Gut microbiota-derived synbiotic formula (SIM01) as a novel adjuvant therapy for COVID-19: An open-label pilot studyCOVID-19에 대한 새로운 보조 요법으로서 장내 미생물총 유래 신바이오틱 포뮬라(SIM01): 오픈 라벨 파일럿 연구Article Published on 2022-05-012022-09-12 Journal: Journal of gastroenterology and hepatology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Admission Analysis antibody formation Antibody Response bacterial specy bifidobacteria changes in commensal bacteria Control control group controls COVID-19 COVID-19 patient database Day develop discharge Effect fecal greater Gut gut microbiota healthy Hong Kong hospital hospitalised COVID-19 patients hospitalized COVID-19 patients IgG antibody IL-1ra immune dysfunction immune markers Immunity Immunological response IMPROVE independent Infectious disease Intervention M-CSF Macrophage MCP-1 metagenomic microbiota monocyte chemoattractant protein-1 nasopharyngeal nasopharyngeal viral load Necrosis Open-label outcome pathogen Patient pilot study plasma positive pro-inflammatory probiotics. proinflammatory protocol receive receiving reduced restored SARS-CoV-2 SARS-CoV-2 IgG antibody SARS-CoV-2 viral load severity of COVID-19 significant negative correlation significantly standard treatment Strains suggested therapy TNF-α were given [DOI] 10.1111/jgh.15796 PMC 바로가기 [Article Type] Article
Lost microbes of COVID-19: Bifidobacterium, Faecalibacterium depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severityArticle Published on 2022-04-012023-07-09 Journal: BMJ open gastroenterology [Category] COVID19(2023년), [키워드] Bacterial infection bifidobacteria enteric bacterial microflora intestinal microbiology. [DOI] 10.1136/bmjgast-2022-000871 PMC 바로가기
The Role of the PFNA Operon of Bifidobacteria in the Recognition of Host’s Immune Signals: Prospects for the Use of the FN3 Protein in the Treatment of COVID-19숙주의 면역 신호 인식에서 비피도박테리아의 PFNA 오페론의 역할: COVID-19 치료에서 FN3 단백질의 사용에 대한 전망Review Published on 2021-08-262022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 유전자 메커니즘, [키워드] addressed anti-inflammatory drug Anti-inflammatory drugs Bacteria bifidobacteria binding Cluster consequence core genes COVID-19 creation cytokine cytokine receptor Cytokine storms domain domains Evolution FIVE host immune system host-microbe interaction humans immune system immunomodulatory properties immunomodulatory property implicated implication Interaction mechanism microbial motif motifs operon over PFNA operon Protein protein kinase question Recognition resulting role SARS-COV-2 infection Serine species threonine TNF-α transmembrane region [DOI] 10.3390/ijms22179219 PMC 바로가기 [Article Type] Review
Gut Dysbiosis during COVID-19 and Potential Effect of ProbioticsReview Published on 2021-07-282022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Bifidobacteria Lactobacillus ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 Antiviral effect association bifidobacteria binding cause cell entry characterized clinical trial Complication coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 severity dietary supplement disease Dysbiosis Effect effective Efficacy Evidence evidenced exhibiting expressed family Coronaviridae fecal gastrointestinal involvement Gut gut microbiome Health homeostasis IMPROVE infect Inflammation intestinal lactobacillus lung oral pathogen Potential Probiotics receptor RNA virus SARS-CoV-2 SARS-COV-2 infection Spike protein target therapeutic therapy tissues transmembrane protein Transmission treating COVID-19 treating COVID-19 patient [DOI] 10.3390/microorganisms9081605 PMC 바로가기 [Article Type] Review
Human Milk Oligosaccharides: Health Benefits, Potential Applications in Infant Formulas, and PharmacologyArticle Published on 2020-01-202023-08-30 Journal: Nutrients [Category] E형 간염, [키워드] bifidobacteria human milk oligosaccharides infections nutrition prebitics [DOI] 10.3390/nu12010266 PMC 바로가기 [Article Type] Article
Microbial Monitoring of Surface Water in South Africa: An OverviewReview Published on 2012-07-302023-08-30 Journal: International Journal of Environmental Research an [Category] E형 간염, [키워드] E. coli bifidobacteria H2S strip test national microbial monitoring programme [DOI] 10.3390/ijerph9082669 PMC 바로가기 [Article Type] Review