Impaired STING Activation Due to a Variant in the E3 Ubiquitin Ligase AMFR in a Patient with Severe VZV Infection and Hemophagocytic Lymphohistiocytosis심각한 VZV 감염 및 혈구탐식 림프조직구증을 앓고 있는 환자에서 E3 유비퀴틴 리가제 AMFR의 변이에 의한 STING 활성화 손상Article Published on 2024-01-262024-08-16 Journal: Journal of Clinical Immunology [Category] 대상포진, [키워드] AMFR HLH interferon ISG STING ubiquitin ligase VZV.
LZP is required for hepatic triacylglycerol transportation through maintaining apolipoprotein B stabilityLZP는 아포지단백 B의 안정성을 유지하여 간의 트리아실글리세롤 수송에 필요합니다.Research Article Published on 2021-02-162022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence AMFR ApoB Apolipoprotein B assembly Atherosclerosis Author Blood characterized cholesterol components conserved contribute decrease deficiency Degradation disease domain E3 ligase E3 ubiquitin ligase elevated Endoplasmic reticulum enhancement expressed Extracellular Fatty liver fatty liver disease function Golgi apparatus hepatic lipid hepatic steatosis homeostasis Human inhibited knowledge lipid metabolism lipoprotein Lipoproteins liver low-density Low-density lipoprotein low-density lipoproteins Metabolic diseases metabolism mice molecular NAFLD nonalcoholic fatty liver Nonalcoholic Fatty Liver Disease obesity OIT3 organ Particle physiological Prevent Protein receptor receptors Regulation required reveal secreted secretion serum shown significantly stability TG level triacylglycerol Tumor tumor suppressors variety Very Low-Density Lipoproteins VLDL zona pellucida [DOI] 10.1371/journal.pgen.1009357 PMC 바로가기 [Article Type] Research Article