Virological characteristics of a SARS-CoV-2-related bat coronavirus, BANAL-20-236Article Published on 2024-06-042024-09-05 Journal: eBioMedicine [Category] update2024, [키워드] BANAL-20-236 bat coronavirus SARS-CoV-2 spillover [DOI] 10.1016/j.ebiom.2024.105181 PMC 바로가기 [Article Type] Article
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19Article Published on 2023-03-062024-09-05 Journal: EMBO Reports [Category] update2024, [키워드] adaptive mutations animal model bat coronavirus Microbiology, Virology & Host Pathogen Interaction Pathogenesis serology [DOI] 10.15252/embr.202256055 PMC 바로가기 [Article Type] Article
Insertion/deletion hotspots in the Nsp2, Nsp3, S1, and ORF8 genes of SARS-related coronavirusesArticle Published on 2022-10-282022-11-16 Journal: BMC Ecology and Evolution [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome animal hosts base bases bat bat coronavirus benefit Characteristics classical complex coronavirus determine Frame Future Genome genomic region hotspot Human human SARS-CoV-2 human SARS-CoV-2 strain INDEL Indel hotspot indels insertion/deletion insertion/deletion (indel). mechanism Multiple sequence alignment Mutation N-terminal domain Neutral non-structural protein Occurrence offer ORF8 ORF8 gene pangolin Pangolin coronavirus (PCoV) Point mutation RaTG13 Region reported RNA sequence S1 domain SARS-CoV SARS-CoV-2 SARS-related coronavirus SARS-related coronaviruses severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) survival the spike protein viral evolution virus viruses [DOI] 10.1186/s12862-022-02078-7 PMC 바로가기
Covid-19, an unfinished storyMini review Published on 2022-09-012022-10-05 Journal: La Presse Médicale [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] activities acute respiratory distress age amplitude bat coronavirus Beta Betacoronavirus caused China Cluster Comorbidities compulsory vaccination condition confirmed case coronavirus COVID-19 Critical cross deaths degree Delta detect development drug effective Efficacy epidemic waves epidemiological surveillance evade Face mask FIVE form Gamma Genome genomic Health highly pathogenic homogeneity Host Human immune response Immunity incidence rate include Inflammatory Innovation intensive care Measures Messenger RNA mild infection Moderna mRNA vaccine multiorgan failure nucleotides occupancy rate omicron Oxygen therapy pandemic Patient Pfizer-BioNTech Pneumonia preventing the transmission progressed Protective replaced RNA SARS-CoV-2 SARS-CoV-2 vaccine Sequencing severity syndrome the WHO thromboembolic complications Vaccine Vaccines variant variants variants of concern viral invasion VoC WHO World Health Organization [DOI] 10.1016/j.lpm.2022.104131 [Article Type] Mini review
The Genetic Characterization of the First Detected Bat Coronaviruses in Poland Revealed SARS-Related Types and AlphacoronavirusesArticle Published on 2022-08-302022-11-15 Journal: Viruses [Category] SARS, 치료기술, [키워드] 95% CI alphacoronavirus alphaCoV bat bat coronavirus bats characterization collected coronavirus Coronaviruses COVID-19 distribution European European country fecal Fecal sample highlight Host identity Molecular epidemiology Myotis oral swab Phylogenetic phylogenetics Poland Prevalence Revealed Rhinolophidae SARS-related coronavirus SARS-related CoV Type virus was determined [DOI] 10.3390/v14091914 PMC 바로가기
Cross-Neutralization of SARS-CoV-2-Specific Antibodies in Convalescent and Immunized Human Sera against the Bat and Pangolin Coronaviruses박쥐 및 천산갑 코로나바이러스에 대한 회복기 및 면역화된 인간 혈청에서 SARS-CoV-2-특이적 항체의 교차 중화Article Published on 2022-08-162022-09-12 Journal: Viruses [Category] SARS, 진단, [키워드] ACE2 analyzed appear bat bat coronavirus binding Cell cell-cell fusion chimeric chimeric proteins contribute coronavirus COVID-19 COVID-19 patient cross-neutralize highest Human human ACE2 receptor human host immunized inactivated induce less neutralization neutralization activity neutralized Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody overexpressing pandemic pangolin pangolin coronavirus pangolins pre-existing immunity promote Protein pseudo-virus pseudo-virus. RaTG13 RBD replaced sarbecovirus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine serum sample significantly significantly higher spike the RBD the receptor-binding domain thought transmitted vaccination VeroE6 cells while widespread [DOI] 10.3390/v14081793 PMC 바로가기 [Article Type] Article
Sequence Exchange Involving Dozens of Consecutive Bases with External Origin in SARS-Related CoronavirusesArticle Published on 2022-08-102023-07-10 Journal: Journal of Virology [Category] COVID19(2023년), [키워드] bat coronavirus deletion-with-insertion insertion and/or deletion severe acute respiratory syndrome coronavirus (SARS-CoV). [DOI] 10.1128/jvi.01002-22 PMC 바로가기
Bat coronaviruses related to SARS-CoV-2: what about their 3CL proteases (MPro)?Article Published on 2022-04-132023-07-02 Journal: Journal of Enzyme Inhibition and Medicinal Chemist [Category] COVID19(2023년), SARS, [키워드] BANAL bat coronavirus Laos MPro Paxlovid sarbecovirus SARS-CoV-2 [DOI] 10.1080/14756366.2022.2062336 PMC 바로가기
CD4 + T cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronavirusesClinical Trial Published on 2022-03-012022-10-04 Journal: The Journal of Clinical Investigation [Category] MERS, SARS, 임상, [키워드] Adaptive immunity assays bat coronavirus bat coronaviruses BNT162b2 CD4 common cold Coronaviruses conserved coronavirus Coronaviruses COVID-19 COVID-19 vaccines demonstrated elicit Endemic epitope homologous Hypothesis induce majority MERS-CoV Moderna mRNA vaccine mRNA-1273 Outbreaks Pandemics participant peptide Pfizer-BioNTech recent recipient recognize Responder SARS-CoV SARS-CoV-2 SARS-CoV-2 spike protein Sequencing shown Support T cell T cell receptor T cell response vaccinated individual Vaccine zoonotic [DOI] 10.1172/JCI156083 PMC 바로가기 [Article Type] Clinical Trial
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice광범위 교차 반응성 항체는 마우스에서 사베코바이러스 공격을 중화하고 보호합니다.Article Published on 2022-02-232022-09-14 Journal: Science Translational Medicine [Category] SARS, 변종, 진단, 치료제, [키워드] acute respiratory syndrome against SARS-CoV antibody B.1.1.7 B.1.351 B.1.429 B.1.526 B.1.617.1 B.1.617.2 bat coronavirus binding caused conserved coronavirus cross-reactive antibody D614G domain effective epitope events high affinity in vivo Infection infections mice mitigate Mortality neutralization neutralize outbreak P.1 Prevent PROTECT Protective RBD RsSHC014 sarbecovirus Sarbecoviruses SARS-CoV SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-related viruses strain Structural analysis Therapeutic treatment Vaccine zoonotic [DOI] 10.1126/scitranslmed.abj7125 PMC 바로가기 [Article Type] Article