6 hours – Communicable Diseases Research

Conservative treatment with mouthwashes followed by tongue photo biomodulation therapy in Covid-19: a case report

Article

Published on 2022-10-062022-11-15
Journal: Journal of Medical Case Reports
[Category] 치료제,

Management and Outcomes of COVID – 19 Associated Cerebral Venous Sinus Thrombosis

Observational Study

Published on 2022-04-012022-10-05
Journal: Journal of stroke and cerebrovascular diseases : t
[Category] 임상,

[키워드] 6 hours Activation appear C-reactive protein cerebral Cerebral venous thrombosis Characteristics clinical study Coagulation COVID COVID-19 COVID-19 infection D-dimer Decompressive hemicraniectomy. described Diagnosis disease elevated Endothelium in both groups increasingly Infection Inflammatory marker involved Laboratory majority management mechanism median time Mortality offer outcome outcomes pandemic Pathways Patient patients positive presenting symptoms prospective observational study reported respiratory scale second wave Seizure serum single center Sinus south India survived Symptom systemic tested the mean thrombosis Transverse sinus treated triggering venous
[DOI] 10.1016/j.jstrokecerebrovasdis.2022.106306 PMC 바로가기 [Article Type] Observational Study

Emergency air evacuation of patients with acute respiratory failure due to SARS-CoV-2 from Mayotte to Reunion Island

마요트에서 레위니옹 섬으로 SARS-CoV-2로 인한 급성 호흡 부전 환자의 긴급 대피

Observational Study

Published on 2021-12-032022-09-11
Journal: Medicine
[Category] SARS, 변종, 임상,

[키워드] 501Y.V2 6 hours Acute respiratory failure acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age air evacuation ARF Case series case sery consecutive patient coronavirus curare death Emergency episode episode of evaluated extracorporeal membrane oxygenation Factor feasible hospital Hospitalized Hypoxemia ICU ICU admission intensive care intensive care unit Invasive mechanical ventilation island lack Mayotte median age observational study occurred Patient patients patients with SARS-CoV-2 Pneumonia positive receiving remained Respiratory failure retrospective SARS-CoV-2 SARS-CoV-2 pneumonia screened sedated severe acute respiratory syndrome Coronavirus severe hypoxemia Support tested the median the SARS-CoV-2 Transport Travel travel time Treatment university variant
[DOI] 10.1097/MD.0000000000027881 PMC 바로가기 [Article Type] Observational Study

Evolution of COVID-19 Pregnancies Treated With Nitazoxanide in a Third-Level Hospital

Obstetrics/Gynecology

Published on 2021-05-132022-10-31
Journal: Cureus
[Category] COVID-19,

[키워드] 6 hours analyzed coronavirus coronavirus disease COVID-19 cross-sectional deaths ectopic FIVE in vitro activity intensive care nine nitazoxanide Patient positive pregnancies Pregnancy pregnant pregnant women puerperium receive Result safety profile Seven treated vaginal delivery women
[DOI] 10.7759/cureus.15002 PMC 바로가기 [Article Type] Obstetrics/Gynecology

Standard Care Versus Awake Prone Position in Adult Nonintubated Patients With Acute Hypoxemic Respiratory Failure Secondary to COVID-19 Infection—A Multicenter Feasibility Randomized Controlled Trial

COVID-19 감염에 따른 급성 저산소성 호흡부전이 있는 성인 삽관되지 않은 성인 환자의 깨어 있는 자세와 깨어 있는 자세 비교 - 다기관 타당성 무작위 대조 시험

Randomized Controlled Trial

Published on 2021-05-052022-08-13
Journal: Journal of Intensive Care Medicine
[Category] MERS, 임상,

[키워드] 6 hour 6 hours acute hypoxic respiratory failure acute respiratory distress acute respiratory distress syndrome adverse events Awake prone positioning clinical trial conditions conducted Controlled COVID-19 COVID-19 pneumonia exceeded failure feasibility Feasibility study feasible group help hypoxia hypoxic respiratory failure knowledge maintain no significant difference non-intubated patient non-intubated patients observational studies observational study outcome oxygen pandemic parallel group Patient Pneumonia position Primary outcome prone prone group Prone position prone positioning proportion protocol Randomized rationale recruited requiring supplemental oxygen respiratory respiratory distress Respiratory failure Result Safe saturation secondary outcome Secondary outcomes secondary to significant difference Standard standard care supine supine group supplemental oxygen syndrome Trial with COVID-19
[DOI] 10.1177/08850666211014480 PMC 바로가기 [Article Type] Randomized Controlled Trial

Early versus deferred anti-SARS-CoV-2 convalescent plasma in patients admitted for COVID-19: A randomized phase II clinical trial

COVID-19로 입원한 환자의 조기 및 지연된 항-SARS-CoV-2 회복기 혈장: 무작위 2상 임상 시험

Clinical Trial

Published on 2021-03-032022-08-13
Journal: PLoS Medicine
[Category] Biochemistry, 임상, 진단,

[키워드] 6 hour 6 hours 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition administration age aggravation anti-SARS-CoV-2 antibody ARMS benefit carried clearance rate clinical benefit Clinical deterioration clinical trial clinically Composite conducted convalescent patient Convalescent patients convalescent plasma coronavirus Corticosteroids COVID-19 COVID-19 patients COVID-19 progression COVID-19 symptom CP group criteria death detect Deterioration Donor early stage early stages Efficacy Efficacy and safety Elvira Enrollment evaluate Evidence evidence of except for Final Follow-up groups high risk hospital Hospitalization hospitalized patient hospitalized patients IMPROVE In-hospital death in-hospital mortality in-hospital mortality rate Intervention lack male matter mechanical ventilation Mortality mortality rate Neutralizing antibodies neutralizing antibody not differ observation observations Odds ratio on mechanical ventilation Open-label outcome pandemic participant Patient patients hospitalized patients with COVID-19 performed plasma Plasma transfusion presenting Primary outcome progression proportion Randomized randomized clinical trial randomized patient randomized trial Real-time PCR recruited required researcher respiratory Respiratory failure risk factor Risk factors SARS-CoV-2 secondary outcome Serious Adverse Event Serious Adverse Events severe acute respiratory syndrome Coronavirus single-center small sample size standard treatment Statistical power symptomatic symptomatic COVID-19 Symptoms the patient therapeutic effect therapy Treatment Trial Two patient two patients Viral viral clearance rate virus with COVID-19
[DOI] 10.1371/journal.pmed.1003415 PMC 바로가기 [Article Type] Clinical Trial

Modelling of hypothetical SARS-CoV-2 point-of-care tests on admission to hospital from A&E;: rapid cost-effectiveness analysis

A&E에서 병원 입원 시 가상 SARS-CoV-2 현장 진료 테스트 모델링: 신속한 비용 효율성 분석

Article

Published on 2021-03-012022-09-11
Journal: Health technology assessment (Winchester, England)
[Category] SARS, 치료기술, 치료제,

[키워드] 6 hours Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus Admission allocation analysis Analysis appear assessment benefit calibration Care cause caused clinical effectiveness coronavirus coronavirus disease Coronavirus disease 2019 cost-effectiveness COST–BENEFIT ANALYSIS COVID-19 death diagnostic Diagnostic accuracy diagnostic tests disease emergency department example Future hospital Hospital wards hospitals hypothetical identify in some infections information intensive care Isolation journal Laboratory testing less library limitations mitigate Mortality NHS NIHR Occupancy outcomes parameter Patient performed Perspective point-of-care point-of-care systems point-of-care test point-of-care tests produced profile recorded reduced reduction reduction in SARS-CoV-2 SARS-CoV-2 test severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Severe acute respiratory syndrome coronavirus 2. Spread synthesis technology Technology assessment Test test result Viral detection virus website were recorded writing
[DOI] 10.3310/hta25210 PMC 바로가기 [Article Type] Article

Homeopathy for Covid-19 in Primary Care: A structured summary of a study protocol for a randomized controlled trial

일차 진료에서 Covid-19에 대한 동종 요법: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-02-012022-08-31
Journal: Trials
[Category] MERS, 임상, 치료제,

[키워드] 1:1 6 hour 6 hours acute respiratory syndrome Adverse adverse events alcohol alternative hypothesis appearance blinded Blinding block randomization bottle Brazil changed changes chest pain clinical trial cough COVID-19 defined dissemination dose double-blind Effectiveness elapsed element emergency services Fever followed by headache Home isolation homeopathic medicine homeopathic medicines Homeopathy hospitalizations identity Influenza Influenza-like symptoms Informed consent investigators measure medication Medicine Medicines Mild mild case mild cases muscle aches network null hypothesis number objective Older outcome Pain participant performed Placebo placebo-controlled positive RT-PCR primary care primary endpoint Primary Health Care protocol randomisation randomised Randomized Randomized controlled trial Randomized Controlled Trial protocol recorded Recovery time recruitment Registered required respiratory Sample size SARS-CoV-2 secondary Severe acute respiratory syndrome shakes sore throat statistician status study medication Study protocol submitted supplementary material Symptom Telemedicine Time to recovery tiredness treatment group Trial two group two groups Unified Health System university website without symptoms
[DOI] 10.1186/s13063-021-05071-5 PMC 바로가기 [Article Type] Letter

Virucidal effect of povidone iodine on COVID-19 in the nasopharynx: A structured summary of a study protocol for an open-label randomized clinical trial

비인두에서 COVID-19에 대한 포비돈 요오드의 바이러스 살균 효과: 공개 라벨 무작위 임상 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-01-042022-09-10
Journal: Trials
[Category] 임상,

[키워드] 6 hour 6 hours acute renal failure adverse effect adverse effects adverse event adverse events anticipated Arm-1 ARMS assigned baseline being randomized Blinding both groups chronic renal failure clinical trial college comparator Concentration conducted confirmed case COVID-19 COVID-19 case COVID-19 virus creatinine criteria Data analysis diagnosed diet disease dissemination distilled water DMC Efficacy element eligibility assessment estimated glomerular filtration rate evaluate exclusion filtration rate Final glomerular filtration rate groups Identifier in both groups include Inclusion inclusion criteria independent Informed consent Intervention intervention arm intervention arms intervention group invasive involved Iodine KDIGO lactating masking Microsoft Excel Modification nasal Nasal Irrigation Nasal spray nasopharynx Noninvasive ventilation number objective Occurrence Open-label Other outcome parallel-group participant Patient performed Placebo positive Povidone Iodine pregnant women Primary outcome proportion protocol random number generation randomization Randomized randomized clinical trial RCT receive recruited Registered renal renal disease renal failure required routine care Sample size screened sealed secondary outcome sensitivity Seven single-center Stage statistician status Study protocol supplementary material Symptom Thyroid thyroid disease Trial trial protocol Trial registration Version virucidal virus website
[DOI] 10.1186/s13063-020-04963-2 PMC 바로가기 [Article Type] Letter

A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial

중환자실에 입원한 COVID-19 환자의 정맥 주사 멜라토닌의 효능과 안전성을 조사하기 위한 2상, 단일 센터, 이중 맹검, 무작위 위약 대조 시험(MelCOVID 연구): 연구 프로토콜의 구조화된 요약 무작위 대조 시험을 위해

Letter

Published on 2020-08-052022-08-13
Journal: Trials
[Category] MERS, 임상,

[키워드] 6 hours Acute hypoxemic respiratory failure addition Admission Adult patients adverse effect adverse event adverse events age allocation anticipated Autoimmune disease Biochemical parameters blinded Blinding blood gas blood gas analysis body weight C-reactive protein Caregivers carried chronic Chronic kidney disease clinical condition clinical development commercialization comparator compatible symptom compatible symptoms Complete completion computer conducted Confirmed Consent Control control arm control group COVID-19 COVID-19-associated thromboembolic phenomena Critically ill D-dimer daily dose Date determined by disease dissemination double-blind Efficacy and safety element enzyme EU Clinical Trial evaluate evaluate the effect exclusion criteria expected experimental arm experimental group failing organ failing organs family member ferritin Frequency gas analysis GFR greater hematologic Hemodialysis hypoxemic Hypoxemic respiratory failure ICU ICU admission impairment Inclusion inclusion criteria increase in inflammatory state Informed institutional protocols intensive care intensive care unit interleukin interleukin-6 intravenous Kidney disease legal guardian less liver enzymes maximum mechanical ventilation medical illness melatonin Mortality multi-organ failure normal range number objective Organ failure outcome parameters participant Patient patient condition patients with COVID-19 per day performed phase physician Placebo placebo-controlled randomized trial plasma Plasma levels positive RT-PCR Pregnancy pregnancy test Prevent procalcitonin Program protocol provided randomization randomization sequence Randomized Randomized controlled trial randomized placebo-controlled trial receive recruited recruitment reduced reduction Respiratory failure Sample size SARS-COV-2 infection SAS version 9.4 SAS version 9.4 statistical software secondary Secondary objectives Sequential Organ Failure Assessment severity single center single-center SOFA Spain Stage Standard-of-care statistical status study drug study group study groups study period Study protocol systemic inflammatory response Terminal surgical thromboembolic Treatment Trial Trial registration two-arm parallel Ventilator-free days website with COVID-19 worsening written Informed Consent
[DOI] 10.1186/s13063-020-04632-4 PMC 바로가기 [Article Type] Letter