Coronavirus Disease 2019 Management Strategies in Solid Organ Transplant RecipientsArticle Published on 2023-03-212024-09-05 Journal: Infectious disease clinics of North America [Category] update2024, [키워드] anti-spike monoclonal antibodies coronavirus disease-2019 COVID-19 molnupiravir Nirmatrelvir Remdesivir transplantation [DOI] 10.1016/j.idc.2023.03.003 PMC 바로가기 [Article Type] Article
Outpatient anti-spike monoclonal antibody administration is associated with decreased morbidity and mortality among patients with cancer and COVID-19Research Published on 2023-02-132024-09-05 Journal: Clinical and experimental medicine [Category] update2024, [키워드] anti-spike monoclonal antibodies Cancer COVID-19 Infection SARS-CoV-2 [DOI] 10.1007/s10238-023-01019-y PMC 바로가기 [Article Type] Research
Variant of Concern-Matched COVID-19 Convalescent Plasma Usage in Seronegative Hospitalized Patients혈청 음성 입원 환자에서 우려 일치 COVID-19 회복기 혈장 사용의 변형Article Published on 2022-06-302022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] 28-day mortality advanced disease Adverse reaction Adverse reactions affecting age anti-spike monoclonal antibodies anti-spike monoclonal antibody Anti-viral therapy Blood donors CCP collected convalescent convalescent plasma COVID-19 COVID-19 convalescent plasma Delta Efficacy hospital Hospitalized hospitalized COVID-19 patient hospitalized patient Immunocompromised Immunocompromised patient Immunocompromised patients infused IQR Italian mAb mAbs median age mortality rate NAbs Neutralizing antibodies neutralizing antibody omicron outcome patients protective immune response Randomized controlled trial recipient reported rescued SARS-CoV-2 seronegative severe COVID-19 Support Two patient two patients Usage variants variants of concern VoC VOCs were recorded [DOI] 10.3390/v14071443 PMC 바로가기 [Article Type] Article
Effectiveness of Monoclonal Antibodies in Preventing Severe COVID-19 With Emergence of the Delta Variant델타 변이체의 출현으로 심각한 COVID-19를 예방하는 모노클로날 항체의 효과Article Published on 2022-02-012022-09-11 Journal: Mayo Clinic proceedings [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% CI adjusted Alpha Anti-spike anti-spike monoclonal antibodies anti-spike monoclonal antibody approved Beta Beta variant beta variants can not Charlson Comorbidity Index clinical setting Cohort Comorbidity COVID-19 death Delta delta variant effective strategy Effectiveness Efficacy emergence epoch excluded higher odd higher odds Hospitalization infused maintain monoclonal monoclonal antibodies monoclonal antibody Odds ratio outcome Patient predominant Preventing question retrospective cohort severe disease Severe infection the SARS-CoV-2 Treatment variant virulent [DOI] 10.1016/j.mayocp.2021.12.002 PMC 바로가기 [Article Type] Article
Spike Gene Evolution and Immune Escape Mutations in Patients with Mild or Moderate Forms of COVID-19 and Treated with Monoclonal Antibodies Therapies경증 또는 중등도 형태의 COVID-19 환자에서 스파이크 유전자 진화 및 면역 탈출 돌연변이 및 모노클로 날 항체 요법으로 치료Brief Report Published on 2022-01-242022-09-01 Journal: Viruses [Category] SARS, 변종, 진단, [키워드] administration anti-spike monoclonal antibodies anti-spike monoclonal antibody bamlanivimab clinical impact COVID-19 escape etesevimab Evolution form immune escape mutation Immunosuppressed immunosuppressed patients mAb mAbs Mild mixture moderate molecular molecular evolution monoclonal antibodies therapy Mutation outcomes Patient patients treated performed Q493R receiving SARS-CoV-2 spike spike gene two patients Virological [DOI] 10.3390/v14020226 PMC 바로가기 [Article Type] Brief Report
Successful Clearance of 300 Day SARS-CoV-2 Infection in a Subject with B-Cell Depletion Associated Prolonged (B-DEAP) COVID by REGEN-COV Anti-Spike Monoclonal Antibody Cocktailregen-cov 항-스파이크 모노클로 날 항체 칵테일에 의한 B- 세포 고갈 관련 장기 (B-DEAP) covid에서 300 일 SARS-COV-2 감염의 성공적인 허가Case Reports Published on 2021-06-232022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, [키워드] anti-CD20 anti-CD20-mediated B-cell depletion anti-COVID-19 vaccine anti-SARS-CoV-2 vaccination anti-spike monoclonal antibodies anti-spike monoclonal antibody B-cell B-cell depletion associated prolonged COVID-19 B-DEAP COVID-19 Care Chemotherapy clearance Clinical course clinical decision cocktail consolidation coordination COVID COVID-19 COVID-19 infection current Day Depletion develop Diagnosis disappearance dose failure FDA first dose follicular Follicular lymphoma Health Health care Hospitalized Humoral immunity immunology Infection infused infusion initial input IRB lymphoma male management Mild monoclonal antibodies monoclonal antibody mutations obinutuzumab Patient persistence Pfizer-BioNTech Pharmacology Prolonged quarantine REGEN-COV REGN10933 and REGN10987 required SARS-CoV-2 SARS-CoV-2 persistence SARS-CoV-2 virus spike mutation the patient therapeutic option therapy treated vaccination Virology virus clearance virus mutations was performed [DOI] 10.3390/v13071202 PMC 바로가기 [Article Type] Case Reports