Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodiesarticle Published on 2023-05-182024-09-05 Journal: Cell Reports [Category] update2024, [키워드] arenavirus cryo-EM Lassa fever Lassa mammarenavirus neutralizing antibody prefusion glycoprotein structure-based vaccine design [DOI] 10.1016/j.celrep.2023.112524 PMC 바로가기 [Article Type] article
Viral Zoonoses in Small Wild Mammals and Detection of Hantavirus, SpainArticle Published on 2022-06-012023-06-14 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] Apodemus sylvaticus arenavirus hantavirus Microtus arvalis Mus spretus poxvirus rodent-borne viruses serologic screening Spain vector-borne infections viruses zoonoses [DOI] 10.3201/eid2806.212508 PMC 바로가기
Characterization of RNA Sensing Pathways in Hepatoma Cell Lines and Primary Human HepatocytesArticle Published on 2021-11-042023-08-30 Journal: Cells [Category] E형 간염, [키워드] arenavirus coronavirus hepatoma cells Innate immunity interferon liver primary hepatocytes RIG-I RNA virus TLR3 [DOI] 10.3390/cells10113019 PMC 바로가기 [Article Type] Article
How Do Enveloped Viruses Exploit the Secretory Proprotein Convertases to Regulate Infectivity and Spread?Review Published on 2021-06-252022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] Activation Antiviral arenavirus binding block viral entry cleavage contributed convertase COVID-19 Dengue domain enveloped virus Fever function furin glycoprotein Hemorrhagic Host host cell implicated Infection Infectivity inhibition limit mechanism membrane membrane-bound Other pandemic Pandemics PC1 PC2 PCSK9 plasma membranes Proprotein proprotein convertases Proteins Regulation responsible S-protein SARS-CoV-2 secretory serine protease SKI-1/S1P Surface glycoprotein tested tissues to define Vaccine viral envelope viral infection viral infections viral surface virus viruses [DOI] 10.3390/v13071229 PMC 바로가기 [Article Type] Review
The Antiviral Effect of the Chemical Compounds Targeting DED/EDh Motifs of the Viral Proteins on Lymphocytic Choriomeningitis Virus and SARS-CoV-2Article Published on 2021-06-242022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] A549 antivirals arenavirus arenaviruses cell lines Cell toxicity cells Chemical Choriomeningitis Compound compounds Concentration coronavirus Coronaviruses DED/EDh motif drug target Effect exhibited exonuclease exonuclease (ExoN) motif include indicated inhibited LCMV Lymphocytic choriomeningitis Lymphocytic choriomeningitis virus (LCMV) MERS-CoV motif motifs nsp14 pathogenic viruses performed SARS-CoV SARS-CoV-2 SARS-COV-2 infection Simulation study targeting these compound treat Vero Viral protein Viral proteins virus was used [DOI] 10.3390/v13071220 PMC 바로가기 [Article Type] Article
Screening of Eurasian Tundra Reindeer for Viral Sequences by Next-Generation Sequencing차세대 시퀀싱에 의한 바이러스 서열에 대한 유라시아 툰드라 순록의 스크리닝Article Published on 2021-06-182022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 치료기술, [키워드] Rangifer tarandus animals Arctic arenavirus bovine circulating Climate change collected COVID-19 pandemic Culture detect diarrhea emerging viruses Fennoscandia flavivirus Health herpesvirus Human Iceland indicated Infectious disease Infectious diseases nasal NGS orthobunyavirus pandemic papillomavirus Part picornavirus potential transmission Prevalence receiving rectal swab reindeer roe deer Russia Screening sequence Sequencing analysis species these viruses Tundra Viral virus virus screening viruses wild animals [DOI] 10.3390/ijerph18126561 PMC 바로가기 [Article Type] Article
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathwaysResearch Article Published on 2021-06-072022-10-29 Journal: PLoS Pathogens [Category] COVID-19, [키워드] Acidic Alpha Anti-viral anti-viral activity approach arenavirus arenaviruses binding CD47 Cell cell surface receptors complexes dead cell Degradation demonstrated Ebola Ebola virus Endocytic pathway expressed greater HSV-1 human pathogen IL-4 In vitro infection Infection inhibit inhibited inhibitor Macrophage mice MLV Mutation New World pathogenic viruses pathway phagocytosis Protein pseudovirus required RNA virus SARS-CoV-2 SARS-CoV-2 pseudovirus SIRPA susceptible target cells Therapies Treatment vaccine strain variety vesicular stomatitis virus virus Zika Zika virus [DOI] 10.1371/journal.ppat.1009662 PMC 바로가기 [Article Type] Research Article
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of ArenavirusArticle Published on 2021-05-252023-08-29 Journal: Viruses [Category] E형 간염, [키워드] arenavirus LCMV RNA-dependent RNA polymerase STAT3 virus–host interactions [DOI] 10.3390/v13060976 PMC 바로가기 [Article Type] Article
Structural analysis of viral ExoN domains reveals polyphyletic hijacking eventsResearch Article Published on 2021-03-172022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] Analysis arenavirus cellular comparable conserved COVID-19 domain event exonuclease exonucleases genomes growth Host innate immune lack preserved Proofreading Protein RdRP reported reveal RNA virus RNA-dependent RNA polymerase sequence Signaling structural homology therapeutic strategy Viral proteins [DOI] 10.1371/journal.pone.0246981 PMC 바로가기 [Article Type] Research Article
Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host RecognitionArticle Published on 2021-02-102023-06-14 Journal: Journal of Virology [Category] Fulltext, 신종인플루엔자, [키워드] arenavirus Filovirus IFN response Influenza Innate immunity miRNA negative-strand RNA virus paramyxovirus viral replication [DOI] 10.1128/JVI.02274-20 PMC 바로가기