German nation-wide in-patient treatment of abdominal aortic aneurysm—trends between 2005 and 2019 and impact of the SARS-CoV-2 pandemicarticle Published on 2023-08-292024-09-05 Journal: CVIR Endovascular [Category] update2024, [키워드] Abdominal aortic aneurysm COVID-19 pandemic and AAA Epidemiological changes in AAA treatment EVAR Ruptured abdominal aortic aneurysm [DOI] 10.1186/s42155-023-00389-4 PMC 바로가기 [Article Type] article
Protocol for the Metformin Aneurysm Trial (MAT): a placebo-controlled randomised trial testing whether metformin reduces the risk of serious complications of abdominal aortic aneurysm메트포르민 동맥류 시험 프로토콜(MAT): 메트포르민이 복부 대동맥류의 심각한 합병증 위험을 감소시키는지 여부를 테스트하는 위약 대조 무작위 시험Study Protocol Published on 2021-12-272022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] Abdominal aortic aneurysm Alpha Aneurysm aneurysms Antibiotics aortic aneurysm Asymptomatic benefit blood pressure cardiovascular event Cell clinical COVID-19 pandemic defined diabetes double-blind drug therapy event events Evidence evidence of growth include inhibitor International life mast cell medication metformin metformin XR Mortality Multiple observational studies observational study outcome overcome parallel-group participant Patient Placebo placebo-controlled placebo-controlled trial potential participant Primary outcome progression proportion Quality of life randomised randomised controlled trial Randomised trial receive reduce reduced required risk rupture secondary Secondary outcomes serious complication single-blind surgical therapy Trial Trial registration trials unique [DOI] 10.1186/s13063-021-05915-0 PMC 바로가기 [Article Type] Study Protocol
ACTION-1: study protocol for a randomised controlled trial on ACT-guided heparinization during open abdominal aortic aneurysm repairACTION-1: 개방 복부 대동맥류 수리 중 ACT 유도 헤파린 처리에 대한 무작위 대조 시험 연구 프로토콜Study Protocol Published on 2021-09-192022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 30-Day mortality A significant reduction Abdominal aortic aneurysm Activated clotting time Admission Aneurysm Aneurysmal anticoagulation aortic aneurysm applied benefit bleeding blind Blood blood loss caused Clotting time Complication complications contrary data set Date decrease development disease dose eligible Endpoint enrolment EudraCT Europe evaluate exclusion criteria expected Germany GRADE Grade 1 healthy healthy volunteers heparin Hospital stay in-hospital mortality incidence Inclusion increase International less major bleeding Mesenteric artery Mortality Netherland Netherlands open Open repair operation Patient patients phase primary efficacy endpoint protocol Public randomised randomised controlled trial Randomized RCT re-operation reached recruitment reduce Registration repair report research and development Sample size secondary secondary outcome Sponsor Standard Standard of care Study protocol superior mesenteric artery supplementary material Support target TEC the patient Treatment Trial Trial registration undergo Vascular surgery [DOI] 10.1186/s13063-021-05552-7 PMC 바로가기 [Article Type] Study Protocol
Peripheral Artery Disease and Abdominal Aortic Aneurysm: The Forgotten Diseases in COVID-19 Pandemic. Results from an Observational Study on Real-World ManagementObservational Study Published on 2021-06-292022-10-04 Journal: Medicina [Category] MERS, SARS, 임상, [키워드] Abdominal aortic aneurysm analyzed aortic aneurysm Artery benefit cardiovascular risk COVID-19 COVID-19 pandemic disease drug Follow-up High-risk patients higher risk impacted LDL limitations Lipid lipid profile low-density management material Modification Mortality objective offer Patient patients peripheral Peripheral artery disease profile reducing required Result risk risk reduction Surveillance survival targets the mean therapeutic target therapy treated unit were recorded [DOI] 10.3390/medicina57070672 PMC 바로가기 [Article Type] Observational Study
Modelling the impact of changes to abdominal aortic aneurysm screening and treatment services in England during the COVID-19 pandemicCOVID-19 전염병 동안 영국에서 복부 대동맥류 검사 및 치료 서비스에 대한 변화의 영향 모델링Research Article Published on 2021-06-152022-09-12 Journal: PLoS ONE [Category] MERS, 진단, [키워드] AAAs Abdominal aortic aneurysm Aneurysm aneurysms aortic aneurysm Attendance change Cohort COVID-19 COVID-19 pandemic death deaths doubling effort Elective surgery England finding increase in Intervention investigated men MONITOR Mortality National Health Service NHS outcome outcomes patients reduce reduced reduction in rupture surgical Surveillance Suspension threshold Treatment was used [DOI] 10.1371/journal.pone.0253327 PMC 바로가기 [Article Type] Research Article
Abdominal emergencies in the geriatric patientReview Published on 2014-10-212024-09-02 Journal: International Journal of Emergency Medicine [Category] 대상포진, [키워드] Abdominal aortic aneurysm abdominal pain Appendicitis elderly mesenteric ischemia [DOI] 10.1186/s12245-014-0043-2 PMC 바로가기 [Article Type] Review
Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases기능성 IL6R 358Ala 대립유전자는 전통적인 IL-6 수용체 신호 전달을 손상시키고 다양한 염증성 질환의 위험에 영향을 미칩니다Research Article Published on 2013-04-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 358Ala Abdominal aortic aneurysm affecting allele analyzed aortic aneurysm approach Arthritis Asp358Ala association Asthma Atrial fibrillation Author balance benefit Cambridge BioResource causal variant CD4+ T cell CD4+ T cells CHD Chronic diseases circulating cleavage clinical trial clinical trials common diseases complex complex diseases Concentration Control copy Coronary heart disease Critical cytokine diabete diabetes etiology Evidence expression functional Genetic genetic association Genetic variation heart disease human disease identify IL-6 IL-6 receptor IL-6 signaling IL-6R IL-6R signaling IL-6R signaling pathway IL6R Immune cell immune cells impairment implicated implication increase increase in independent Inflammatory Inflammatory responses influence interleukin interleukin-6 isoform mechanism membrane-bound molecular mechanism monocyte Monocytes mononuclear cell mononuclear cells Non-synonymous nucleotide Patient PBMCs Peripheral blood Peripheral blood mononuclear cells Phosphorylation polymorphism Population protein level protein levels RA reduce reduced reduction regulated Regulation rheumatoid arthritis risk rs2228145 Signaling sIL-6R single nucleotide Single nucleotide polymorphism soluble IL-6R Stat1 STAT3 Stimulation suggested surface expression surface receptor susceptibility T cells T1D therapeutic intervention therapy These data Transcription transcription factor transcription factors translate Treatment response Type 1 diabetes variant Variation Volunteer [DOI] 10.1371/journal.pgen.1003444 PMC 바로가기 [Article Type] Research Article