Dual-sgRNA CRISPRa System for Enhanced MK-7 Production and Salmonella Infection Mitigation in Bacillus subtilis natto Applied to Caco-2 Cells이중 sgRNA CRISPRa 시스템을 이용한 Bacillus subtilis natto의 MK-7 생산 증대 및 Salmonella 감염 완화, Caco-2 세포에 적용Article Published on 2024-02-282024-08-21 Journal: Journal of Agricultural and Food Chemistry [Category] 살모넬라증, [키워드] Bacillus subtilis dual-sgRNA CRISPRa system menaquinone-7 precise regulation. Salmonella
Recurrent Bacillus subtilis Var. Natto Bacteremia and Review of the Literature on Bacillus subtilis : The First Case ReportArticle Published on 2024-02-092024-09-05 Journal: The American journal of case reports [Category] update2024, [키워드] Bacillus subtilis Bacteremia Gastrointestinal diseases Probiotics [DOI] 10.12659/AJCR.942553 PMC 바로가기 [Article Type] Article
A rare case of Bacillus subtilis variant natto -induced persistent bacteremia with liver and splenic abscesses in an immunocompetent patientCase Report Published on 2024-01-142024-09-05 Journal: IDCases [Category] update2024, [키워드] Bacillus subtilis Bacillus subtilis variant natto immunocompetent Persistent bacteremia [DOI] 10.1016/j.idcr.2024.e01925 PMC 바로가기 [Article Type] Case Report
Bacillus subtilis spores displaying RBD domain of SARS-CoV-2 spike proteinResearch Article Published on 2023-02-082024-09-05 Journal: Computational and Structural Biotechnology Journal [Category] update2024, [키워드] Bacillus subtilis CotY CotZ RBD Spore surface display [DOI] 10.1016/j.csbj.2023.02.007 PMC 바로가기 [Article Type] Research Article
Oral administration of recombinant Bacillus subtilis expressing a multi-epitope protein induces strong immune responses against Salmonella Enteritidisarticle Published on 2023-01-312024-09-01 Journal: Veterinary Microbiology [Category] 살모넬라증, [키워드] Bacillus subtilis Salmonella Enteritidis Vaccine [Article Type] article
Towards Covid-19 TMPRSS2 enzyme inhibitors and antimicrobial agents: Synthesis, antimicrobial potency, molecular docking, and drug-likeness prediction of thiadiazole-triazole hybridsResearch article Published on 2022-11-012022-10-05 Journal: Journal of Molecular Structure [Category] 치료제, [키워드] 1 2 3 3-Triazoles 4-Thiadiazole analogue antimicrobial activity Bacillus subtilis binding affinity Candida albican candidate chalcone chloride Compound COVID-19 drug-likeness enzyme Escherichia coli exhibited FIVE Hydrazonoyl halides identify in silico in vitro inhibitor molecular docking pathogen Prevent proliferation Pseudomonas aeruginosa screened Staphylococcus aureus submitted synthesis synthesised therapeutic activity TMPRSS2 TMPRSS2 enzyme transmembrane serine protease Treatment Vanillin was tested [DOI] 10.1016/j.molstruc.2022.133659 [Article Type] Research article
Bacillus subtilis programs the differentiation of intestinal secretory lineages to inhibit Salmonella infection바실러스 서브틸리스는 장 분비 계통의 분화를 조절하여 살모넬라 감염을 억제한다.Article Published on 2022-09-272024-08-22 Journal: Cell Reports [Category] 살모넬라증, [키워드] Bacillus subtilis CP: Microbiology differentiation intestinal epithelium. Notch pathway Salmonella Typhimurium
A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myelomaCase report Published on 2022-08-012022-10-05 Journal: Journal of infection and chemotherapy : official j [Category] 변종, 치료법, [키워드] acute respiratory syndrome Admission age association B. subtilis Bacillus subtilis Bacteremia Bacteria Bacterial Blood caused conditions coronavirus coronavirus disease COVID-19 Critical Culture cultures Diabetes Mellitus Diabetic diagnosed during treatment End-stage renal disease Hemodialysis hospital Immunocompromised immunosuppressive ingestion intestinal inflammation intestinal permeability malignant tumor Multiple myeloma nephropathy next-generation sequencer Patient risk steroid symptomatic the patient therapy Tocilizumab translocation treated Treatment vancomycin VAR [DOI] 10.1016/j.jiac.2022.05.006 [Article Type] Case report
Methyl β-D-galactopyranoside esters as potential inhibitors for SARS-CoV-2 protease enzyme: synthesis, antimicrobial, PASS, molecular docking, molecular dynamics simulations and quantum computationsSARS-CoV-2 프로테아제 효소에 대한 잠재적 억제제로서의 메틸 β-D-갈락토피라노사이드 에스테르: 합성, 항균, PASS, 분자 도킹, 분자 역학 시뮬레이션 및 양자 계산Article Published on 2022-04-012022-09-11 Journal: Glycoconjugate journal [Category] Coronavirus, COVID19(2023년), SARS, 치료제, [키워드] activate active site activities aliphatic antimicrobial aromatic ASN142 AutoDock AutoDock vina Bacillus subtilis Bacteria binding affinities binding modes can be used chemical structures Combination Compound computation Concentration Cys145 demonstrated Density functional theory determine distribution docking drug-likeness drugs Efficacy electrostatic enthalpy Escherichia coli evaluated FIVE free energy fungal pathogens fungi Gly143 group His41 hydrogen Hydrogen bond in silico in vitro inhibitor inhibitory concentration Interaction kinetic MBC metabolism Methyl β-D-galactopyranoside MGP molecular molecular docking molecular dynamics Molecular dynamics simulation Pass Pathogens performed pharmacokinetic physicochemical protease residues SAR SARS-CoV-2 main protease SARS-CoV-2 protease SARS-CoV-2 protease. selected statistical analysis Strains Structure structure activity relationship sugar synthesis the binding affinity the SARS-CoV-2 theory THR26 Toxicity treated variety [DOI] 10.1007/s10719-021-10039-3 PMC 바로가기 [Article Type] Article
Probiotic Bacillus subtilis LF11 Protects Intestinal Epithelium Against Salmonella Infection프로바이오틱 바실러스 서브틸리스 LF11이 장 상피를 살모넬라 감염으로부터 보호합니다.Original Research Published on 2022-02-162024-07-29 Journal: Frontiers in Cellular and Infection Microbiology [Category] 살모넬라증, [키워드] Bacillus subtilis exclusion activity Inflammatory cytokines Intestinal barrier Salmonella infection tight junction [DOI] 10.3389/fcimb.2022.837886 PMC 바로가기 [Article Type] Original Research