Inhaled nitric oxide as temporary respiratory stabilization in patients with COVID-19 related respiratory failure (INOCOV): Study protocol for a randomized controlled trialCOVID-19 관련 호흡 부전(INOCOV) 환자의 일시적인 호흡 안정화로서 흡입된 산화질소: 무작위 대조 시험을 위한 연구 프로토콜Article Published on 2022-05-272022-09-11 Journal: PLoS ONE [Category] 임상, [키워드] Acute respiratory failure adjunct airway anaesthesia blinded Blood cause of death COVID-19 death deoxygenated described End-Expiratory Pressure EudraCT fraction global public health High-flow oxygen Hypoxemia hypoxia Inhaled initial intubation life-threatening lung Lungs management margin measure mechanical ventilation nitric oxide no difference null hypothesis oxygen oxygen saturation pandemic Patient patients with COVID-19 PEEP pharmacological Positive end-expiratory pressure predominant preoxygenation primary outcome measure protocol Randomized Randomized controlled trial reduce Respiratory failure safety margin sequence severe hypoxia Shunt SpO2 Standard of care Trial Two-arm Ventilation WHO [DOI] 10.1371/journal.pone.0268822 PMC 바로가기 [Article Type] Article
Updates for Health Providers on Monoclonal Antibodies for COVID-19: Less Promising Adjunct and Never an Alternative to VaccinationsCOVID-19에 대한 단일 클론 항체에 대한 의료 제공자를 위한 업데이트: 덜 유망한 보조제 및 백신에 대한 절대 대안 없음Editorial Published on 2022-05-012022-09-12 Journal: The American journal of medicine [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] adjunct [DOI] 10.1016/j.amjmed.2021.12.019 PMC 바로가기 [Article Type] Editorial
The use of standardized Brazilian green propolis extract (EPP-AF) as an adjunct treatment for hospitalized COVID-19 patients (BeeCovid2): a structured summary of a study protocol for a randomized controlled trial입원한 COVID-19 환자(BeeCovid2)의 보조 치료제로 표준화된 브라질 녹색 프로폴리스 추출물(EPP-AF)의 사용: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Article Published on 2022-04-042022-09-11 Journal: Trials [Category] 임상, [키워드] 1:1 2019 coronavirus disease ACE2 acute COVID-19 Acute kidney injury adjunct Administered adults hospitalized Affect affected age anti-inflammatory agents association Bacterial balloon pump Brazil Cancer patients chronic disease Chronic diseases Chronic kidney disease clinical study conducted coronavirus disease COVID-19 demonstrated diagnosis of COVID-19 double-blinded ECMO Effectiveness Evidence experimental evidence extracorporeal membrane oxygenation Fungal infection groups heart failure HIV patients Hospital stay hospitalized COVID-19 patient hospitalized patients immunoregulation Immunosuppression impacts impossibility include Infection intra-aortic balloon pump Kidney disease Liver disease mechanical ventilation medication moderate moderate to severe outcome PAK1 PAK1 blocker pandemic Patient patients hospitalized Placebo placebo-controlled clinical study pregnant women Primary outcome Propolis protocol randomization Randomized Randomized controlled trial receive reducing renal replacement therapy replacement therapy secondary Secondary infection Secondary outcomes severe liver disease Spread standard care Study protocol Symptom targets TMPRSS2 Treatment Trial vasoactive drugs with COVID-19 [DOI] 10.1186/s13063-022-06176-1 PMC 바로가기 [Article Type] Article
Analysis of COVID-19 Risk Following a Ring Vaccination Intervention to Address SARS-CoV-2 Alpha Variant Transmission in Montreal, Canada캐나다 몬트리올에서 SARS-CoV-2 알파 변종 전파를 해결하기 위한 링 백신 개입 후 COVID-19 위험 분석Research Published on 2022-02-112022-09-10 Journal: JAMA Network Open [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] 95% CI address adjunct age Alpha Alpha variant analyzed association Canada children close contact cohort study confirmed case confirmed cases Contact contact with control group Coverage COVID-19 COVID-19 incidence COVID-19 infection COVID-19 vaccine defined disease risk dose Epidemiology exposure finding group groups highest immunization immunization strategies immunization strategy immunized implementation Importance Infection initial Intervention intervention group introduced Local mass immunization measure Montreal Montreal, Canada mRNA vaccine objective outbreak pandemic parent parents participant Point reached receive reduction in Relevance respiratory respiratory viruses Result Ring risk risk of COVID-19 risk ratio SARS-CoV-2 SARS-CoV-2 transmission SARS-CoV-2 variant SARS-CoV-2 variants School setting significantly higher Spread Transmission vaccination Vaccine variant [DOI] 10.1001/jamanetworkopen.2021.47042 PMC 바로가기 [Article Type] Research
Comparison of longitudinal trends in self-reported symptoms and COVID-19 case activity in Ontario, Canada캐나다 온타리오주에서 자가 보고된 증상 및 COVID-19 사례 활동의 종단적 추세 비교Research Article Published on 2022-01-112022-09-12 Journal: PLoS ONE [Category] SARS, 진단, [키워드] adjunct analyzed can be used Canada changes in collected correlation Coverage COVID-19 COVID-19 case COVID-19 cases demographic characteristics determine diagnostic discrepancy enterovirus explain group individual Laboratory Laboratory testing laboratory-confirmed less limitation online tool Other respiratory viruses Outbreaks PCR-confirmed COVID-19 population surveillance positive correlation proportion reflected respiratory virus Result rhinovirus seasonal self-reported symptom Strong Surveillance Symptom Transmission [DOI] 10.1371/journal.pone.0262447 PMC 바로가기 [Article Type] Research Article
Beneficial effects of novel aureobasidium pullulans strains produced beta-1,3-1,6 glucans on interleukin-6 and D-dimer levels in COVID-19 patients; results of a randomized multiple-arm pilot clinical study새로운 아우레오바시디움 풀루란스 균주의 유익한 효과는 코로나19 환자의 인터루킨-6 및 D-이량체 수준에 대한 베타-1,3-1,6 글루칸을 생성했습니다. 무작위 다중군 파일럿 임상 연구 결과Randomized Controlled Trial Published on 2022-01-012022-09-11 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] SARS, 바이오마커, 임상, [키워드] adjunct Adjunct treatment Beta beta glucan Beta glucans Biomarker Biomarkers CD4 CD8 clinical study Coagulopathy Combination COVID-19 COVID-19 patients CRP cytokine Cytokine storm D-dimer D-dimer level D-dimer values decrease Effect ESR group groups IL-6 Immuno-modulation. increase in interleukin-6 LCR management Mortality NLR no difference Patient positive COVID-19 produced Randomized randomly divided recruited RT-PCR significantly Standard standard treatment steadily decreased strain subject syndrome T cell three group three groups Treatment Ventilation yeast [DOI] 10.1016/j.biopha.2021.112243 PMC 바로가기 [Article Type] Randomized Controlled Trial
The US COVID-19 Trends and Impact Survey: Continuous real-time measurement of COVID-19 symptoms, risks, protective behaviors, testing, and vaccination미국 COVID-19 동향 및 영향 조사: COVID-19 증상, 위험, 보호 행동, 테스트 및 예방 접종에 대한 지속적인 실시간 측정Comparative Study Published on 2021-12-132022-09-12 Journal: Proceedings of the National Academy of Sciences of [Category] 진단, [키워드] adjunct analyses comparison Comparisons conducted content Continuous COVID COVID-19 COVID-19 epidemic COVID-19 symptoms cross-sectional example Facebook facilitate health priorities help Impact impacts information Key priorities mental health offer operation outcome pandemic Policy preventive measures Protective public health question random Random sample reported respond response responses SARS-CoV2 Significance subject Surveillance survey Symptoms the United State trend unique United States vaccination [DOI] 10.1073/pnas.2111454118 PMC 바로가기 [Article Type] Comparative Study
Colchicine, COVID-19 and hematological parameters: A meta-analysis콜히친, COVID-19 및 혈액 학적 파라미터 : 메타 분석Meta-Analysis Published on 2021-12-012022-08-31 Journal: Journal of Clinical Laboratory Analysis [Category] MERS, 바이오마커, [키워드] adjunct Anti-inflammatory anti-inflammatory properties Biomarker C-reactive protein C-reactive protein (CRP clinical and laboratory parameters ClinicalTrials Colchicine colchicine group conducted COVID-19 COVID-19 infection COVID-19 patients COVID-19 treatment CRP D-dimer D-dimer value D-dimer values database databases determine Direct effect size Efficacy Elsevier Google Scholar hematological Inflammatory Inflammatory biomarker inflammatory biomarkers item Laboratory laboratory parameter Lactate lactate dehydrogenase LDH Meta-analysis moderate-to-severe COVID-19 patients morbidity and mortality Other Patient post treatment PRISMA Protein reducing reduction reductions in reported Reporting review SAGE SARS-CoV-2 Science Science Direct searched significant reductions SMD Treatment Trial trials Web of Science [DOI] 10.1002/jcla.24057 PMC 바로가기 [Article Type] Meta-Analysis
Prevention of SARS-CoV-2 (COVID-19) transmission in residential aged care using ultraviolet light (PETRA): a two-arm crossover randomised controlled trial protocol자외선 (PETRA)을 사용한 주거 노화 치료에서 SARS-COV-2 (COVID-19) 전송 예방 : 2ARM 크로스 오버 무작위 대조 시험 프로토콜Study Protocol Published on 2021-09-172022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 임상, 치료기술, [키워드] addition adjunct baseline benefit Care care providers changes in Characteristics clinical Complication conducted Contact contribute Controlled trial correlation COVID-19 COVID-19 outbreak crossover detect determine droplet transmission effective Efficacy Evidence facility focus followed by genomic germicidal Germicidal ultraviolet light hand hygiene Health care quality hospitalisation hygiene incidence rate incidence rates include Infection infection control infection rate initial Intervention Laboratory measure Measures morbidity and mortality Mortality multicentre New Other respiratory viruses outcome partnership pathogen transmission Prevent prevention Primary outcome protocol randomised randomised controlled trial rate ratio reduce reducing reduction in Registered registry Residential aged care respiratory Respiratory illness respiratory illnesses respiratory infection respiratory infections respiratory viral respiratory virus Respiratory virus infection respiratory viruses risk Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission secondary Secondary outcomes separated severe disease social distancing South Spread symptomatic symptomatic infection Transmission transmission of SARS-CoV-2 Two-arm ultraviolet ultraviolet light Viral vulnerable population zone [DOI] 10.1186/s12879-021-06659-7 PMC 바로가기 [Article Type] Study Protocol
SARS-CoV-2 serology: Validation of high-throughput chemiluminescent immunoassay (CLIA) platforms and a field study in British ColumbiaSARS-CoV-2 혈청학: 브리티시컬럼비아에서 고처리량 화학발광 면역분석(CLIA) 플랫폼 및 현장 연구 검증Article Published on 2021-09-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 진단, 치료기술, [키워드] Abbott addition adjunct Antibody testing assays automated Care chemiluminescent immunoassay CLIA collected COVID-19 demonstrated diagnose diagnoses DiaSorin Disease prevalence Elecsy evaluated field Infection LIAISON molecular Negative predictive value Ortho Vitros outbreak Outbreak investigation outbreak investigations PCR PCR testing performed platform Positive predictive value positive predictive values post-symptom onset PPV predictive values Prevalence required Roche S1/S2 SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody testing sensitivities sensitivity Sensitivity and specificity serologic serologic testing serology Siemen Siemens Specificities tested Total vaccine response validation validation study [DOI] 10.1016/j.jcv.2021.104914 PMC 바로가기 [Article Type] Article