrospective risk Sex single-center statistical analysis Symptom Symptoms the mean the patient was done was performed weaning with COVID-19 [DOI] 10.1177/08850666221093946 PMC 바로가기 [Article Type] Observational Study
Severe refractory warm autoimmune haemolytic anaemia after the SARS-CoV-2 Pfizer-BioNTech vaccine (BNT162b2 mRNA) managed with emergency splenectomy and complement inhibition with eculizumabArticle Published on 2022-08-312022-11-15 Journal: BMJ case reports [Category] SARS, 진단, [키워드] 48 hour Autoimmune Bilirubin Blood BNT162b2 mRNA Chest complement Complement pathway Corticosteroid described disease eculizumab fatigue first dose haematology (incl blood transfusion) Haemoglobin highlight inhibitor initiated investigation jaundice lactate dehydrogenase life-threatening liver male over Pfizer-BioNTech SARS-CoV-2 standard treatment the patient the SARS-CoV-2 transplantation Urine Vaccine warm was performed [DOI] 10.1136/bcr-2022-250774 PMC 바로가기
Impact of Severe Acute Respiratory Syndrome Coronavirus 2-Induced COVID-19 on Fixed Operating Room Times in Urologic OperationsResearch article Published on 2022-08-012022-10-05 Journal: Mayo Clinic Proceedings: Innovations, Quality & Outcomes [Category] 치료기술, [키워드] 48 hour acute respiratory syndrome AGSartificial genitourinary sphincter anesthesia-release to cut time ARCTanesthesia-release to cut time artificial genitourinary sphincter caused CIconfidence interval close to wheels-out time collected confidence interval coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19coronavirus disease 2019 CTWOclose to wheels-out time Efficiency evaluate examined fixed group Impact impacted in-room to anesthesia-release time in-room to cut time include interquartile range IQRinterquartile range IRATin-room to anesthesia-release time IRCTin-room to cut time objective Operating room operation ORoperating room over Patient polymerase chain respiratory Result room SARS-CoV-2severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 time variable was used Wilcoxon rank sum [DOI] 10.1016/j.mayocpiqo.2022.06.002 [Article Type] Research article
mRNA-1273 vaccination protects against SARS-CoV-2-elicited lung inflammation in nonhuman primatesmRNA-1273 백신 접종은 비인간 영장류에서 SARS-CoV-2 유발 폐 염증으로부터 보호합니다Article Published on 2022-07-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), SARS, 변종, [키워드] 48 hour 48 hours Antibody Response Antibody responses Antibody titer Bronchoalveolar lavage fluid CCL3 cellular Cellular immune response chemokines collected correlated COVID-19 CXCL10 dissemination dose-dependent manner expression Genes Human IFIT1 immune immunology independent induction Inflammation Inflammatory ISG15 less limit Lower respiratory tract lung Lung inflammation mRNA mRNA-1273 MX1 observation Pathogenesis profile PROTECT replicated respiratory tract restrict viral replication rhesus macaque rhesus macaques SARS-CoV-2 SARS-CoV-2 antibody response SARS-CoV-2 antibody responses SARS-CoV-2 spike SARS-CoV-2 strain serum Support suppressed These data transcriptomic USA-WA1/2020 vaccination Vaccine-induced immunity variant of SARS-CoV-2 viral infection viral replication Viral RNA [DOI] 10.1172/jci.insight.160039 PMC 바로가기 [Article Type] Article
Post-COVID-19 Conditions Among Children 90 Days After SARS-CoV-2 InfectionSARS-CoV-2 감염 90일 후 어린이의 코로나19 이후 상태Article Published on 2022-07-012022-09-11 Journal: JAMA Network Open [Category] COVID19(2023년), SARS, 치료기술, [키워드] 48 hour 48 hours 95% CI acute illness addition adjusted odds ratio age children cohort study condition conditions conducted controls country Day defined enrolled Factor fatigue Follow-up Frequency Health Hospitalization Hospitalized index IQR median age nucleic acid nucleic acid testing Older outcome positive positive test result problem proportion prospective cohort study recruitment reported risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity Symptom test result tested the median weakness [DOI] 10.1001/jamanetworkopen.2022.23253 PMC 바로가기 [Article Type] Article
Safety evaluation of the single-dose Ad26.COV2.S vaccine among healthcare workers in the Sisonke study in South Africa: A phase 3b implementation trial남아프리카의 Sisonke 연구에서 의료 종사자를 대상으로 한 단회 용량 Ad26.COV2.S 백신의 안전성 평가: 3b상 시행 시험Clinical Trial Published on 2022-06-212022-09-12 Journal: PLoS Medicine [Category] MERS, 임상, 진단, [키워드] 48 hour Ad26.COV2.S vaccine adverse event AEs African age body ache breakthrough infections categories clinical clinical trials collected COVID-19 COVID-19 infection death demonstrated Effectiveness eligible evaluated expected Fever Final first vaccination Frequency HCW HCWs headache healthcare healthcare worker hospitalisations Immune system disorder implementation Implementation study IMPROVE incidence rate increasing age Infection injection site pain janssen men morbidity MOST National nervous system disorder occurred Open-label Pan participant Participants Phase 3 trials reactogenicity reactogenicity event Registered registry reported SAE SAEs safety evaluation safety profile serious AE single-arm design South South Africa Support Symptoms syndrome System thrombosis Trial triggered vaccination Vaccine [DOI] 10.1371/journal.pmed.1004024 PMC 바로가기 [Article Type] Clinical Trial
Control of CDH1/E-Cadherin Gene Expression and Release of a Soluble Form of E-Cadherin in SARS-CoV-2 Infected Caco-2 Intestinal Cells: Physiopathological Consequences for the Intestinal Forms of COVID-19SARS-CoV-2에 감염된 Caco-2 장 세포에서 CDH1/E-Cadherin 유전자 발현 및 가용성 형태의 E-Cadherin 방출 제어: COVID-19의 장 형태에 대한 생리병리학적 결과Article Published on 2022-05-042022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 치료기술, 치료제, [키워드] 24 hour 24 hours 48 hour 48 hours ACE2 ACE2 mRNA Affect AT1 Caco-2 Caco-2 cell Caco-2 cells cadherin CDH1 Cell cell line cells Co-receptor connexin consequence contributing to Control COVID-19 Culture culture supernatant diarrhoea diarrhoea) digestive tract Disruption dissemination down-regulated dysregulation E-cadherin ENCODE epithelial exposure to expresse expression form Gastrointestinal symptom gastrointestinal symptoms gastrointestinal tract HCoV HCoV-OC43 HLA class I human ACE2 illnesses in viral induce infected with SARS-CoV-2 Infection intestinal Intestinal barrier intestinal cells intestinal tissue intranasal involved JAMA junctions leads membrane mRNA mRNA expression OC43 occludin pandemic Patient Physiopathological Post-infection Protein receptor receptor ACE2 Release remained reported respiratory respiratory tract SARS-CoV-2 SARS-COV-2 infection significant increase significantly lower Symptom the disease these symptoms TMPRSS2 Transcription transgenic mice Trigger Viral viral entry virus [DOI] 10.3389/fcimb.2022.798767 PMC 바로가기 [Article Type] Article
Bacterial co-infection at hospital admission in patients with COVID-19Observational Study Published on 2022-05-012022-10-05 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 임상, [키워드] 48 hour Analysis Antibiotics Antigen Bacterial bacterial co-infection Bacterial infection Barcelona Blood clinic clinician Co-infection cohort study COVID-19 cultures described ferritin ferritin level Haemophilus influenzae Hospital admission hospitalized patient incidence inclusion criteria independent risk factor microbiologically microorganism MOST oxygen saturation Patient patients patients hospitalized patients with COVID-19 PCT pneumococcal procalcitonin risk factor SARS-CoV-2 significantly more sputum culture Staphylococcus aureus Streptococcus pneumoniae Test was performed with COVID-19 [DOI] 10.1016/j.ijid.2022.03.003 PMC 바로가기 [Article Type] Observational Study
The role of procalcitonin results in antibiotic decision-making in coronavirus disease 2019 (COVID-19)코로나바이러스 질병 2019(COVID-19)에서 프로칼시토닌의 역할이 항생제 의사 결정Observational Study Published on 2022-05-012022-09-11 Journal: Infection Control and Hospital Epidemiology [Category] 바이오마커, 임상, [키워드] 24 hours 48 hour 48 hours 95% CI abnormal added antibiotic Antibiotic therapy Antibiotics Bacterial Characteristics clinical criteria community-acquired pneumonia confounders coronavirus disease COVID-19 COVID-19 patient COVID-19 patients died Duration elevated evaluate evaluated Evidence evidence of groups hospital Hospitalization Hospitalized initial interquartile range IQR Johns Hopkin Johns Hopkins median no evidence of observational study Patient patients PCT Pneumonia procalcitonin receipt receiving retrospective ROC ROC Curve ROC curves therapy transferred were excluded [DOI] 10.1017/ice.2021.175 PMC 바로가기 [Article Type] Observational Study