C-reactive protein – My perspective on its first half century, 1930-1982article Published on 2023-03-312024-09-01 Journal: Frontiers in immunology [Category] 폐렴구균 감염증, [키워드] acute phase response C-reactive protein complement phagocytosis Rockefeller Institute [Article Type] article
The human host response to monkeypox infection: a proteomic case series studyArticle Published on 2022-11-082022-11-16 Journal: EMBO Molecular Medicine [Category] 유전자 메커니즘, [키워드] acute phase response Applying Biomarker case sery CFHR1 complement correlation COVID-19 disease severity Diseases endemic area healthy controls Host host response human host Infection Monkeypox virus outbreak overlap Patient plasma plasma protein Protein Proteins proteome proteomic proteomics provided Research similarities suggested suppressed the disease viral infection [DOI] 10.15252/emmm.202216643 PMC 바로가기
Sex-dependent characteristics of Neuro-Long-COVID: Data from a dedicated neurology ambulatory serviceShort communication Published on 2022-10-012022-10-05 Journal: Journal of the neurological sciences [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute COVID-19 acute phase response acute respiratory symptom age approach brain fog Characteristics Clinical data Cluster collected conducted demographic Dyspnea feature female headache immune response individuals Infection joint large sample long-COVID male males neurological no significant difference no significant differences offer PACS Pain palpitation Pathogenesis Patient Prevalence Respiratory failure Retrospective study SARS-CoV-2 Sex Sex difference significant difference Standard deviation subgroup analysis Support Symptom Symptoms the mean two groups Ventilation while [DOI] 10.1016/j.jns.2022.120355 [Article Type] Short communication
Biomarkers for iron metabolism among patients hospitalized with community-acquired pneumonia caused by infection with SARS-CoV-2, bacteria, and influenzaSARS-CoV-2, 박테리아 및 인플루엔자 감염으로 인한 지역사회획득 폐렴으로 입원한 환자의 철 대사에 대한 바이오마커Article Published on 2022-09-012022-09-11 Journal: Apmis [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute phase response Admission alteration analyzed Bacteria Bacterial Biomarker Biomarkers blood sample Blood samples C-reactive protein caused collected community-acquired pneumonia COVID-19 cross-sectional cross-sectional study CRP CRP level erythroferrone etiology evaluate ferritin hepcidin hospitalized patients Infection infection with SARS-CoV-2 Influenza influenza infection Influenza virus investigated IQR iron Iron metabolism median metabolism Patient patients hospitalized patients with SARS-CoV-2 Pneumonia Protein receptor recruited SARS-CoV-2 SARS-COV-2 infection severe COVID-19 Transferrin [DOI] 10.1111/apm.13259 PMC 바로가기 [Article Type] Article
Organ-specific host differential gene expression analysis in systemic candidiasis: A systems biology approach전신 칸디다증에서 기관 특이적 숙주 차등 유전자 발현 분석: 시스템 생물학 접근법Article Published on 2022-08-012022-09-11 Journal: Microbial pathogenesis [Category] 유전자 메커니즘, [키워드] acquisition Activation acute phase response Analysis approach C. albicans can be used Candida Candida albican Candida albicans Candidemia candidiasis Clinical management Co-infection Complication coronavirus disease COVID-19 COVID-19 infections COVID-19 mortality Critical Defense defense mechanisms develop Differential gene expression differentially expressed gene Differentially expressed genes down-regulated drug effector cells event fungal infections hospital Host hub genes human gene human genes Immune cell immune cells immune response immune responses Infection Interaction invasive involved iron kidney leukocyte liver lymphocyte mechanisms molecular mycotic infection mycotic infections occur organ organ-specific organs pathway proliferation protocol recruitment research finding risk Scientific community severe COVID-19 infections sluggish spleen Surveillance systemic Candidiasis Systems biology therapeutic therapy yeast [DOI] 10.1016/j.micpath.2022.105677 PMC 바로가기 [Article Type] Article
Association of cardiometabolic microRNAs with COVID-19 severity and mortalityCOVID-19 중증도 및 사망률과 심혈관 대사성 microRNA의 연관성Fast-Track Original Article Published on 2022-02-102022-09-10 Journal: Cardiovascular Research [Category] 바이오마커, [키워드] acute phase acute phase response age association Biomarkers Blood BMI candidate Candidates cardiometabolic Cell cell activation Chain Reaction circulating miRNA circulating miRNAs Cohort combinations coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 severity D-dimer determine differentially expressed endothelial healthy control healthy controls hepatocyte ICU intensive care lead liver longitudinal samples marker microRNA MicroRNAs Mild miR-122 miRNA miRNAs moderate Mortality Multiorgan myeloperoxidase Myocyte neutrophil neutrophil count neutrophil counts neutrophil degranulation outcome parameter patients performed plasma Platelet polymerase chain polymerase chain reaction positive predictor Protein proteomics proteomics data Quantitative reduced reflect reverse transcription reverse transcription quantitative polymerase chain reaction RNA-Seq SARS-CoV-2 selected severity tissue tissue injury Trajectories troponin with COVID-19 [DOI] 10.1093/cvr/cvab338 PMC 바로가기 [Article Type] Fast-Track Original Article
An Immunomodulatory Transcriptional Signature Associated With Persistent Listeria Infection in HepatocytesOriginal Research Published on 2021-11-102023-08-30 Journal: Frontiers in Cellular and Infection Microbiology [Category] E형 간염, [키워드] acute phase response cholesterol Innate immunity interferon Listeria monocytogenes liver persistence transcriptomics [DOI] 10.3389/fcimb.2021.761945 PMC 바로가기 [Article Type] Original Research
Persistent endotheliopathy in the pathogenesis of long COVID syndrome장기 코로나 증후군의 발병기전에서 지속되는 내피병증Brief Report Published on 2021-09-122022-09-10 Journal: Journal of thrombosis and haemostasis : JTH [Category] MERS, SARS, 바이오마커, [키워드] 95% CI Activation acute phase acute phase response addition Antigen autopsy studies autopsy study Biomarker breathlessness change comorbid patients contribute Control convalescent convalescent COVID‐19 correlated COVID COVID‐19 COVID‐19 patient COVID‐19 patients elevated Endothelial cell endothelial cell (EC) activation endotheliopathy Exercise Tolerance factor VIII fatigue Hospitalization immunothrombosis independent independent of Long COVID mechanism median NETosis objective Older parameter Pathogenesis Patient persistent plasma propeptide prothrombotic raise reported Result SARS‐CoV‐2 infection significantly significantly shorter sustained Symptom syndrome thrombin thrombomodulin Tolerance von Willebrand factor vWF were assessed [DOI] 10.1111/jth.15490 PMC 바로가기 [Article Type] Brief Report
Mass Spectrometric Analysis of Urine from COVID-19 Patients for Detection of SARS-CoV-2 Viral Antigen and to Study Host ResponseSARS-CoV-2 바이러스 항원 검출 및 숙주 반응 연구를 위한 COVID-19 환자의 소변 질량 분광 분석Article Published on 2021-07-022022-09-11 Journal: Journal of Proteome Research [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] acute phase response Affect alteration Amino acid amino acid transporter Analysis approach body fluid body fluids Brain capture Chain Reaction complement complement system coronavirus COVID-19 COVID-19 negative COVID-19 patient COVID-19 patients Culture detect detection diagnosed Glucose immune response in urine Infection involved Kidney function kidneys liver Lungs mass mass spectrometry microbial Nasopharyngeal swab nasopharyngeal swabs NPHS2 nucleocapsid protein organ Pathogenesis pathogenesis of COVID-19 peptide peptides polymerase chain polymerase chain reaction positive Protein proteome proteomic proteomics public health Quantitative quantitative proteomic analysis Regulation renal response reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 positive individual SARS-CoV-2 positive individuals SLC36A2 SLC5A10 sodium subset transcriptase Urine Viral Viral antigen viral antigens Viral RNA virus were used [DOI] 10.1021/acs.jproteome.1c00391 PMC 바로가기 [Article Type] Article
Longitudinal proteomic profiling provides insights into host response and proteome dynamics in COVID-19 progression세로 프로테옴 프로파일링은 COVID-19 진행에서 숙주 반응 및 프로테옴 역학에 대한 통찰력을 제공합니다Article Published on 2021-06-012022-09-11 Journal: Proteomics [Category] MERS, 바이오마커, 유전자 메커니즘, [키워드] acute phase response biological processe biological processes BNC2 collected coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 progression degranulation Disease progression expand high risk host response humoral immune response identify IGLV3-19 interferon involved Keywords lipid metabolism longitudinal longitudinal change longitudinal changes marker metabolism non-severe patients Patient patients with COVID-19 performed Platelet Potential biomarker potential biomarkers Prognosis prognostic prognostic indicator progressed progression Protein proteome proteomic proteomics provide Real-time monitoring SARS-COV-2 infection sera serum severe COVID-19 severity Support the disease [DOI] 10.1002/pmic.202000278 PMC 바로가기 [Article Type] Article