The Interaction of Vasopressin with Hormones of the Hypothalamo–Pituitary–Adrenal Axis: The Significance for Therapeutic Strategies in Cardiovascular and Metabolic DiseasesReview Published on 2024-07-052024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] ACTH androgens AVP cardiac failure CRH Estrogens Glucocorticoids hypertension mineralocorticoids Stress [DOI] 10.3390/ijms25137394 PMC 바로가기 [Article Type] Review
Epidemiological profile of COVID-19 in patients with prostate cancer undergoing androgen deprivation therapy at a Brazilian Cancer CenterOriginal Article Published on 2023-10-102024-09-05 Journal: Einstein [Category] update2024, [키워드] androgens antineoplastic agents Coronavirus infections COVID-19 hormonal prostatic neoplasms SARS-CoV-2 [DOI] 10.31744/einstein_journal/2023AO0273 PMC 바로가기 [Article Type] Original Article
Use of Antiandrogens as Therapeutic Agents in COVID-19 PatientsReview Published on 2022-12-072023-07-11 Journal: Viruses [Category] COVID19(2023년), [키워드] ACE2 androgens antiandrogens coronavirus SARS-CoV-2 Sex hormones TMPRSS2 [DOI] 10.3390/v14122728 PMC 바로가기 [Article Type] Review
Characterization of Clinical Features of Hospitalized Patients Due to the SARS-CoV-2 Infection in the Absence of Comorbidities Regarding the Sex: An Epidemiological Study of the First Year of the Pandemic in BrazilArticle Published on 2022-07-222023-07-10 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), [키워드] androgens Brazil COVID-19 Epidemiology SARS-CoV-2 Sex. [DOI] 10.3390/ijerph19158895 PMC 바로가기
The Impact of Androgen Deprivation Therapy on COVID-19 Illness in Men With Prostate Cancer전립선암이 있는 남성의 COVID-19 질병에 대한 안드로겐 결핍 요법의 영향Multicenter Study Published on 2022-05-022022-09-11 Journal: JNCI Cancer Spectrum [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI 95% confidence interval addition adjusted Affect Analysis androgen Androgen receptor androgens body mass body mass index Cell clinical disease cohorts Comorbidity COVID-19 COVID-19 diagnosis COVID-19 disease COVID-19 illness death defined demonstrated Deprivation epithelial cells evaluated Follow-up hazard ratio higher risk Hospitalization illness Impact Logistic lower risk mechanical ventilation median median age multicenter multicenter study multivariable Not demonstrated Older outcomes overall survival oxygen Oxygenation Patient patients performed Prostate cancer protease Regression model regulated respiratory epithelial cells retrospective cohort SARS-CoV-2 SARS-CoV-2 viral severe COVID-19 severe COVID-19 disease severe COVID-19 illness significantly statistical test statistically suggested supplemental oxygen survival therapy TMPRSS2 Treatment upregulated within 6 months [DOI] 10.1093/jncics/pkac035 PMC 바로가기 [Article Type] Multicenter Study
Men with COVID-19 die. Women surviveShort communication Published on 2022-04-012022-10-05 Journal: Maturitas [Category] COVID19(2023년), SARS, 바이오마커, [키워드] 95%CI adjusted age androgens average COVID-19 determinant Estrogens Gender hormone Hospitalized Italy male men Menopause Mortality mortality rate outcome Patient Retrospective analysis risk factor SARS-CoV-2 severity Sex with COVID-19 women [DOI] 10.1016/j.maturitas.2021.11.014 [Article Type] Short communication
TELO-SCOPE study: a randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosisClinical Trial Published on 2021-12-012022-10-05 Journal: BMJ Open Respiratory Research [Category] 임상, [키워드] addition androgens approval base pairs children clinical conducted Diagnosis dose double-blind effective Efficacy Ethics ethics committee Evidence fibrosis Human intention to treat International interstitial Interstitial Fibrosis Mutation National New Nintedanib participant peer-reviewed peripheral blood cells phase 2 trial Placebo placebo-controlled Primary outcome pulmonary fibrosis randomised Randomised trial receive recent registry reported Result Side effect South Standard Standard of care subject telomere [DOI] 10.1136/bmjresp-2021-001127 PMC 바로가기 [Article Type] Clinical Trial
Are sex hormones promising candidates to explain sex disparities in the COVID-19 pandemic?Article Published on 2021-11-102023-06-16 Journal: Reviews in Endocrine & Metabolic Disorders [Category] MERS, [키워드] androgens COVID-19 Estrogens Progestins SERMs [DOI] 10.1007/s11154-021-09692-8 PMC 바로가기 [Article Type] Article
Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19Article Published on 2021-09-092022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] ACE2 acute respiratory syndrome ADAM17 analyzed androgen androgens angiotensin converting enzyme 2 cardiac cardiometabolic cathepsin L caused complications conditions coronavirus coronavirus disease COVID-19 Deleterious Dihydrotestosterone disorder Endocrine exacerbated expression fat Fat mass female furin high risk increase in kidney LFD mice mitigate Modification modulated mRNA expression obesity outcome Ovary Polycystic polycystic ovary Polycystic ovary syndrome positively correlated Protein protein expression receptor renal SARS-CoV-2 SARS-CoV-2 viral serum severity susceptibility syndrome TMPRSS2 TMPRSS4 treated Treatment upregulated weight loss women [DOI] 10.3390/ijms22189746 PMC 바로가기 [Article Type] Article
Association between SARS-CoV-2 infection and disease severity among prostate cancer patients on androgen deprivation therapy: a systematic review and meta-analysisInvited Review Published on 2021-09-032022-10-28 Journal: World Journal of Urology [Category] COVID-19, COVID19(2023년), SARS, [키워드] 95% CI absence ACE2 ADT Androgen deprivation therapy androgens angiotensin-converting enzyme 2 association Cancer therapy conducted confidence interval coronavirus disease COVID-19 COVID-19 pandemic COVID-19 severity database Deprivation disease severity enzyme Evidence exclusion criteria expression heterogeneity Inclusion Infection infection process infection risk involved Meta-analysis Patient patients patients treated Prostate Prostate cancer random regulated Result Retrospective study risk SARS-CoV-2 SARS-COV-2 infection selected severity systematic review the disease the SARS-CoV-2 therapy TMPRSS2 trajectory transmembrane serine protease undergo Web of Science worsening [DOI] 10.1007/s00345-021-03810-6 PMC 바로가기 [Article Type] Invited Review