SARS-CoV-2 and other coronaviruses negatively influence mitochondrial quality control: beneficial effects of melatonin
Article
[키워드] adenosine monophosphate-activated protein kinase, AMPK
Adenosine triphosphate, ATP
angiotensin converting enzyme 2, ACE2
Apoptosis
apoptosis inducing factor, AIF
apoptosis protease-activating factor 1, Apaf-1
arylalkylamine N-acetyltransferase, AANAT
autophagy
autophagy related genes, ATGs
caspase recruitment domains, CARDs
Chaperone proteins
Coronaviruses
coronaviruses, CoVs
COVID-19
deubiquitinating enzymes, DUBs
double-stranded RNA, dsRNA
fission
fusion
inner mitochondrial membranes, IMM
interferon regulatory factor 3, IRF3
interleukin, IL
long-OPA1, L-OPA1
mammalian target of rapamycin complex 1, mTORC1
melanoma differentiation-associated gene-5, MDA5
melatonin
middle-east respiratory syndrome coronavirus, MERS-CoV
mitochondrial associated antiviral signaling, MAVS
mitochondrial DNA, mtDNA
mitochondrial dynamics
mitochondrial permeability transition pore, mPTP
mitofusins, Mfn
murine hepatitis virus, MHV
NOD-like receptors protein 3, (NLRP3)
open reading frame, ORF
outer mitochondrial membrane, OMM
papain-like protease, PLpro
pathogen associated molecular patterns, PAMPs
presequenced translocase-associated motor, PAM
PTEN-induced putative kinase 1, PINK1
rabbit hemorrhagic disease virus, RHDV
reactive oxygen species, retinoic acid-inducible gene I, RIG-I, ROS
serotonin N-acetyltransferase, SNAT
severe acute respiratory syndrome coronavirus, SARS-CoV
short-OPA1, S-OPA1
translocase of the inner membrane, TIM
translocase of the outer membrane, TOM
transmissible gastroenteritis virus, TGEV
Ubiquitin-proteasome system, UPS
ULK1, (Unc-51-like kinase1)
[DOI] 10.1016/j.pharmthera.2021.107825 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.pharmthera.2021.107825 PMC 바로가기 [Article Type] Article