Maternal SARS-CoV-2 sero-surveillance using newborn dried blood spot (DBS) screening specimens highlights extent of low vaccine uptake in pregnant womenArticle Published on 2022-11-302022-11-15 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Adults analyzed Antibody concentrations Antibody neutralization Blood complications contributing to COVID COVID-19 delta variant dose Dried blood spots fetal General population help highlight Hospital admissions Immunity IMPROVE information Intervention Maternal MONITOR natural infection Newborn newborn screening omicron outcomes pregnant women proportion reduction in representing Result SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies serostatus specimen the SARS-CoV-2 the vaccine utility vaccination Vaccine women [DOI] 10.1080/21645515.2022.2089498 PMC 바로가기
COVID-19 vaccine-induced antibody and T-cell responses in immunosuppressed patients with inflammatory bowel disease after the third vaccine dose (VIP): a multicentre, prospective, case-control studyArticle Published on 2022-11-012022-11-15 Journal: The Lancet. Gastroenterology & Hepatology [Category] SARS, 진단, [키워드] adjusted age All participant anti-SARS-CoV-2 anti-TNF antibody Antibody binding antibody concentration Antibody concentrations approved available data boost booster case-control study combination therapy Concentration control group COVID-19 COVID-19 vaccine Diagnosis disease dose Evidence first dose geometric mean geometric mean ratio group groups had no healthy control healthy individuals heterologous vaccine homologous IBD Immunosuppressed immunosuppressed patient immunosuppressive Immunosuppressive treatment Infection Inflammatory bowel disease jak inhibitors multicentre multivariable nine no significant difference Older Older age participant Patient patients treated Pfizer Primary outcome receiving Receptor binding domain recipient recruited reduced regimen response S1 RBD SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 vaccination significantly significantly lower Support T-cell Response T-cell responses the healthy therapy Tofacitinib Treatment ulcerative colitis Vaccine vaccine dose vaccine doses vaccine-induced antibody response VIP were measured [DOI] 10.1016/S2468-1253(22)00274-6 PMC 바로가기
Comparison of the measured values of quantitative SARS-CoV-2 spike antibody assaysArticle Published on 2022-10-012022-11-15 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 진단, [키워드] Abbott Abbott SARS-CoV-2 IgG acute respiratory syndrome addition antibody antibody assay Antibody concentrations assays binding antibody unit coefficient comparable Concentration Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) Coronavirus-2 correlated correlation epidemiological purposes geometric indicated material Patient Pearson Quantitative Quantitative SARS-CoV-2 antibody assay ranged Roche SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 spike protein sera Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Siemen Siemens Spike protein The diagnostic sensitivity the SARS-CoV-2 the WHO was determined WHO [DOI] 10.1016/j.jcv.2022.105269 PMC 바로가기
Are higher antibody levels against seasonal human coronaviruses associated with a more robust humoral immune response after SARS-CoV-2 vaccination?Article Published on 2022-09-082022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] adjusted affected age anti-spike antibodies anti-spike antibody anti-Spike IgG anti-spike IgG antibodies Anti-spike IgG antibody antibodies antibody Antibody concentrations antigens appear association baseline Blood Canada coronavirus Correlation analysis COVID-19 COVID-19 infection COVID-19 testing demonstrated determine Endemic HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 human coronavirus human endemic coronaviruses humoral immune response IgG levels Immunity include increases in linear relationship Multiple regression multiple regression model not affect Observational cohort study participant Participants performed positive provided questionnaire data robust Sample SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 vaccines Scatter plot significant difference significantly higher tested vaccinated individual vaccination [DOI] 10.3389/fimmu.2022.954093 PMC 바로가기
Detecting Waning Serological Response with Commercial Immunoassays: 18-Month Longitudinal Follow-up of Anti-SARS-CoV-2 Nucleocapsid AntibodiesArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] Abbott Accuracy acute respiratory syndrome adjusted Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 immune response antibodies antibody Antibody concentrations Antibody detection Architect cohorts commercial immunoassay conducted convalescent individual coronavirus coronavirus disease COVID-19 cumulative dependent on Detection limit Elecsy ELISA enzyme-linked immunosorbent evaluated Follow-up Health care worker heterogenous highest IgG immune responses immunoassay immunoassays incidence individual Infection longitudinal lowest nucleocapsid protein Patient Reinfection response Roche SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 infections selected serological serological kinetics serum serum antibody Surveillance tested the SARS-CoV-2 threshold unique waning antibody. [DOI] 10.1128/spectrum.00986-22 PMC 바로가기
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval6~7주(표준 대비) 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 백신 투여 간격으로 더 높은 항체 반응이 생성됨Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] acute respiratory syndrome antibodies Antibody concentrations coronavirus coronavirus 2 COVID-19 Dosing dosing interval interval mRNA vaccine N terminal domain Prospective Study Receptor binding domain respiratory response SARS-CoV-2 serology spike Standard Vaccine [DOI] 10.1093/cid/ciab938 PMC 바로가기 [Article Type] Article
Measurements of SARS-CoV-2 antibody dissociation rate constant by chaotrope-free biolayer interferometry in serum of COVID-19 convalescent patients코로나19 회복기 환자의 혈청 내 무카오트로프 생물층 간섭계를 통한 SARS-CoV-2 항체 해리율 상수 측정Article Published on 2022-08-012022-09-12 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 진단, [키워드] Antibody concentrations avidity binding binding interaction binding kinetics Biolayer interferometry BLI children Clinical use clinical utility coated with convalescent COVID-19 patients COVID-19 COVID-19 convalescent patient COVID-19 convalescent patients COVID-19 patient Critical demonstrated dissociation dissociation rate Dissociation rate constant Efficiency functional intensity Kinetics knowledge Lower measurement non-specific pediatric probe RBD Real-time monitoring Receptor binding domain reduction reported SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 spike protein sera serum serum albumin serum antibody Vaccines were measured [DOI] 10.1016/j.bios.2022.114237 PMC 바로가기 [Article Type] Article
Use of Tumor Necrosis Factor-α Antagonists Is Associated With Attenuated IgG Antibody Response Against SARS-CoV-2 in Vaccinated Patients With Inflammatory Bowel Disease종양 괴사 인자-α 길항제의 사용은 염증성 장 질환이 있는 백신 접종 환자에서 SARS-CoV-2에 대한 약화된 IgG 항체 반응과 관련이 있습니다Observational Study Published on 2022-07-052022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] Against age antagonist antagonists anti-SARS-CoV-2 antibody anti-SARS-CoV-2 vaccination antibody Antibody concentrations Antibody titer Antibody titers Biologicals Blood blood sampling bowel Characteristics clinical Clinical characteristics Combination completion Concentration COVID-19 Crohn's disease defined demonstrated detectable disease Effect elapsed geometric geometric mean IBD IgG IgG antibodies IgG antibody IgG antibody titer IgG antibody titers immune response immunoassay immunomodulating Immunosuppressive medication immunosuppressive medications increased risk independent independent of Inflammatory Inflammatory bowel disease medication Microparticle monotherapy Most patients mRNA mRNA vaccines mRNA-based vaccine mRNA-based vaccines Multivariable models Patient patient age patients patients treated prospective observational cohort quantitative determination RBD receive receiving Receptor-binding domain regimen response S1 subunit sampling SARS-CoV-2 SARS-COV-2 infection Seroconversion serological response significantly lower Spike protein the receptor-binding domain the S1 subunit the spike protein titer TNF-α-antagonists treated Treatment Tumor ulcerative colitis vaccination Vaccine vector was used were measured were recorded [DOI] 10.3389/fimmu.2022.920333 PMC 바로가기 [Article Type] Observational Study
Anti-SARS-CoV-2 antibody response after 2 and 3 doses of BNT162b2 mRNA vaccine in patients with lymphoid malignancies림프성 악성종양 환자에서 BNT162b2 mRNA 백신 2회 및 3회 투여 후 항-SARS-CoV-2 항체 반응Article Published on 2022-06-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] affected anti-CD20 Anti-CD20 antibodies Anti-CD20 antibody anti-CD38 anti-RBD Anti-RBD IgG antibody antibody concentration Antibody concentrations Antibody Response B-cell malignancies B-cell malignancy benefit binding domain booster Cell Cohort Concentration conducted Course COVID-19 COVID-19 patient COVID-19 patients disorders dose effective evaluate haematological malignancies haematological malignancy Haematologicalmalignancies humoral Humoral response humoral responses IgG Immunocompromised increment IQR lymphoid lymphomas malignancies malignancy median monoclonal Mortality mRNA vaccination mRNA vaccine of BNT162b2 Patient patients patients treated plasma Plasma cell Prophylaxis quantification RBD SARS-CoV-2 Seroconversion seroconversion rate seroconverted serological serological response serology significantly spike the disease the vaccine therapy third dose Vaccine vaccine dose [DOI] 10.1016/j.cmi.2022.02.029 PMC 바로가기 [Article Type] Article
Changing Patterns of SARS-CoV-2 Seroprevalence among Canadian Blood Donors during the Vaccine Era백신 시대 동안 캐나다 헌혈자의 SARS-CoV-2 혈청 유병률 패턴 변화Article Published on 2022-04-272022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age anti-S antibody Antibody concentrations Asymptomatic benefit Blood blood donor Blood donors Canada capita Changing Concentration coronavirus country Donor donors estimate expand full length group groups Health Organizations Health policy Humoral immunity identify Interaction mathematical Mathematical models National natural infection nucleic acid nucleocapsid Older organization pandemic pattern peaked positive Predictive proportion public health remained respiratory roll SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2 spike second dose Seroprevalence severe acute respiratory syndrome Coronavirus Spike protein symptomatic infection These data vaccination Vaccine [DOI] 10.1128/spectrum.00339-22 PMC 바로가기 [Article Type] Article