Case Report: Hypergranular Platelets in Vaccine-Induced Thrombotic Thrombocytopenia After ChAdOx1 nCov-19 VaccinationCardiovascular Medicine Published on 2022-02-092022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] Admission antibody anticoagulation treatment approach ATP ChAdOx1 ChAdOx1 nCov-19 vaccination characterized contribute D-dimer female Granule healthy healthy control help hematological parameter highlight hospital investigated marker morphology observation parameter pathology Patient Peripheral blood peripheral blood smear Platelet Platelets Population presentation reduced remained returned SARS-CoV-2 vaccination study period TEM the patient therapeutic decision thrombocytopenia thrombosis thrombotic thrombotic risk transmission electron microscopy Treatment vaccination vaccine-induced thrombotic thrombocytopenia (VITT) venous was increased were assessed [DOI] 10.3389/fcvm.2022.824601 PMC 바로가기 [Article Type] Cardiovascular Medicine
Trends in Venous Thromboembolism Anticoagulation in Patients Hospitalized With COVID-19Research Published on 2021-06-112022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, SARS, [키워드] 95% CI adjusted hazard ratio adjusted odds ratio adults hospitalized age analyzed Anticoagulant anticoagulation anticoagulation treatment association Black patients cohort of patient cohort study complication of COVID-19 COVID-19 defined dissemination dose Evidence exposure finding Frequency hospital Hospitalization Hospitalized hospitals implementation Importance In-hospital in-hospital mortality logit lower mortality measure median Missed Mortality mortality rates multicenter objective participant Patient patients hospitalized patients with COVID-19 Point Probability Prophylactic prophylactic dose Prophylaxis ranged Relevance remained Result setting therapy Thromboembolism treated Treatment trend Variation Venous Thromboembolism VTE Weighting with COVID-19 women [DOI] 10.1001/jamanetworkopen.2021.11788 PMC 바로가기 [Article Type] Research
Staged acute mesenteric and peripheral ischemia treatment in COVID-19 patient: Case reportCase Report Published on 2021-06-092022-10-04 Journal: International Journal of Surgery Case Reports [Category] 치료법, [키워드] abdominal pain Acute limb ischemia Acute mesenteric ischemia anticoagulation treatment approach Atypical blood flow bowel Case report Coagulopathy COVID 19 COVID-19 COVID-19 disease diabete embolic events female gastrointestinal symptoms hemodynamic Hospitalized imaging include inefficient Infectious disease intestinal intestine invasive treatments Ischemia less life-threatening limb Local management Mechanical thrombectomy morbidity Mortality Necrosis necrotic organ system Patient peripheral ischemia presentation presenting reduce reduced reported Respiratory complications risk subsequent Support surgical surgical resection Treatment [DOI] 10.1016/j.ijscr.2021.106105 PMC 바로가기 [Article Type] Case Report
Hypoxia may be a determinative factor in COVID-19 progressionShort communication Published on 2021-05-092022-10-05 Journal: Current Research in Pharmacology and Drug Discovery [Category] 신약개발, [키워드] affected amantadine anticoagulation treatment country Course COVID-19 COVID-19 early treatment COVID-19 mortality COVID-19 pathogenesis COVID-19 patients COVID-19 progression Critical D-dimer develop disease downstream drug Effect effective events example fluvoxamine Hospitalization host-directed therapy Hypothesis hypoxia indicated initiated Leukocytosis low molecular weight Low molecular weight heparins Mortality N-acetylcysteine observation predictor Prophylaxis repurposing SARS-COV-2 infection SARS-CoV-2 post-exposure prophylaxis SARS-CoV-2 virus infection sleep apnea the disease Treatment [DOI] 10.1016/j.crphar.2021.100030 [Article Type] Short communication
Thromboembolic Complications in Covid-19: From Clinical Scenario to Laboratory EvidenceReview Published on 2021-04-272022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] anticoagulation treatment antithrombotic therapy Atherosclerosis Blood coagulation Cardiology cardiovascular complication cardiovascular complications clinical clinical risk factor Coagulation Complication COVID-19 COVID-19 infection described Disseminated intravascular coagulation European events highlight histological increased risk Infection Inflammatory involved laboratory parameter lesion mechanism moderate occur pandemic disease pathophysiological pathway Patient Prophylactic recruitment responsible risk Risk category risk stratification scenario Society thromboembolic thrombosis thrombotic Treatment Vascular Vascular endothelium [DOI] 10.3390/life11050395 PMC 바로가기 [Article Type] Review
Safety profile of enhanced thromboprophylaxis strategies for critically ill COVID-19 patients during the first wave of the pandemic: observational report from 28 European intensive care unitsObservational Study Published on 2021-04-222022-10-04 Journal: Critical Care [Category] MERS, 임상, [키워드] age Analysis anticoagulation anticoagulation treatment association bleeding body mass index clinical Clinical characteristics Clinical outcome Cohort Complication complications concern COVID COVID-19 COVID-19 patient COVID-19 patients Critical Critical illness Critically ill Critically ill patient defined demographics discharge Effect European event First wave Guidance heparin ICU ICUs increased risk Intensive care medicine intensive care unit Linear model log male Mortality multivariable occurred outcome outcomes pandemic Patient patients potential risk Prevalence Prophylaxis protocol raised receiving red blood cell reduced reduction in reported Result Safe Safety SARS-COV-2 infection standard care standard thromboprophylaxis supplementary material therapeutic anticoagulation Thromboembolic event Thromboembolic events Thromboprophylaxis thrombosis Trial was collected was used [DOI] 10.1186/s13054-021-03543-3 PMC 바로가기 [Article Type] Observational Study
Re-organization of the Vascular Surgery Department During the Acute Phase of the COVID19 Outbreak: Lessons Learned and Future PerspectivesObservational Study Published on 2021-04-012022-10-05 Journal: Annals of vascular surgery [Category] SARS, 임상, [키워드] acute phase acute respiratory syndrome Analysis anticoagulation treatment clinical manifestations Comorbidities Complication coronavirus COVID-19 outbreak COVID-19 patient COVID19 Department Diagnosis DVT expected Future Health health-care Hospital admission hospitalized patients increase in Infection information Intervention Italy Laboratory tests lesson Lombardia material medical record outbreak pandemic Pavia phase problem public health reduction in Regular reported resource retrospective SARS-CoV-2 Severe infection suffered surgery thrombosis [DOI] 10.1016/j.avsg.2020.12.001 PMC 바로가기 [Article Type] Observational Study
The relationship between cardiac injury, inflammation and coagulation in predicting COVID-19 outcomeCOVID-19 결과 예측에서 심장 손상, 염증 및 응고 사이의 관계Article Published on 2021-03-222022-09-01 Journal: Scientific Reports [Category] SARS, 바이오마커, 진단, [키워드] abnormality adverse outcome anticoagulation treatment association attenuate attenuation benefit change Coagulation Coagulopathy Complication confounders consecutive patient coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mortality CRP D-dimer determinant Effect Endpoint enrolled greater heparin Hospitalized In-hospital individuals Inflammation Inflammatory Inflammatory response Injury low molecular weight low molecular weight heparin mechanism Mortality observational study outcome PaO pathway Pneumonia Predictive markers primary endpoint Prognostic markers risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pneumonia sensitivity severity single-center subject therapy Treatment troponin T [DOI] 10.1038/s41598-021-85646-z PMC 바로가기 [Article Type] Article
Optimizing Management to Reduce the Mortality of COVID-19: Experience From a Designated Hospital for Severely and Critically Ill Patients in ChinaMedicine Published on 2021-03-102022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress analyzed anticoagulation anticoagulation treatment antiviral drug ARDS branch China Clinical features Comprehensive coronavirus disease correlation COVID-19 COVID-19 patient Critical Critically ill Critically ill patient CRRT cut-off value Cytokines effective ESR experience Fluid management glucocorticoid IL-6 IL-8 Ill Intervention intubated patients intubation Invasive mechanical ventilation laboratory data management moderate Mortality organ function PaO Patient patients procalcitonin reached reduce mortality reducing mortality renal replacement therapy retrospective Safe Serum ferritin severely and critically ill shown significantly higher single-center study Support survival syndrome therapy TNF-α Tongji Hospital Treatment treatment for COVID-19 treatment strategy Vaccine Valley ventilatory support [DOI] 10.3389/fmed.2021.582764 PMC 바로가기 [Article Type] Medicine
Coagulation dysfunction in ICU patients with coronavirus disease 2019 in Wuhan, China: a retrospective observational study of 75 fatal casesObservational Study Published on 2021-01-312022-10-04 Journal: Aging (Albany NY) [Category] MERS, SARS, 임상, [키워드] accompanied albumin Anticoagulant anticoagulant therapy Anticoagulant treatment anticoagulation treatment C-reactive protein cardiac injury Coagulation coagulation disorder coagulation dysfunction coronavirus disease Coronavirus disease 2019 COVID-19 Critically ill patient D-dimer death described diagnosed dysfunction Efficacy elevated fatal COVID-19 fibrinogen degradation products hypercoagulability ICU patient Inflammation Inflammatory Injury intensive care lactate dehydrogenase male median median age Patient patients treated retrospective survival Treatment widespread Wuhan Wuhan, China [DOI] 10.18632/aging.202223 PMC 바로가기 [Article Type] Observational Study