Advancement in the Antigenic Epitopes and Vaccine Adjuvants of African Swine Fever VirusReview Published on 2024-08-212024-09-05 Journal: Pathogens [Category] update2024, [키워드] African Swine Fever Virus antigenic epitope B-cell epitope T-cell epitope Vaccine adjuvants [DOI] 10.3390/pathogens13080706 PMC 바로가기 [Article Type] Review
Enhanced Assessment of Cross-Reactive Antigenic Determinants within the Spike ProteinArticle Published on 2024-07-262024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] antibody-mediated enhancement B-cell epitope COVID-19 dengue virus SARS-CoV-2 variants Spike protein vaccination [DOI] 10.3390/ijms25158180 PMC 바로가기 [Article Type] Article
Identification of conserved cross-species B-cell linear epitopes in human malaria: a subtractive proteomics and immuno-informatics approach targeting merozoite stage proteinsarticle Published on 2024-02-282024-09-01 Journal: Frontiers in immunology [Category] 말라리아, [키워드] B-cell epitope conserved cross-species immunoinformatics P. falciparum Subtractive proteomics [Article Type] article
Antigen epitopes of animal coronaviruses: a mini-reviewarticle Published on 2023-05-172024-09-05 Journal: Animal Diseases [Category] update2024, [키워드] animal coronavirus antigen epitope B-cell epitope immune responses T-cell epitope Vaccines [DOI] 10.1186/s44149-023-00080-0 PMC 바로가기 [Article Type] article
Identification of a novel linear B-cell epitope in porcine deltacoronavirus nucleocapsid proteinarticle Published on 2023-01-052024-09-05 Journal: Applied Microbiology and Biotechnology [Category] update2024, [키워드] B-cell epitope monoclonal antibodies N protein PDCoV [DOI] 10.1007/s00253-022-12348-5 PMC 바로가기 [Article Type] article
Modular nanoarray vaccine for SARS-CoV-2Article Published on 2022-11-012022-11-15 Journal: Nanomedicine : nanotechnology, biology, and medici [Category] SARS, 변종, 진단, [키워드] B-cell epitope children complementary COVID-19 pandemic defined delta variant DNA effective epitope generate Gold nanoparticle IgG immune response immunized immunocompromised individuals immunogen immunogenic inactive mice mRNA neutralizing antibody PADRE peptide pregnant women probe recombinant proteins resulting SARS-CoV-2 spike glycoprotein time-consuming Vaccine Vaccine development vaccine platform Variants of concerns (VOC). virus neutralizing titer virus-like particles viruses VoC while wildtype [DOI] 10.1016/j.nano.2022.102604 PMC 바로가기
Bioinformatics pipeline unveils genetic variability to synthetic vaccine design for Indian SARS-CoV-2 genomesArticle Published on 2022-11-012022-11-15 Journal: International immunopharmacology [Category] SARS, 치료기술, 치료제, [키워드] aligned amino acid change antigenic antigenic epitopes B-cell epitope bioinformatics bioinformatics pipeline can be used clade clades conserved conserved regions criteria epitope Evolution genetic variability genomic HLA allele identify immunogenic MAFFT MHC-I MHC-II Multiple sequence alignment Mutation Nextstrain Non-synonymous Non-Synonymous Signature SNP performed Phylogenetic analysis primer probe Protein Region regions reported resulting SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 pandemic selected SNP SNPs T-cell T-cell epitope T-cell epitopes unique Vaccine Vaccine design virus virus detection virus genome [DOI] 10.1016/j.intimp.2022.109224 PMC 바로가기
A newly discovered PD-L1 B-cell epitope peptide vaccine (PDL1-Vaxx) exhibits potent immune responses and effective anti-tumor immunity in multiple syngeneic mice models and (synergizes) in combination with a dual HER-2 B-cell vaccine (B-Vaxx)새로 발견된 PD-L1 B세포 에피토프 펩타이드 백신(PDL1-Vaxx)은 여러 동종 유전자 마우스 모델에서 강력한 면역 반응과 효과적인 항종양 면역을 나타내며, 이중 HER-2 B세포 백신(B-Vaxx)과 병용 시 시너지 효과를 발휘합니다.Article Published on 2022-10-052024-08-19 Journal: Oncoimmunology [Category] 파상풍, [키워드] B-cell epitope CT26 D2F2/E2 Immunotherapy PD-L1 Peptide-vaccine
Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine범사르베코바이러스 수지상세포 표적화 백신의 설계, 면역원성 및 효능Article Published on 2022-06-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] Antigen antigens antiviral efficacy B-cell epitope B-cell epitopes BNT162b2 CD40 conserved Coronaviruses COVID-19 cross-neutralizing antibodies cross-neutralizing antibody cross-reactive demonstrated dendritic cells Efficacy elicited ENhance Epitopes framework functional hACE2 homologous immunization immunogenic immunogenicity in vitro initiative K18-hACE2 transgenic mice Medicine MERS mice mRNA BNT162b2 vaccine Mutation Neutralizing antibodies nucleocapsid potency Pre-clinical model protein subunit vaccine recall Sarbecoviruses SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 S spike Subunit vaccine supported surface receptor survival T-cell Response T-cell responses Vaccine variants of concern Viral viral control VoC VOCs [DOI] 10.1016/j.ebiom.2022.104062 PMC 바로가기 [Article Type] Article
Design of a Recombinant Multivalent Epitope Vaccine Based on SARS-CoV-2 and Its Variants in Immunoinformatics Approaches면역정보학 접근법에서 SARS-CoV-2 및 그 변이체에 기반한 재조합 다가 에피토프 백신의 설계Article Published on 2022-05-062022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, [키워드] allergen antigen epitope antigen epitopes approach B-cell epitope caused cellular conformational Coverage COVID-19 cytotoxic T lymphocyte docking effective Epidemic epitope Epitopes global public health Humoral immunity Immune simulation immunoinformatics IMPROVE in vitro in vivo Interaction linear B-cell epitope linear B-cell epitopes linker lymphocyte multivalent multivalent vaccine mutated virus Protein recombinant SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants screened strain strong interaction T lymphocyte the vaccine tlr-3 Vaccine variant variants VoC [DOI] 10.3389/fimmu.2022.884433 PMC 바로가기 [Article Type] Article