Bioinformatics pipeline unveils genetic variability to synthetic vaccine design for Indian SARS-CoV-2 genomes
Article
[키워드] aligned
amino acid change
antigenic
antigenic epitopes
B-cell epitope
bioinformatics
bioinformatics pipeline
can be used
clade
clades
conserved
conserved regions
criteria
epitope
Evolution
genetic variability
genomic
HLA allele
identify
immunogenic
MAFFT
MHC-I
MHC-II
Multiple sequence alignment
Mutation
Nextstrain
Non-synonymous
Non-Synonymous Signature SNP
performed
Phylogenetic analysis
primer
probe
Protein
Region
regions
reported
resulting
SARS-CoV-2
SARS-CoV-2 genome
SARS-CoV-2 pandemic
selected
SNP
SNPs
T-cell
T-cell epitope
T-cell epitopes
unique
Vaccine
Vaccine design
virus
virus detection
virus genome
[DOI] 10.1016/j.intimp.2022.109224 PMC 바로가기
[DOI] 10.1016/j.intimp.2022.109224 PMC 바로가기