Helminth antigens differentially modulate the activation of CD4 + and CD8 + T lymphocytes of convalescent COVID-19 patients in vitro
기생충 항원은 시험관 내에서 회복기 COVID-19 환자의 CD4 + 및 CD8 + T 림프구의 활성화를 차등적으로 조절합니다
Article
[키워드] Activation
activation markers.
addition
African
age
analyzed
Antigen
antigens
Ascaris lumbricoides
Brugia malayi
caused
CD137
CD137 (4-1BB)
CD4
CD4+
CD4+ helper and CD8+ T cytotoxic T cells
CD69
CD8
CD8+
cell culture supernatants
cell-mediated immune response
convalescent COVID-19 patient
coronavirus
coronavirus disease
Coronavirus disease 2019
country
Course
COVID-19
COVID-19 patient
COVID-19 patients
cytokine expression
Cytotoxic T cell
Cytotoxic T cells
death
Disease progression
Effect
Endemic
evade
expression
Factors
flow cytometry
Frequency
genetics
helminth
Helminth antigens
helper
human immune response
Hypothesis
IFN-γ
IFNγ
IL-10
IL-6
immune
immune reactivity
immune responses
in vitro
incidence of COVID-19
investigated
mechanisms
moderate
modulate
MONITOR
Mortality
not affected
offer
Onchocerca volvulus
pandemic
parasites
PBMC
PBMCs
peptides
Prevalence
reactivity
reduced
reduction
remained
Respiratory disease
SARS-CoV-2
SARS-CoV-2 peptide
SARS-CoV-2 peptides
SARS-CoV-2 transmission
significantly
significantly increased
Spread
Stimulation
sub-Saharan Africa
Support
suppress
T cell
T cell response
T cells
T helper cells
T lymphocyte
TNFα
Vaccines
virus
was measured
were used
[DOI] 10.1186/s12916-022-02441-x PMC 바로가기 [Article Type] Article
[DOI] 10.1186/s12916-022-02441-x PMC 바로가기 [Article Type] Article