Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cellsOmicron이 아닌 조상 SARS-CoV-2는 일차 소아 비강 상피 세포에서 덜 효율적으로 복제합니다Article Published on 2022-08-012022-09-11 Journal: PLoS Biology [Category] Coronavirus, SARS, 변종, [키워드] acute respiratory syndrome Adults Air-liquid interface antiviral response Biology biology of SARS-CoV-2 changes in children coronavirus 2 coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 Delta delta variant epithelial cells Evidence Infection infections less Mild symptom nasal epithelial cell nasal epithelium NEC NECs omicron pediatric replicate replicated Replication respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly lower Support susceptible These data vaccination Viral RNA virus VOCs widespread [DOI] 10.1371/journal.pbio.3001728 PMC 바로가기 [Article Type] Article
Sigmoid colon perforation in a SARS-CoV-2 positive neonate: a uniqueness report and a brief reviewReview Published on 2022-06-032023-07-09 Journal: BMC Pediatrics [Category] COVID19(2023년), [키워드] Colonic perforation COVID-19 intestinal perforation NEC Neonate Newborn SARS-CoV-2 Sigmoid perforation. [DOI] 10.1186/s12887-022-03392-1 PMC 바로가기 [Article Type] Review
Infection prevention for extremely low birth weight infants in the NICUReview Published on 2022-06-012023-07-09 Journal: Seminars in fetal & neonatal medicine [Category] COVID19(2023년), [키워드] Antibiotics Extremely low birth weight infant fungemia Infection prevention Late onset sepsis NEC Neonate NICU Probiotics SARS-CoV-2 Very low birth weight infant. [DOI] 10.1016/j.siny.2022.101345 PMC 바로가기 [Article Type] Review
The short-term effects of RBC transfusions on intestinal injury in preterm infants Research Published on 2022-02-042022-10-05 Journal: Pediatric Research [Category] 바이오마커, [키워드] age Biomarker Blood Cell change correlated Effect Effects fatty Impact increase in Infant Injury intestinal intestinal cell intestinal injury Loss Lower magnitude maintain median NEC organs oxidative stress oxygen saturation oxygen supply Oxygenation Pathogenesis Protein RBC red blood cell representing Result Splanchnic transfusion Treatment urinary Variability were assessed [DOI] 10.1038/s41390-022-01961-9 [Article Type] Research
Human Nasal Epithelial Cells Sustain Persistent SARS-CoV-2 Infection In Vitro , despite Eliciting a Prolonged Antiviral ResponseResearch Article Published on 2022-01-182022-10-29 Journal: mBio [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] absence Alpha Analysis Antiviral apical surface Apoptosis Atf3 basal cells Cell cell death cell type characterized contributing to COVID-19 COVID-19 patient DDIT3 disease Eliciting epithelia epithelial expression Factor gene signature host response Human Immune cell Immunocompromised patient infected NEC Infection interferon response investigated involved management nasal Nasal Epithelial cells NEC Necrosis Patient persistence persistent Postinfection Prolonged provide replicate Replication response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus Signaling single-cell sequencing staining stress-related gene subset TNF-α transcriptome sequencing Transmission unique Viral antigen viral clearance Viral load viral persistence virus widespread [DOI] 10.1128/mbio.03436-21 PMC 바로가기 [Article Type] Research Article
Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19Case Report Published on 2021-12-232022-10-31 Journal: Case Reports in Infectious Diseases [Category] COVID-19, [키워드] Adults Affect age Antibiotics Asymptomatic caused clinical condition coronavirus 2 Coronavirus disease 2019 COVID-19 death discharged home distress Enterocolitis gastrointestinal complication health condition hypothermia Infant Intensive intensive care unit Intervention majority management Mild morbidity and mortality NEC Neonate newborn infant NICU Older Patient Premature radiological respiratory resulting returned SARS-CoV-2 severe complication Support surgical symptomatic infections Transmission viral respiratory infection while with COVID-19 with mild disease [DOI] 10.1155/2021/1442447 PMC 바로가기 [Article Type] Case Report
Neuroradiological emergency consultations during the first year of the COVID-19 pandemicResearch Article Published on 2021-08-302022-10-30 Journal: Neurological Research and Practice [Category] COVID-19, [키워드] Affect age and gender Analysis analyzed Care change Computed tomography conditions conducted Consultations coronavirus COVID-19 COVID-19 pandemic COVID-19 testing declined distribution Effect Germany hospital incidence Infection measure NEC NECs not significant pandemic Patient reflect remained Result risk stroke supplementary material Transient ischemic attack Transmission university hospital Weekly with COVID-19 [DOI] 10.1186/s42466-021-00147-8 PMC 바로가기 [Article Type] Research Article
Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2 leading to universal blueprints for vaccine designs인공 지능은 백신 설계를 위한 보편적 청사진으로 이어지는 SARS-CoV-2의 면역원성 환경을 예측합니다.Article Published on 2020-12-232022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 변종, 신약개발, 유전자 메커니즘, 치료기술, 치료제, [키워드] acute respiratory syndrome coronavirus allele Analysis analyzed Antigen presentation Antigen processing and presentation Applied immunology approach artificial intelligence autoimmune responses Biotechnology broad spectrum caused Cell cells chance Combination Computational biology and bioinformatics coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Coverage COVID-19 Data integration database develop effective epitope Epitopes help HLA HLA haplotype HLA haplotypes HLA-A HLA-B HLA-DR homology host immune system hotspot human population identify immunization immunogenic immunology Immunotherapy individual input MHC class I MHC class II Mutation NEC nonsynonymous mutation Nonsynonymous mutations Novel coronavirus occurred pandemic predict predicted predictor Protein proteome reduce reduced Region respiratory robust SARS-CoV-2 SARS-CoV-2 mutations SARS-CoV-2 proteome sequence Sequence conservation severe acute respiratory syndrome coronavirus 2 statistically significant subset surface antigen T-cell epitope T-cell epitopes Vaccine Vaccine design Vaccines Viral Virtual drug screening virus [DOI] 10.1038/s41598-020-78758-5 PMC 바로가기 [Article Type] Article