Evaluating correlates of protection for mix-match vaccine against COVID-19 VOCs with potential of evading immunityArticle Published on 2022-11-082022-11-15 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] appear Bayesian Beta ChAdOx1 Clinical efficacy Correlate of protection COVID-19 D614G Delta Delta VOC distribution Efficacy ENhance evaluate Evaluating finding Heterologous highlight homologous Immunity inversion Mix-match mRNA-1273 neutralizing antibody omicron pandemic phase 3 trial predicted Predictive previous study provide ranged reduction reductions in strain vaccination Vaccine variant Variant of concern. variants variants of concern VoC VOCs was used while Wuhan [DOI] 10.1016/j.vaccine.2022.10.011 PMC 바로가기
Onset and window of SARS-CoV-2 infectiousness and temporal correlation with symptom onset: a prospective, longitudinal, community cohort studyArticle Published on 2022-11-012022-11-15 Journal: The Lancet. Respiratory Medicine [Category] SARS, 변종, 치료기술, [키워드] accelerate Alpha assessment assumption Bayesian Cohort cohort study Community Contact correlation Course COVID-19 COVID-19 case determine diagnosed early diagnosis eight eligible enrolled Evidence Final Guidance Hierarchical High-resolution household index cases Infection infection control Infectious virus initial IQR Isolation kinetic Lateral flow device LFD median Older Onset participant PCR positive PCR-confirmed plaque-forming unit post-symptom onset Probability quantified real-world data recruitment reduced released RT-PCR SARS-CoV-2 Self-isolation sensitivity Seven study population suggested Support survival Symptom symptom onset Symptoms the median the SARS-CoV-2 to define Transmission upper respiratory tract variant viral growth Viral load viral replication Viral RNA viral RNA load viral shedding virus were assessed [DOI] 10.1016/S2213-2600(22)00226-0 PMC 바로가기
Comparative effectiveness of neutralising monoclonal antibodies in high risk COVID-19 patients: a Bayesian network meta-analysisArticle Published on 2022-10-202022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), meta-analysis, SARS, 변종, 진단, [키워드] absolute reduction article baseline Bayesian comparable Comparative COVID-19 Effect effective Effectiveness Efficacy Evidence expected generalisability healthcare high risk hospitalisation ICU admission identify individual infected individual infected with SARS-CoV-2 invasive ventilation moderate monoclonal antibody Mortality network Network meta-analysis neutralising outcome Pairwise comparison patient population patients patients treated Placebo predict Rate RCT reaction reduce mortality reducing reduction in relative risk risk reduction serious AE severe COVID-19 statistically significant reduction systematic review therapy treatment effect vaccination variant [DOI] 10.1038/s41598-022-22431-6 PMC 바로가기
Evaluating diagnostic accuracies of Panbio™ test and RT-PCR for the detection of SARS-CoV-2 in Addis Ababa, Ethiopia using Bayesian Latent-Class Models (BLCM)Article Published on 2022-10-192022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Accuracy Ag-RDTs Bayesian clinical setting cough COVID-19 COVID-19 pandemic CrI criteria cross-sectional diagnostic diagnostic sensitivity diagnostics enrolled evaluate Evaluating exhibited expected females health center hospitals individual majority Model MOST pandemic Patient performed positive positive RT-PCR Rapid rapid antigen test Rapid diagnostic test reference standard reported RT-PCR SARS-CoV-2 sensitivity specificity Study participants symptomatic and asymptomatic the WHO Transmission was done without symptoms [DOI] 10.1371/journal.pone.0268160 PMC 바로가기
A multicenter, double-blind, randomized, parallel-group, placebo-controlled study to evaluate the efficacy and safety of camostat mesilate in patients with COVID-19 (CANDLE study)Article Published on 2022-09-272022-11-15 Journal: BMC Medicine [Category] SARS, 진단, [키워드] 95% confidence interval Administered age airway analysis asymptomatic patients Bayesian camostat camostat mesilate cardiovascular diseases cells Chronic kidney disease chronic respiratory disease clinical conducted consecutive negative test conversion COVID-19 COVID-19 symptom Diabetes Mellitus dose double-blind Drug screening effective Efficacy and safety eight enrolled evaluate Factor first test hospital human airway epithelial hypertension indicated Japan median time Mild moderate multicenter no significant difference obesity parallel-group Patient patients patients with COVID-19 Placebo placebo-controlled study Positive test Prevent primary efficacy endpoint Randomized Randomized controlled trial receive reduce registry SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. the placebo group the primary endpoint Treatment two groups underlying disease viral clearance viral loads was performed were blinded were excluded without symptoms [DOI] 10.1186/s12916-022-02518-7 PMC 바로가기
Trend of hand, foot, and mouth disease from 2010 to 2021 and estimation of the reduction in enterovirus 71 infection after vaccine use in Zhejiang Province, ChinaArticle Published on 2022-09-202022-11-16 Journal: PLoS ONE [Category] 치료기술, [키워드] Administered age Analysis APC average Bayesian biennial caused changes in Characteristics China COVID-19 epidemic death demographic characteristics disease distributions effective excluded expected incidence incidence rate individual Infection information measure pathogen promoted reduction in Regression model reported shown Surveillance trend vaccination Vaccine Variation virus virus was used were used Yangtze River Delta Zhejiang [DOI] 10.1371/journal.pone.0274421 PMC 바로가기
Effects of intravesical BCG maintenance therapy duration on recurrence rate in high-risk non-muscle invasive bladder cancer (NMIBC): Systematic review and network meta-analysis according to EAU COVID-19 recommendationsArticle Published on 2022-09-082022-11-16 Journal: PLoS ONE [Category] meta-analysis, [키워드] appear Bayesian BCG Bladder cancer can be used chain conducted coronavirus disease Course COVID-19 COVID-19 pandemic demonstrated Effect effective European forest plot group groups highest intravesical invasive item Markov material Network meta-analysis no difference pandemic Patient receiving recommendation recommendations Reporting review systematic review therapy Treatment Urology was performed [DOI] 10.1371/journal.pone.0273733 PMC 바로가기
High seroprevalence of SARS-CoV-2 in Burkina-Faso, Ghana and Madagascar in 2021: a population-based studyArticle Published on 2022-09-052022-11-15 Journal: BMC Public Health [Category] SARS, 변종, 진단, [키워드] accounted acute infections acute SARS-CoV-2 infection adjusted Affect African age Assessing Bayesian Bayesian model Characteristics Cluster conducted Consequences country COVID-19 pandemic CrI evaluated Fianarantsoa Health Herd immunity threshold highlight IgG interval less logistic regression model MONITOR naturally acquired immunity new virus pandemic participant Participants performed Population population-based prevalence of COVID-19 preventive measure progression PROTECT Region risk SARS-CoV-2 SARS-CoV-2 seroprevalence serological survey Seroprevalence Sex specificity Spread study population Sub-Saharan Africa. the epidemic Vaccine variant was determined [DOI] 10.1186/s12889-022-13918-y PMC 바로가기
A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation고염증을 동반한 COVID-19 폐렴의 치료를 위한 Clazakizumab의 무작위 이중 맹검 위약 대조 시험Clinical Trial Published on 2022-09-012022-09-12 Journal: Critical Care Medicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 1:1 accompanied added Bayesian benefit board changes Clazakizumab Clinical outcome clinical status Controlled COVID-19 COVID-19 disease Critical cumulative double-blinded dropped enrolled Frequency greater High-dose hospitalized patient hyperinflammation ICU ICU admission inhibitor Inpatient interleukin-6 intubation Logistic low-dose measurement monitoring Odds ratio outcome Patient patients patients hospitalized Placebo placebo-controlled Poisson regression model Primary outcome Randomized receiving recommendations risk Safety seamless secondary secondary outcome severe COVID-19 disease significantly suggested survival Trial Ventilation ventilator-free survival were used with COVID-19 [DOI] 10.1097/CCM.0000000000005591 PMC 바로가기 [Article Type] Clinical Trial
Remdesivir for the treatment of COVID-19: a systematic review and meta-analysisReview article Published on 2022-09-012022-10-05 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 임상, 치료법, [키워드] 95% CI assessment Bayesian benefit clinically conducted coronavirus COVID-19 criteria eight eligibility criteria evaluate Hospitalized hospitalized patient Inpatient mechanical ventilation Meta-analysis Mortality Neutral objective oxygen Oxygen requirements participant Participants Patient patients with COVID-19 performed Placebo Primary outcome Probability random effect randomized trials recommendation reduce reduced Remdesivir requiring supplemental oxygen Result risk risk of bia risk reduction searched Standard of care stratified supplemental oxygen systematic review the patient therapy Treatment with COVID-19 World Health Organization [DOI] 10.1016/j.cmi.2022.04.018 [Article Type] Review article