Ascorbate – Communicable Diseases Research

Redox imbalance in COVID-19 pathophysiology

Article

Published on 2022-10-012022-11-16
Journal: Redox Biology [Category] 치료기술,

[키워드] alteration Analysis antioxidant Ascorbate association biochemical assay Blood circulating Clinical outcome contributing to control subject COVID COVID-19 COVID-19 infection Diagnosis electron Electron paramagnetic resonance enrichment analysis enrolled EPR evaluate greater ICAM-1 ICU indicated Inflammation Inflammatory intensive care marker Mortality mRNA Multiplex assay multivariate non-ICU non-specific Oxidant oxidative stress parameter pathophysiologic pathophysiology pathway performed Peripheral blood positive predict predicted quantified redox Redox imbalance reducing reduction in repetition required SARS-CoV-2 Sequencing serum Serum level significant increase subject subjects therapeutic strategy Topic transcriptomics TSLP uric acid Vascular VCAM-1 Virus Disease was performed
[DOI] 10.1016/j.redox.2022.102465 PMC 바로가기

On the origin of nitrosylated hemoglobin in COVID-19: Endothelial NO capture or redox conversion of nitrite?: Experimental results and a cautionary note on challenges in translational research

Short communication

Published on 2022-08-012022-10-05
Journal: Redox Biology [Category] 치료기술,

In vitro anti-influenza assessment of anionic compounds ascorbate, acetate and citrate

Article

Published on 2022-05-232023-06-24
Journal: Virology Journal [Category] 신종인플루엔자,

[키워드] Acetate Ascorbate citrate cytokine influenza A virus
[DOI] 10.1186/s12985-022-01823-0 PMC 바로가기

Vitamin C and COVID-19 treatment: A systematic review and meta-analysis of randomized controlled trials

비타민 C와 코로나19 치료: 무작위 대조 시험의 체계적인 검토 및 메타 분석

Meta-Analysis

Published on 2021-11-012022-09-11
Journal: Diabetes & metabolic syndrome [Category] 임상, 치료법,

Hypothesis of zinc ascorbate as best zinc ionophore for raising antiviral resistance against Covid-19

코로나19에 대한 항바이러스 저항성을 높이는 최고의 아연 이온통로로서 아스코르브산 아연의 가설

Article

Published on 2021-09-012022-09-11
Journal: Journal of medical virology [Category] SARS, 치료제,

[키워드] Antiviral Ascorbate clinical trial clinical trials Concentration drug in vitro Potential Prevent raising SARS‐CoV‐2 virus Test treat Treatment Vaccine Vitamin C Zinc zinc ascorbate
[DOI] 10.1002/jmv.26989 PMC 바로가기 [Article Type] Article

Ascorbate exacerbates iron toxicity on intestinal barrier function against Salmonella infection

Article

Published on 2020-12-312024-09-06
Journal: J Environ Sci Health C Toxicol Carcinog [Category] 살모넬라증,

[키워드] Ascorbate Infection iron supplementation pro-oxidation Toxicity
PMC 바로가기

What Can Cellular Redox, Iron, and Reactive Oxygen Species Suggest About the Mechanisms and Potential Therapy of COVID-19?

Cellular and Infection Microbiology

Published on 2020-12-142022-10-31
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory distress Alter ARDS Ascorbate Can cause cellular chelators coronavirus disease COVID-19 Critical Diseases disrupt Effects Evidence Ferroptosis generate glutathione help Infection iron oxidative damage Perspective Potential producing Protein provide reactive oxygen specy redox Redox imbalance Repair mechanisms resource ROS ROS—reactive oxygen species Signaling Specific Specy Stress syndrome therapeutic intervention treat
[DOI] 10.3389/fcimb.2020.569709 PMC 바로가기 [Article Type] Cellular and Infection Microbiology

Vitamin C—An Adjunctive Therapy for Respiratory Infection, Sepsis and COVID-19

Review

Published on 2020-12-072022-10-30
Journal: Nutrients [Category] COVID-19, MERS, SARS,

The Emerging Role of Vitamin C in the Prevention and Treatment of COVID-19

Editorial

Published on 2020-10-272022-10-31
Journal: Nutrients [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory distress syndrome administration affecting Anti-inflammatory antioxidant Antithrombotic appear Ascorbate ascorbic acid carried China country COVID-19 Critically ill patient decrease decreased mortality deficiency Efficacy effort elevated Evidence functions greater group IMPROVE include indicated Intervention intravenous investigation low-middle-income monotherapy Mortality observational study optimization overlap oxidative stress Patient patients with COVID-19 patients with pneumonia physiological functions plasma pleiotropic Pneumonia Population prevention protocol Randomized controlled trial Randomized controlled trials RCT RCTs reduce Registered Research risk factor Risk factors role safety profile Sepsis severe coronavirus disease severe respiratory infections severely ill patient severity significantly sustained the disease translation Treatment Trial trials Vitamin Vitamin C with COVID-19
[DOI] 10.3390/nu12113286 PMC 바로가기 [Article Type] Editorial

De novo design, retrosynthetic analysis and combinatorial synthesis of a hybrid antiviral (VTAR-01) to inhibit the interaction of SARS-CoV2 spike glycoprotein with human angiotensin-converting enzyme 2

Research Article

Published on 2020-10-152022-10-27
Journal: Biology open [Category] COVID-19,

[키워드] De novo designing ACE2 Analysis angiotensin converting enzyme 2 Antiviral antiviral molecule Ascorbate bind binding caused complex COVID-19 disease de novo dependent on docking domain enzyme hACE2 high mortality human Angiotensin-converting enzyme Hybrid antiviral molecule Hydroxychloroquine Infection inhibit interact Interaction MDs molecular Molecular dynamics simulation morbidity outbreak Pathogenesis Protein RBD RBD-ACE2 recognize responsible Retrosynthetic analysis ribavirin SARS-CoV2 SARS-CoV2 spike glycoprotein SARS-like coronavirus spike spike glycoprotein Spike protein tested the receptor-binding domain variant virus were used
[DOI] 10.1242/bio.054056 PMC 바로가기 [Article Type] Research Article