Plant antibacterials: The challenges and opportunitiesReview Article Published on 2024-05-112024-09-05 Journal: Heliyon [Category] update2024, [키워드] antibacterials Gram-negative bacteria plants resistances [DOI] 10.1016/j.heliyon.2024.e31145 PMC 바로가기 [Article Type] Review Article
Interrogation of the contribution of (endo)lysin domains to tune their bacteriolytic efficiency provides a novel clue to design superior antibacterials(엔도)라이신 도메인이 박테리오리틱 효율을 조정하는 데 기여하는 것을 조사하는 것은 우수한 항균제를 설계하는 데 새로운 단서를 제공합니다.Article Published on 2022-12-312024-08-24 Journal: International Journal of Biological Macromolecules [Category] 폐렴구균 감염증, [키워드] (Endo)lysin antibacterials antimicrobial resistance bacteriophage Peptidoglycan hydrolase protein engineering Streptococcus pneumoniae
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease OutbreaksArticle Published on 2022-04-082022-10-04 Journal: ACS Infectious Diseases [Category] 신약개발, [키워드] activity antibacterials antifungals antivirals approach approved drug assays Box Care chemotype Community Compound domain drug Drug discovery emerging disease facilitate First wave Health Infectious disease information Medicine molecular target pandemic Pandemics pharmacological phenotypic repositioning response Screening second wave shown therapy Threats [DOI] 10.1021/acsinfecdis.1c00527 PMC 바로가기 [Article Type] Article
Surveillance of Antibacterial Usage during the COVID-19 Pandemic in England, 2020Article Published on 2021-07-102022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] Admission Analysis Antibacterial antibacterials Antibiotics anticipated Antimicrobial stewardship Bacterial caused change clinical feature Community conducted consequence COVID-19 COVID-19 pandemic Daily England evaluate the effect highlight hospital hospitals increases in Interrupted outcome pandemic Pandemics Patient primary care respiratory infection Respiratory tract infections SARS-CoV-2 secondary care severe respiratory infection syndrome Usage Volume was measured [DOI] 10.3390/antibiotics10070841 PMC 바로가기 [Article Type] Article
Discovery of macrozones, new antimicrobial thiosemicarbazone-based azithromycin conjugates: design, synthesis and in vitro biological evaluationarticle Published on 2020-11-302024-09-01 Journal: International Journal of Antimicrobial Agents [Category] 폐렴구균 감염증, [키워드] antibacterials Azithromycin in vitro evaluation Macrozones resistance thiosemicarbazones [Article Type] article
Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper #article Published on 2020-05-072024-09-02 Journal: Intensive care medicine [Category] 대상포진, [키워드] antibacterials antifungals antivirals Pharmacodynamics pharmacokinetics Sepsis [DOI] 10.1007/s00134-020-06050-1 PMC 바로가기 [Article Type] article
Synthesis of clarithromycin ketolides chemically modified at the unreactive C10-methyl groupC10-메틸 그룹에서 화학적으로 변형된 클라리트로마이신 케톨라이드의 합성Article Published on 2017-04-152024-08-24 Journal: Bioorganic & Medicinal Chemistry [Category] 폐렴구균 감염증, [키워드] Allylic substitutions antibacterials C10-aminomethyl-3-ketolides In vitro MIC data NCS acetoxylation stereoselectivity Syntheses.
Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold시아노티오펜 구조를 기반으로 한 두 번째 세대 MurF 억제제의 설계, 합성 및 평가journal-article Published on 2014-02-012024-08-04 Journal: European Journal of Medicinal Chemistry [Category] 폐렴구균 감염증, [키워드] antibacterials Enzyme inhibitors MurF peptidoglycan [DOI] 10.1016/j.ejmech.2013.11.031 [Article Type] journal-article