Safety and preliminary efficacy of sequential multiple ascending doses of solnatide to treat pulmonary permeability edema in patients with moderate to severe ARDS in a randomized, placebo-controlled, double-blind trial: preliminary evaluation of safety and feasibility in light of the COVID-19 pandemicRandomized Controlled Trial Published on 2022-04-042022-10-05 Journal: Trials [Category] COVID19(2023년), SARS, 임상, [키워드] activity Alter ARDS ARDS patient Ascending baseline causes Clinical characteristics clinical study clinical trial conducted COVID-19 COVID-19 ARDS patient COVID-19 pandemic COVID-19 patient doses double-blind DSMB edema Efficacy enrolled Enrollment Evidence exceptional feasibility groups indication interim analysis investigator less mandatory Multiple multiple ascending dose noradrenaline not differ observation period outcome Oxygenation pandemic parameter Patient patients with moderate permeability phase IIB placebo-controlled pulmonary Pulmonary edema pulmonary permeability Randomized required risk Safety Safety Monitoring Board SARS-CoV-2 Sepsis severe ARDS sick Solnatide Study design survival rate treat Trial Ventilation [DOI] 10.1186/s13063-022-06182-3 PMC 바로가기 [Article Type] Randomized Controlled Trial
Alpha coma EEG pattern in patients with severe COVID-19 related encephalopathyObservational Study Published on 2021-01-012022-10-05 Journal: Clinical neurophysiology : official journal of the [Category] 임상, [키워드] Alpha analysed Ascending Ascending reticular formation Brainstem Care Clinical management cognitive Coma comatose consecutive patient COVID-19 defined disease severity EEGs electroencephalogram Encephalitis Encephalopathy FIVE help hypoxia immune incidence indirect effects laboratory-confirmed management metabolic dysfunction neurological neurological manifestation neurological manifestations neurotropism Non-convulsive status not different pathophysiology Patient patients performed remained Respiratory failure SARS-CoV-2 SARS-CoV-2 neurotropism Sedation Seizures severe COVID-19 severity virus Withdrawal [DOI] 10.1016/j.clinph.2020.09.008 PMC 바로가기 [Article Type] Observational Study
Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic ThrombosisArticles Published on 2020-11-102022-10-28 Journal: The American Journal of Tropical Medicine and Hygi [Category] COVID-19, SARS, [키워드] Ascending beta coronavirus cause caused cough COVID-19 diagnose diagnosed with COVID-19 disease endothelial Fever hypoxia Infarction Infection Inflammatory mediators kidney manifestation other organs pandemic status physician Pneumonia readmission renal required SARS-CoV-2 Shortness of breath Thromboembolism thrombosis Thrombus tissue tropism virus worsened Wuhan, China [DOI] 10.4269/ajtmh.20-0869 PMC 바로가기 [Article Type] Articles
Ascending and Descending of Coronavirus Disease 2019 (COVID-19)Letter to Editor Published on 2020-04-102022-10-31 Journal: Galen Medical Journal [Category] COVID-19, [키워드] Ascending coronavirus COVID-19 Nidovirales Severe acute respiratory syndrome viruses [DOI] 10.31661/gmj.v9i0.1880 PMC 바로가기 [Article Type] Letter to Editor