Plasmodium falciparum Malaria Vaccines and Vaccine AdjuvantsReview Published on 2021-09-242024-09-02 Journal: Vaccines [Category] 대상포진, [키워드] Anti-malarial drugs Malaria vaccine Plasmodium falciparum Vaccine adjuvants [DOI] 10.3390/vaccines9101072 PMC 바로가기 [Article Type] Review
In vitro efficacy of artemisinin-based treatments against SARS-CoV-2Article Published on 2021-07-162022-10-04 Journal: Scientific Reports [Category] SARS, 신약개발, 치료제, [키워드] 50% effective concentration acute respiratory syndrome Anti-malarial drugs antiviral efficacy Antiviral treatment approved Artemisinin assays calculated Cancer caused Cell cells clinical Compound coronavirus coronavirus disease COVID-19 Drug discovery Efficacy evaluate experiment hepatoma Huh7.5 cell human lung immunostaining in vitro ingredient inhibited Patient peak plasma concentration required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike glycoprotein therapeutic window these compound Treatment utility VeroE6 cells viability viral infection [DOI] 10.1038/s41598-021-93361-y PMC 바로가기 [Article Type] Article
The journey of antimalarial drugs against SARS-CoV-2: Review articleReview article Published on 2021-05-192022-10-05 Journal: Informatics in Medicine Unlocked [Category] 신약개발, [키워드] acute respiratory syndrome affected Anti-malarial drugs antimalarial drug Antimalarial drugs Antiviral Chloroquine COIVD-19 combination therapy combinations coronavirus COVID-19 COVID-19 infection drug Drug repurposing Effect Efficacy exhibited faster global public health Hydroxychloroquine in vitro in vivo introduced investigated mechanism outbreak pandemic pandemic disease reducing repurposing review Safe SARS-CoV-2 Side effects Symptom tested the disease Treatment Trial [DOI] 10.1016/j.imu.2021.100604 [Article Type] Review article
Plasmodium infection and drug cure for malaria vaccine developmentarticle Published on 2021-02-282024-09-01 Journal: Expert review of vaccines [Category] 말라리아, [키워드] Anti-malarial drugs chemoprophylaxis vaccination (CVac) chemoprophylaxis with sporozoites (CPS) controlled human infection controlled Infection Immunization (CII) Immunity malaria Malaria vaccine [Article Type] article
Drug rechanneling: a novel paradigm for cancer treatmentArticle Published on 2020-12-022024-09-04 Journal: Seminars in cancer biology [Category] 대상포진, [키워드] Anti-diabetic drugs Anti-malarial drugs anti-psychotic drugs Anti-viral drugs Cancer repurposing [DOI] 10.1016/j.semcancer.2020.03.011 PMC 바로가기 [Article Type] Article
Efficacy and Safety of Anti-malarial Drugs (Chloroquine and Hydroxy-Chloroquine) in Treatment of COVID-19 Infection: A Systematic Review and Meta-AnalysisMedicine Published on 2020-07-292022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI Administered adverse event adverse events aminoquinoline anti-malarial drug Anti-malarial drugs arrhythmia Azithromycin cardiac event carried Chloroquine clinical trial Combination coronavirus COVID-19 COVID-19 infection database drug ECG Effect Efficacy eight evaluated Evidence Evidence-based medicine Good HCQ Hospitalized Hydroxychloroquine In-vitro increased risk Infection inhibit laboratory parameter Major material Meta-analysis Mortality no significant effect non-randomized trial observational studies OSF outcome outcome measure pandemic participant Participants patients Primary outcome provided QT prolongation RCT reached Registration required review risk Safety SARS-CoV-2 secondary significantly increased systematic review Treatment with COVID-19 [DOI] 10.3389/fmed.2020.00482 PMC 바로가기 [Article Type] Medicine
Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria전체 신체 생체 발광 이미징을 사용하여 실험적 쥐 말라리아 모델에서 전통적인 효능 테스트를 대체하는 수정된 톰슨 테스트 업데이트Methodology Published on 2019-02-152024-08-11 Journal: Malaria Journal [Category] 말라리아, [키워드] animal models Anti-malarial drugs bioluminescence In vivo imaging technology Parasitaemia readout Parasite load predicted parasitaemia (PLPP) Plasmodium berghei Preemptive euthanasia refinement [DOI] 10.1186/s12936-019-2661-x PMC 바로가기 [Article Type] Methodology
In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin새로운 하르민 유사체 열충격 단백질 90 억제제의 시험관 내 및 생체 내 항말라리아 활성이: 아르테미시닌의 가능한 파트너Research Published on 2016-12-012024-08-12 Journal: Malaria Journal [Category] 말라리아, [키워드] Anti-malarial drugs Heat-shock protein 90 malaria Plasmodium falciparum [DOI] 10.1186/s12936-016-1625-7 PMC 바로가기 [Article Type] Research
Psychiatric effects of malaria and anti-malarial drugs: historical and modern perspectives말라리아와 항말라리아 약물의 정신과적 효과: 역사적 및 현대적 관점Review Published on 2016-06-222024-08-12 Journal: Malaria Journal [Category] 말라리아, [키워드] Anti-malarial drugs malaria Malariotherapy Psychiatric effects Toxicity [DOI] 10.1186/s12936-016-1391-6 PMC 바로가기 [Article Type] Review
High efficacy of two artemisinin-based combinations: artesunate + sulfadoxine-pyrimethamine and artemether-lumefantrine for falciparum malaria in Yemen예멘에서의 팔수파룸 말라리아에 대한 두 가지 아르테미시닌 기반 조합의 높은 효능: 아르테수네이트 + 설파독신-피리메타민 및 아르테메터-루메파트린Research Published on 2015-11-142024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Anti-malarial drugs artemether-lumefantrine artesunate drug resistance Gametocytaemia Plasmodium falciparum sulfadoxine-pyrimethamine Yemen [DOI] 10.1186/s12936-015-0970-2 PMC 바로가기 [Article Type] Research