Clinical Evaluation of the XDR-LFC Assay for the Molecular Detection of Isoniazid, Rifampin, Fluoroquinolone, Kanamycin, Capreomycin, and Amikacin Drug Resistance in a Prospective CohortMycobacteriology and Aerobic Actinomycetes Published on 2023-02-092024-09-05 Journal: Journal of Clinical Microbiology [Category] update2024, [키워드] Amikacin Capreomycin drug susceptibility drug-resistant tuberculosis Fluoroquinolone isoniazid kanamycin lateral-flow cell Mycobacterium tuberculosis rifampin [DOI] 10.1128/jcm.01478-22 PMC 바로가기 [Article Type] Mycobacteriology and Aerobic Actinomycetes
Amikacin-loaded niosome nanoparticles improve amikacin activity against antibiotic-resistant Klebsiella pneumoniae strainsArticle Published on 2022-10-032022-11-16 Journal: World journal of microbiology & biotechnology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Amikacin analyzed antibiotic Antibiotic-resistance Antibiotics Bacteria Bacterial infection Bacterial infections calculated Cell cholesterol Concentration Coverage cytotoxicity drug resistance drug-resistant evaluated Gene Expression highest hospitalized patients IMPROVE inhibited Klebsiella Klebsiella pneumoniae less MBC MDR mechanism mRNA expression multi-drug resistant Niosome Niosome. occur positive ranged reduced SARS-CoV-2 significantly Spread stability strain Strains Toxicity Treatment were measured [DOI] 10.1007/s11274-022-03405-2 PMC 바로가기
Identification of novel transmembrane Protease Serine Type 2 drug candidates for COVID-19 using computational studiesResearch article Published on 2021-09-072022-10-05 Journal: Informatics in Medicine Unlocked [Category] 신약개발, [키워드] 3D structure acute respiratory syndrome Amikacin binding affinities build computational method Computational study conducted Coronavirus-2 COVID-19 docking docking score drug drug candidate Drug repurposing effective therapy enzyme exhibited functional Health homology homology modeling host cell identification identify in silico inhibit SARS-CoV-2 inhibition molecular dynamics outcomes pandemic SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection screened severity Spread TMPRSS2 transmembrane Type was performed [DOI] 10.1016/j.imu.2021.100725 [Article Type] Research article
Aminoglycosides as potential inhibitors of SARS-CoV-2 main protease: an in silico drug repurposing study on FDA-approved antiviral and anti-infection agentsSARS-CoV-2 주요 프로테아제의 잠재적 억제제로서의 아미노글리코사이드: FDA 승인 항바이러스제 및 항감염제에 대한 실리코 약물 용도 변경 연구Article Published on 2021-05-012022-08-31 Journal: Journal of infection and public health [Category] MERS, SARS, 신약개발, 치료제, [키워드] Amikacin Aminoglycoside Aminoglycosides anti-infection Antibiotics Antiviral approach binding cleaving clinical trials clinically complex COVID-19 docking Docking and simulation drug drug candidate drugs evaluate exhibited followed by free energy Free energy calculation Free energy calculations help hydrogen hydrogen bonds in silico in vitro in vivo inhibitor inhibitors of SARS-CoV-2 interactions iodixanol lead lowest M pro MD simulation MD simulations molecular molecular docking molecular dynamics Neomycin overcome pandemic protease required residues rutin salt salt bridges SARS-CoV-2 screened Simulation Spread streptomycin suggested tobramycin troxerutin van der Waal van der Waals interactions Virtual screening [DOI] 10.1016/j.jiph.2021.01.016 PMC 바로가기 [Article Type] Article
MANAGEMENT OF OSTEOMYELITIS CAUSED BY SALMONELLA ENTERICA SUBSP. HOUTENAE IN A TAYLOR’S CANTIL (AGKISTRODON BILINEATUS TAYLORI) USING AMIKACIN DELIVERED VIA OSMOTIC PUMParticle Published on 2016-06-302024-09-01 Journal: Journal of Zoo and Wildlife Medicine [Category] 살모넬라증, [키워드] Agkistrodon Amikacin osmotic pump Osteomyelitis Salmonella snake [Article Type] article