Comparative Analysis of the Clarus Aspergillus Galactomannan Enzyme Immunoassay Prototype for the Diagnosis of Invasive Pulmonary Aspergillosis in Bronchoalveolar Lavage FluidOriginal Article Published on 2024-07-182024-09-05 Journal: Mycopathologia [Category] update2024, [키워드] BALF diagnostics Enzyme-linked immunoassay galactomannan Invasive pulmonary aspergillosis [DOI] 10.1007/s11046-024-00876-9 PMC 바로가기 [Article Type] Original Article
Extracellular Vesicles in Lung Cancer: Implementation in Diagnosis and Therapeutic PerspectivesReview Published on 2024-05-222024-09-05 Journal: Cancers [Category] update2024, [키워드] BALF EVs liquid biopsy lung cancer NSCLC Organ failure Personalized medicine SCLC [DOI] 10.3390/cancers16111967 PMC 바로가기 [Article Type] Review
Comparative study of diagnostic efficacy of sputum and bronchoalveolar lavage fluid specimens in community-acquired pneumonia children treated with fiberoptic bronchoscopyarticle Published on 2023-08-292024-09-05 Journal: BMC Infectious Diseases [Category] update2024, [키워드] BALF CAP pediatric sputum [DOI] 10.1186/s12879-023-08522-3 PMC 바로가기 [Article Type] article
Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathwayArticle Published on 2023-01-302022-11-16 Journal: Journal of ethnopharmacology [Category] 신종인플루엔자, 치료기술, [키워드] acute lung injury analyzed Anti-inflammation Apoptosis approved attenuate BALF Bcl-xL caspase Cell changes China confocal microscope coronavirus COVID-19 declined downstream drug Effect expression fatal complication flow cytometry food Granule H1N1 influenza histological histopathological IL-1β IL-6 immunofluorescence Infectious disease Influenza virus inhibited injection intrinsic investigated Jinhua Qinggan granules LPS lung Lung injury Lungs material mechanism mice Mild mitochondrial apoptotic pathway moderate morbidity and mortality MPO neutrophil Neutrophil apoptosis novel coronavirus disease Nuclear factor kappa-B nuclei p65 pathway pharmacological positive proportion Protein protein concentration protein expression pulmonary inflammation receptor reduced Respiratory disease Respiratory virus infection Signaling signaling pathway significantly staining survival survival rate TLR4 TNF-α toll-like receptor 4 treated Treatment were assessed were measured [DOI] 10.1016/j.jep.2022.115763 PMC 바로가기
Low BALF CD4 T cells count is associated with extubation failure and mortality in critically ill covid-19 pneumonia낮은 BALF CD4 T 세포 수는 중환자의 covid-19 폐렴에서 발관 실패 및 사망률과 관련이 있습니다Article Published on 2022-12-012022-09-11 Journal: Annals of Medicine [Category] 바이오마커, 진단, [키워드] affected alveolar alveolar macrophage analysed average BALF BALF CD4 T-cells count baseline Biomarker bivariate analysis Bronchoalveolar lavage fluid caspase caspase-3 cause CD4 CD4 T cell CD4 T-cell Characteristics clinical Clinical characteristics conducted COVID-19 COVID-19 patients COVID-19 pneumonia COVID-19 pneumonia patient COVID-19 pneumonia patients Critically ill critically ill COVID-19 patients Critically ill COVID-19 pneumonia D-dimer D-dimer level eight enrolled extubation failure. groups help IL-17 IL-6 immunopathology IMPROVE Indonesia intubation Invasive mechanical ventilation Laboratory lung Macrophage material Mortality no significant difference no significant differences outcome Patient performed Pneumonia profile Referral reported right lung severe pneumonia severity significant differences significantly survived T-cells Tertiary Tregs understanding was performed were measured [DOI] 10.1080/07853890.2022.2095012 PMC 바로가기 [Article Type] Article
Atypical pneumonia caused by Chlamydia psittaci during the COVID-19 pandemicResearch article Published on 2022-09-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 진단, 치료기술, [키워드] 48 hours Atypical Atypical pneumonia BALF Blood Bronchoalveolar lavage fluid causative pathogen caused China Chlamydia Chlamydia psittaci clinical clinically conducted COVID-19 COVID-19 infection COVID-19 pandemic described diagnosed Diagnosis ELISA enrolled Genome highest information mNGS nasal swab Next-generation sequencing objective outcomes pathogen Patient patients PCR Peripheral blood Pneumonia Psittacosis Result Retrospective study sequence sputum sputum samples Symptom Treatment treatment regimen was collected was performed [DOI] 10.1016/j.ijid.2022.07.027 [Article Type] Research article
NMR spectroscopy spotlighting immunogenicity induced by COVID-19 vaccination to mitigate future health concernsReview article Published on 2022-08-222022-10-05 Journal: Current Research in Immunology [Category] 바이오마커, 유전자 메커니즘, [키워드] affected Analysis approach BALF biological samples Biomarker Blood breast milk Bronchoalveolar-lavage fluid cerebrospinal fluid chemometrics complex COVID-19 COVID-19 vaccination CSF described detect disease examined example explain Health immunogenicity IMPROVE management metabolome mitigate molecular NMR NMR spectroscopy nuclear Nuclear magnetic resonance spectroscopy PCA Saliva Semen statistical the disease Treatment Urine vaccination Vaccine [DOI] 10.1016/j.crimmu.2022.08.006 [Article Type] Review article
SARS-CoV-2-positive patients display considerable differences in proteome diversity in urine, nasopharyngeal, gargle solution and bronchoalveolar lavage fluid samplesSARS-CoV-2-양성 환자는 소변, 비인두, 양치액 및 기관지폐포 세척액 샘플에서 단백질체 다양성에 상당한 차이를 나타냅니다.Article Published on 2022-08-082022-09-11 Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 BALF Beijing Bronchoalveolar lavage fluid center chance change characterized Charle China collected coronavirus coronavirus 2 database demonstrated Department downloaded followed by gargle gargle solution Germany Human human body in urine individual infected with SARS-CoV-2 Infection information investigated Mayo Clinic Medicine nasopharyngeal nasopharyngeal sample Nasopharyngeal samples pathology peptide Protein Proteins proteome proteomic proteomics respiratory SARS-CoV-2 SARS-CoV-2 pathogenesis SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 proteome SARS-CoV-2 virus SARS-CoV-2 viruses SARS-CoV-2-positive patient SARS-CoV-2-positive patients Science secreted seropositive individuals Severe acute respiratory syndrome significantly more solution status technology the SARS-CoV-2 virus UniProt unique university Urine USA virus viruses was used while [DOI] 10.1371/journal.pone.0271870 PMC 바로가기 [Article Type] Article
Metagenomic Next-Generation Sequencing Reveals the Profile of Viral Infections in Kidney Transplant Recipients During the COVID-19 PandemicMetagenomic 차세대 시퀀싱은 COVID-19 팬데믹 기간 동안 신장 이식 수혜자의 바이러스 감염 프로필을 보여줍니다Article Published on 2022-07-112022-09-11 Journal: Frontiers in Public Health [Category] 치료기술, [키워드] Analysis BALF Biomarker Blood Blood samples Bronchoalveolar lavage fluid CMV compared and analyzed COVID-19 COVID-19 pandemic cytomegalovirus database detection rate dominant higher risk IMPROVE indicated Infection JC polyomavirus kidney kidney transplant recipient kidney transplant recipients Kidney transplantation metagenomic Metagenomic next-generation sequencing Next-generation sequencing nucleic acid nucleic acids profile recipient rejection reveal sequence simian virus torque teno virus Transplant Urine viral infection viral infections viral nucleic acid viral nucleic acids virus virus infection viruses [DOI] 10.3389/fpubh.2022.888064 PMC 바로가기 [Article Type] Article
Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum폴리(I:C) 플러스 명반과 관련된 SARS-CoV-2 삼량체 스파이크 단백질의 면역원성Article Published on 2022-06-302022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] addition adjuvant adjuvants alum antibody B cell BALF Bronchoalveolar lavage fluid CD4 CD8 Cellular immune response Combination domain ELISA enzyme evaluated expected germinal centers IgA IgG IgG anti-spike antibody IgG1 IgG2a immunization immunogenicity immunosorbent in vitro inactivated induce intradermal route lung Lung inflammation mice Neutralization assay Neutralizing titer neutralizing titers neutrophil recruitment New Poly (I:C) poly(I:C positive prefusion produced producing Protein RBD reduced reduction in required SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 virus serum spike Spike protein Subtypes supported T cell Th1 Th1 phenotype the SARS-CoV-2 trimeric vaccination Vaccination strategy Vaccine [DOI] 10.3389/fimmu.2022.884760 PMC 바로가기 [Article Type] Article