Issues regarding COVID-19 in kidney transplantation in the ERA of the Omicron variant: a commentary by the ERA Descartes Working GroupArticle Published on 2022-09-222022-11-15 Journal: Nephrology, dialysis, transplantation : official p [Category] SARS, 변종, 치료제, [키워드] acute respiratory syndrome ambulatory patients Antiviral Antiviral agents antiviral drug Breakthrough infection Clinical practice concerning coronavirus coronavirus disease COVID-19 criteria Deceased depleting Developing dominant donors drug-to-drug interactions education Efficacy European group immunization Immunosuppression implementation Infection issue kidney kidney donation kidney transplant recipient kidney transplant recipients Kidney transplantation management omicron Prophylactic question raised recommendation risk SARS-CoV-2 Science severe disease shielding T cell transplantation Treatment treatment strategy vaccination variant widespread with COVID-19 working [DOI] 10.1093/ndt/gfac203 PMC 바로가기
A Randomized, Placebo-Controlled Clinical Trial of Bamlanivimab and Etesevimab Together in High-Risk Ambulatory Patients With COVID-19 and Validation of the Prognostic Value of Persistently High Viral Load코로나19 고위험 보행 환자를 대상으로 한 밤라니비맙과 에테세비맙의 무작위 위약 대조 임상 시험 및 지속적으로 높은 바이러스 부하의 예후 가치 검증Randomized Controlled Trial Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 임상, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age ambulatory ambulatory patient ambulatory patients antibody treatment applicability bamlanivimab baseline characterized clinical clinical status Cohort confidence interval coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 test Day death determine etesevimab expand first positive greater high risk Hospitalization infused Interim analyses interim analysis intravenously investigated load lower dose median median age Mild-to-moderate NCT04427501 occurred optimal dose outcome Patient persistently high viral load. phase Placebo placebo group receiving reduction in respiratory risk factor SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe COVID-19 Support the placebo group These data those receiving placebo Treatment Trial validation value variant Viral Viral load [DOI] 10.1093/cid/ciab912 PMC 바로가기 [Article Type] Randomized Controlled Trial
Thromboembolic events in COVID-19 ambulatory patients: An observational study about incidence, and thromboprophylaxis outcomesObservational Study Published on 2022-08-042022-10-05 Journal: PLoS ONE [Category] 임상, [키워드] age ambulatory patients Cohort Complication complications conducted COVID-19 defined described eight event FIVE Hemorrhagic hemorrhagic event high risk incidence LMWH management occurred outcome Patient prophylactic strategy rivaroxaban thromboembolic complication Thromboprophylaxis venous venous thromboembolic [DOI] 10.1371/journal.pone.0270195 PMC 바로가기 [Article Type] Observational Study
cfDNA as a surrogate marker for COVID-19 severity in patients with influenza-like symptoms with and without SARS-CoV-2 infections in general practice: a study protocol for a prospective cohort study일반적으로 SARS-CoV-2 감염이 있거나 없는 인플루엔자 유사 증상이 있는 환자에서 COVID-19 중증도에 대한 대리 표지자로서의 cfDNA: 전향적 코호트 연구를 위한 연구 프로토콜Article Published on 2022-06-162022-09-11 Journal: BMJ Open [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] (cfDNA ambulatory patient ambulatory patients Blood blood count Blood samples C-reactive protein C-reactive protein (CRP Cell Cell Biology cell-free DNA cfDNA Clinical course clinical parameter Clinical parameters Concentration concomitant symptoms correlation Course COVID-19 COVID-19 severity CRP death determine differential blood count differentiation erythrocyte sedimentation erythrocyte sedimentation rate Essen Ethical approval Ethics ethics committee examination finding flu-like symptom flu-like symptoms general medicine (see internal medicine) General practice identify Infection Influenza influenza-like symptom Influenza-like symptoms internal medicine International Laboratory lead longitudinal cohort study lung Lungs lymphocyte Lymphocyte count lymphocyte counts marker Molecular biology National oxygen oxygen saturation parameters Patient patients peer-reviewed Physicians Predictive Prognosis prospective cohort study questionnaire recruited registration number reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 patient SARS-CoV-2 patients sedimentation rate Study protocol Symptom temperature the disease Two-arm [DOI] 10.1136/bmjopen-2021-058647 PMC 바로가기 [Article Type] Article
Seroprevalence of IgG antibodies against SARS-CoV-2 – a serial prospective cross-sectional nationwide study of residual samples, Belgium, March to October 2020SARS-CoV-2에 대한 IgG 항체의 Seroprevalence - 잔류 샘플에 대한 연속 전향적 전국 횡단 연구, 벨기에, 2020년 3월~10월Article Published on 2022-03-012022-09-11 Journal: Eurosurveillance [Category] MERS, SARS, 진단, 치료기술, [키워드] age ambulatory patient ambulatory patients analysed Belgium COVID-19 credible interval cross-sectional detectable ELISA Epidemic epidemic waves epitope estimate Evolution exposure to fraction humoral Humoral immunity IgG antibodies IgG antibody lifted lockdown measure National performed resulting S1 protein SARS-CoV-2 SARS-CoV-2 S1 SARS-CoV-2 S1 epitope SARS-CoV-2 S1 protein SARS-CoV-2 seroprevalence sensitivity sera serial sero-survey Serologically Seroprevalence seroprevalence seroincidence. Seven Sex significant decrease stratified susceptibility the SARS-CoV-2 [DOI] 10.2807/1560-7917.ES.2022.27.9.2100419 PMC 바로가기 [Article Type] Article
Duration of viral shedding and culture positivity with postvaccination SARS-CoV-2 delta variant infections백신 접종 후 SARS-CoV-2 델타 변이체 감염으로 인한 바이러스 배출 및 배양 양성 기간Research Article Published on 2022-01-252022-09-10 Journal: JCI Insight [Category] 변종, 치료기술, [키워드] 24 hour 24 hours acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ambulatory patient ambulatory patients Asymptomatic Breakthrough infection breakthrough infections characterized Cohort collected coronavirus correlated COVID-19 Culture delta variant Duration early stage early stages Epidemiology evaluate greater individual Infection infections Infectious disease initial viral load Isolation likelihood nasal swab nasal swabs PCR PCR positivity postvaccination quantification Replication replication-competent virus resolution of symptoms respiratory SARS-CoV-2 SARS-CoV-2 delta SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 viral load severe acute respiratory syndrome Coronavirus Support symptom onset symptom resolution symptomatic symptomatic individual symptomatic individuals These data US CDC vaccination variant variants Viral viral culture viral load quantification viral shedding virus whole-genome sequencing [DOI] 10.1172/jci.insight.155483 PMC 바로가기 [Article Type] Research Article
Prevalence of SARS-CoV-2 Variants of Concern and Variants of Interest in COVID-19 Breakthrough Infections in a Hospital in Monterrey, MexicoSARS-COV-2 우려 변동의 유병률 및 멕시코 몬테레이에있는 병원에서 COVID-19 획기적인 감염에 대한 관심의 변형Observational Study Published on 2022-01-142022-09-10 Journal: Viruses [Category] SARS, 변종, 임상, 치료기술, [키워드] Administered ambulatory patient ambulatory patients AstraZeneca B.1.617.2 B.1.621 Breakthrough infection breakthrough infections CanSino case-control study Complete concern control group COVID-19 COVID-19 vaccines defined Delta Efficacy first dose hospital Hospitalization Hospitalized hospitalized patient hospitalized patients immunization increased risk inoculation interest Latin America Local Mexico mild COVID-19 symptom mild COVID-19 symptoms Mu occurred Patient patients Pfizer/BioNTech Prevalence public health SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants second dose Sinovac Surveillance therapy vaccination Vaccine vaccine administration vaccine breakthrough infection vaccine breakthrough infections Vaccines variant of concern VoC VOCs VOIs was performed whole-genome sequencing [DOI] 10.3390/v14010154 PMC 바로가기 [Article Type] Observational Study
Ambulatory care management of 69 patients with acute severe ulcerative colitis in comparison to 695 inpatients: insights from a multicentre UK cohort study695명의 입원 환자와 비교하여 급성 중증 궤양성 대장염 환자 69명의 외래 치료 관리: 영국 다기관 코호트 연구의 통찰력Multicenter Study Published on 2022-01-012022-09-11 Journal: BMJ open gastroenterology [Category] SARS, 치료기술, [키워드] acceptability age ambulatory Ambulatory care ambulatory patient ambulatory patients Analysis Aside bowel Care Cohort cohort study cohorts colectomy collected Corticosteroid COVID-19 criteria detect Diagnosis discharged disease disease phenotype Effectiveness Eligible patients evaluated flexible flexible sigmoidoscopy Follow-up Health Service health service research hospital Hospital admission hospital management hospitalised IBD IBD clinical index Inflammatory Inflammatory bowel disease intravenous less management Mortality multicentre no significant difference no significant differences outcome outcome measure Pathways Patient patients treated performed phenotype physician post-hoc analysis Primary outcome PROTECT readmission recruited registration number required rescue secondary secondary outcome Secondary outcomes Steroids Stool culture subsequent surgery surgery for IBD therapy Treatment Treatment outcome ulcerative colitis used data [DOI] 10.1136/bmjgast-2021-000763 PMC 바로가기 [Article Type] Multicenter Study
Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19경증 또는 중등도의 Covid-19에서 밤라니비맙과 에테세비맙Clinical Trial Published on 2021-10-072022-09-12 Journal: The New England Journal of Medicine [Category] MERS, SARS, 신약개발, 임상, 진단, [키워드] 1:1 95% CI 95% confidence interval accelerated acute respiratory syndrome Administered age ambulatory patient ambulatory patients assigned bamlanivimab baseline clinical status Cohort Combination complications coronavirus death defined develop Diagnosis Disease progression etesevimab greater high risk Hospitalization Immunity incidence increased risk Infection investigator Laboratory limit log medical condition Mild moderate NCT04427501 Neutralizing occurred passive immunity Patient patients phase 3 trial Placebo Primary outcome progression provide randomization Randomly receive reduction risk SARS-CoV-2 severe coronavirus disease severe disease single intravenous infusion the patient the placebo group the SARS-CoV-2 Treatment Trial Viral load women [DOI] 10.1056/NEJMoa2102685 PMC 바로가기 [Article Type] Clinical Trial
Lung Ultrasound Examination in Patients with SARS-CoV-2 Infection: Multicenter StudyArticle Published on 2021-07-232022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] age ambulatory patients average Care characterized chest sonography Computed tomography consolidations contributed COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients diagnostic Diagnostic method examination High-resolution hospitalized patient hospitalized patients HRCT indicated infected patients interstitial interstitial pneumonia lung LUS males measure multicenter study Older Patient patients Pneumonia positively correlated SARS-CoV-2 Sensitivity and specificity significantly more syndrome Ultrasound was performed [DOI] 10.3390/jcm10153255 PMC 바로가기 [Article Type] Article