A Handle on Mass Coincidence Errors in De Novo Sequencing of Antibodies by Bottom-up Proteomicsarticle Published on 2024-06-272024-09-05 Journal: Journal of Proteome Research [Category] update2024, [키워드] alignment antibodies de novo sequencing isobaric mass spectrometry sequence assembly [DOI] 10.1021/acs.jproteome.4c00188 PMC 바로가기 [Article Type] article
Enabling Artificial Intelligence for Genome Sequence Analysis of COVID-19 and Alike VirusesCOVID-19 및 유사 바이러스의 게놈 서열 분석을 위한 인공 지능 지원Article Published on 2022-06-012022-09-11 Journal: Interdisciplinary sciences, computational life sci [Category] COVID19(2023년), SARS, 변종, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alignment amino acids Analysis antiviral drugs artificial artificial intelligence Behavior caused Classifier coronavirus 2 count COVID-19 Data analysis Data center data set DNA Ebola Enabling Frequency Genetic variant genetic variants genome sequence Genome sequence analysis Genome sequences Health help information intelligence machine machine learning MERS Middle East respiratory syndrome nucleotide nucleotides pandemic of COVID-19 recent Repository researcher SARS-CoV-2 sequence Sequence analysis Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus similarity Support SVM SVM. syndrome Vaccines virus virus genome viruses [DOI] 10.1007/s12539-021-00465-0 PMC 바로가기 [Article Type] Article
Monitoring of alcohol-based hand rubs in SARS-CoV-2 prevention by HS-GC/MS and electrochemical biosensor: A survey of commercial samplesHS-GC/MS 및 전기화학적 바이오센서에 의한 SARS-CoV-2 예방의 알코올 기반 손 문지름 모니터링: 상업용 샘플 조사Article Published on 2022-05-302022-09-11 Journal: Journal of pharmaceutical and biomedical analysis [Category] COVID19(2023년), SARS, 치료기술, [키워드] acidification addition agency alcohol Alcohol-based hand rubs alignment ANOVA ANOVA test approach average Chromatography comparable Control coronavirus 2 correlation COVID-19 data set determine diffusion electrochemical biosensor ethyl alcohol evaluated gas chromatography Gas chromatography. hand hygiene Health highlighting house hygiene identify indicated indication indications isopropyl alcohol limit limit of detection LoQ mass mass spectrometry methyl alcohol monitoring parameter propyl alcohol provided quantification reported respiratory Result SARS-CoV-2 screening method severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spectrometry statistically tested were assessed widespread [DOI] 10.1016/j.jpba.2022.114694 PMC 바로가기 [Article Type] Article
Advancing clinical trials in nursing homes: A proposed roadmap to success요양원에서의 임상 시험 진행: 성공을 위한 제안된 로드맵Article Published on 2022-05-012022-09-11 Journal: Geriatric nursing (New York, N.Y.) [Category] 임상, [키워드] Administered Advancing alignment American build Care center clinical Clinical research clinical trial clinical trials COVID-19 develop Diversity effective Effectiveness Efficacy effort foster group Health Health care IMPROVE Independence initiative Long-term care Nursing nursing home nursing homes pandemic Panel pathway recommendation recommendations Research researcher researchers study population supported System Treatment [DOI] 10.1016/j.gerinurse.2022.02.005 PMC 바로가기 [Article Type] Article
Impact of SARS-CoV-2 Mutations on PCR Assay Sequence AlignmentSARS-CoV-2 돌연변이가 PCR 분석 시퀀스 정렬에 미치는 영향Article Published on 2022-04-282022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] alignment Analysis analyzed assays biosurveillance blind Chain Reaction clinical samples COVID-19 creating diagnosis of COVID-19 diagnostic diagnostics dominant Evidence evidence of failure False negative false negatives functional consequence functional consequences Genome genomic RNA growth highlight identify Impact in silico in viral molecular test Molecular tests Mutation mutations occurred pandemic PCR PCR assay PCR assays polymerase chain polymerase chain reaction preserved proportion Real-time monitoring Real-Time Reverse Transcription Polymerase Chain Reaction Region reverse transcription RT-PCR SARS-CoV-2 SARS-CoV-2 sequences Sensitivity and specificity sequence sequence identity Sequencing signature statistically sustained therapeutic unique Vaccine variant Viral viral genomes whole genome whole genome sequence Whole genome sequencing [DOI] 10.3389/fpubh.2022.889973 PMC 바로가기 [Article Type] Article
Detection of COVID-19 using multimodal data from a wearable device: results from the first TemPredict Study웨어러블 장치의 멀티 모달 데이터를 사용한 Covid-19의 감지 : 첫 번째 온 프레드 틱 연구 결과Article Published on 2022-03-022022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI Accuracy age Algorithm alignment antibody AUC average Biotechnology consumer COVID-19 COVID-19 disease Critical detection diagnostic Diagnostic markers diagnostic testing disease disease transmission Early detection feature finding helping highlight identify Including individual medical intervention Medical research Metrics participant Participants PCR testing physiological Population Predictive markers promise questionnaire data recognize reducing Ring ROC AUC SARS CoV SARS CoV-2 Scientific data selected self-isolate sensitivity Sex Signs and symptoms specificity subset temperature Variation [DOI] 10.1038/s41598-022-07314-0 PMC 바로가기 [Article Type] Article
Sharing Knowledge to an Entrant for Production Investment Confronting COVID-19: Incentive Alignment and Lose-Lose DilemmaCOVID-19에 직면한 생산 투자를 위해 참가자에게 지식 공유: 인센티브 조정 및 패소 딜레마Review Published on 2022-01-012022-09-11 Journal: Risk Analysis [Category] SARS, 치료제, [키워드] alignment benefit competing competition Competition and cooperation cooperation COVID-19 COVID-19 treatment develop dilemma Efficiency engage help identify Incentive incentive analysis inefficient information Investment knowledge knowledge sharing Medical devices Mild Production production investment. reduction sense Treatment two-dimensional Variability ventilator Volume [DOI] 10.1111/risa.13839 PMC 바로가기 [Article Type] Review
Embeddings from protein language models predict conservation and variant effectsArticle Published on 2021-12-302022-11-15 Journal: Human Genetics [Category] COVID19(2023년), SARS, 변종, [키워드] Algorithm alignment Amino acid analyses applied approach data set database deep deep learning Effect embedding entire sequence expand experiment fraction human proteins investigated language Local Logistic regression magnitude Model Multiple sequence alignment Nvidia Pearson correlation predict predicted prediction Probability Protein protein sequences Proteins proteome regions residue RTX SARS-CoV-2 variant scanning score sequence Sequence conservation significantly Spearman statistically supplementary material variant while [DOI] 10.1007/s00439-021-02411-y PMC 바로가기
Tracking SARS-CoV-2 Spike Protein Mutations in the United States (January 2020—March 2021) Using a Statistical Learning Strategy통계 학습 전략을 사용하여 미국에서 SARS-COV-2 스파이크 단백질 돌연변이 추적 (2020 년 1 월-2021 년 3 월)Article Published on 2021-12-212022-09-10 Journal: Viruses [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alignment Analysis analyzed applied approach complementary coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 D1118H eight false discovery rate functional genomic Genomic surveillance GISAID highlight homology homology modelling identify identifying L452R learning MONITOR mutations proportion Protein protein sequence protein structure q-value reference strain residue respiratory SARS-CoV-2 sequence severe acute respiratory syndrome Coronavirus spatiotemporal spike Spike protein Spike protein sequence statistical statistical learning strain Strains Strategy Substitution supported Surveillance temporal dynamics the United State United States unsupervised learning variant variants variants of concern variants of interest Viral viral residue variant VOCs VOIs was performed [DOI] 10.3390/v14010009 PMC 바로가기 [Article Type] Article
Jumper enables discontinuous transcript assembly in coronaviruses점퍼는 코로나바이러스에서 불연속 전사 조립을 가능하게 합니다.Article Published on 2021-11-182022-09-10 Journal: Nature Communications [Category] MERS, SARS, 유전자 메커니즘, 치료제, [키워드] alignment analyses Analysis assembly canonical classical conditions coronavirus develop discontinuous transcription drug response eukaryote eukaryotes expressed expression Gene Expression Genome informatics identify JUMPER likelihood MERS-CoV Nidovirale Nidovirales outperform predict produced reveal RNA polymerase RNA splicing RNA-dependent RNA polymerase SARS-CoV-1 SARS-CoV-2 Software subsequent supported transcript transcriptional change Transcriptional changes Transcriptome transcriptomes transcripts Treatment Viral Viral RNA viral RNA-dependent RNA polymerase virus viruses [DOI] 10.1038/s41467-021-26944-y PMC 바로가기 [Article Type] Article