Role of Hydrogen Bonds in Formation of Co-amorphous Valsartan/Nicotinamide Compositions of High Solubility and Durability with Anti-hypertension and Anti-COVID-19 Potential항고혈압 및 항-COVID-19 잠재성을 지닌 높은 용해도 및 내구성을 갖는 공동-비정질 발사르탄/니코틴아미드 조성물의 형성에서 수소 결합의 역할Article Published on 2021-04-012022-08-31 Journal: Molecular Pharmaceutics [Category] 치료제, [키워드] (nicotinamide) acting active pharmaceutical ingredient analyses angiotensin Angiotensin II anti-hypertensive applied approaches Bioavailability bond caused characterized co-amorphization conformational change conformational changes coronavirus COVID-19 Density functional theory Donor drug drugs Effects Efficacy exhibit flexible Formation functional heterodimeric hydrogen Hydrogen bond hydrogen bonds hypertension ingredient Interaction key factor liquid low molecular weight lung market molecules NIC nicotinamide pandemic coronavirus Physicochemical properties Potential quantum theory receptor receptor blocker responsible role SARS-COV-2 infection solid dispersion solubility treat valsartan X-ray [DOI] 10.1021/acs.molpharmaceut.0c01096 PMC 바로가기 [Article Type] Article
Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers are not associated with increased risk of SARS-CoV-2 infectionArticle Published on 2020-08-202023-06-20 Journal: Journal of Travel Medicine [Category] Fulltext, MERS, [키워드] ACE2 receptor anti-hypertensive BMI body mass index COVID19 hypertension Israel obesity Vitamin D [DOI] 10.1093/jtm/taaa069 PMC 바로가기