Association between heme oxygenase one and sepsis development in patients with moderate-to-critical COVID-19: a single-center, retrospective observational studyObservational Study Published on 2022-12-042023-07-10 Journal: European Journal of Medical Research [Category] COVID19(2023년), [키워드] Bilirubin COVID-19 ferritin heme Heme oxygenase one sepsis. [DOI] 10.1186/s40001-022-00915-5 PMC 바로가기 [Article Type] Observational Study
Type D lymphomatoid papulosis with pityriasis lichenoides et varioliformis acuta-like features in a child with parvovirus infection: a controversial diagnosis in the spectrum of lymphoid proliferations: case report and literature reviewArticle Published on 2022-10-282022-11-16 Journal: Italian Journal of Pediatrics [Category] COVID19(2023년), SARS, 치료기술, [키워드] Administered Alanine antigenic Aspartate aminotransferase Bilirubin C-reactive protein Case report CD8+/CD30+ cells children clinical response clinical suspicion Critical cytokine profile Cytokines Department Diagnosis differential diagnosis discharged disease disorder Emergency erythematous feature Fever histological history Hospitalized IFN-γ IL-10 IL-6 immunoglobulin M infectious agent infiltration introduced Laboratory test lesion lesions limits literature review lymphoid lymphomatoid Lymphomatoid papulosis lymphoproliferative Lymphoproliferative cutaneous disorders marker mechanism monoclonal morphologically necrotic Parvovirus parvovirus B19 pathogenic Perspective phenotype pityriasis lichenoides et varioliformis acuta. polymerase chain reaction positive response proliferation Rash recorded regions reported representing returned SARS-CoV-2 antigen separated skin lesions steroid Support Symptom systemic corticosteroid T-cell receptor Therapies Treatment Type Type D [DOI] 10.1186/s13052-022-01371-x PMC 바로가기
Pilot study of home phototherapy for neonatal jaundice monitored in maternity ward during the enforced Italy-wide COVID-19 national lockdownObservational Study Published on 2022-09-012022-10-05 Journal: European journal of pediatrics [Category] 임상, [키워드] abnormality administer Bilirubin Breastfeeding Care carried Course COVID COVID-19 COVID-19-enforced lockdown decrease defined discharge effective Efficacy equipment evaluated Evidence Follow-up Health help Hill home Home phototherapy hospital hospitals HPT Infant Infants Infection involved Italy lockdown mother National Neonatal neonatal jaundice Neonate occurred parent parental Patient performed phototherapy Phototherapy. pilot study Policlinic potential benefit readmission reduction required Safe Satisfaction serum Support supported temperature Treatment zone [DOI] 10.1007/s00431-022-04557-x PMC 바로가기 [Article Type] Observational Study
Severe refractory warm autoimmune haemolytic anaemia after the SARS-CoV-2 Pfizer-BioNTech vaccine (BNT162b2 mRNA) managed with emergency splenectomy and complement inhibition with eculizumabArticle Published on 2022-08-312022-11-15 Journal: BMJ case reports [Category] SARS, 진단, [키워드] 48 hour Autoimmune Bilirubin Blood BNT162b2 mRNA Chest complement Complement pathway Corticosteroid described disease eculizumab fatigue first dose haematology (incl blood transfusion) Haemoglobin highlight inhibitor initiated investigation jaundice lactate dehydrogenase life-threatening liver male over Pfizer-BioNTech SARS-CoV-2 standard treatment the patient the SARS-CoV-2 transplantation transplantation. Urine Vaccine warm was performed [DOI] 10.1136/bcr-2022-250774 PMC 바로가기
A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severityObservational Study Published on 2022-08-302022-10-05 Journal: Nature Communications [Category] 바이오마커, 임상, 진단, 치료법, [키워드] age Bilirubin Biomarker Brain C-reactive protein chronic fatigue syndrome Cohort Coronavirus disease 2019 COVID-19 evaluate fatigue ferritin Germany hand healthy hemoglobin Inflammation laboratory parameter long-lasting male median age Mild moderate MOST N-terminal Non-COVID-19 pandemic Pathomechanisms Patient patients peptide Postinfectious prohormone prospective observational cohort prospective observational study severe fatigue severity subset Symptom symptom burden symptom severity syndrome [DOI] 10.1038/s41467-022-32507-6 PMC 바로가기 [Article Type] Observational Study
Real-World Evidence for COVID-19 Delta Variant’s Effects on the Digestive System and Protection of Inactivated Vaccines from a Medical Center in Yangzhou, China: A Retrospective Observational StudyObservational Study Published on 2022-08-192022-10-04 Journal: International journal of clinical practice [Category] SARS, 바이오마커, 변종, 임상, [키워드] addition Affect alanine aminotransferase ALT analysis of variance ANOVA AST Bilirubin biochemical center changes in Chinese Cohort Coronavirus disease 2019 COVID-19 Critical Critical disease Delta delta variant diagnosed digestive system dysfunction early stage Effect evaluate function Gastrointestinal symptom global public health IL-6 level Inactivated vaccine inactive Infection interleukin 6 (IL-6 investigated lactate dehydrogenase LDH liver dysfunction marker mild illness moderate no significant difference p value Patient prevalent Prevent promoted PROTECT protection public health reported respiratory tract retrospective serum severity Significant significant difference significantly more Sinopharm Sinovac statistically significant Symptom System three group three groups total bilirubin Treatment Vaccine variant was used [DOI] 10.1155/2022/7405448 PMC 바로가기 [Article Type] Observational Study
Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndromeObservational Study Published on 2022-05-232022-10-05 Journal: Critical Care [Category] 임상, [키워드] acute respiratory distress adjusted Analysis ARDS Bilirubin Chemical Chemical and drug-induced liver injury Cholangiopathy Cholangitis cholestasis competing confidence interval COVID-19 patient COVID-19 patients COVID-19-associated ARDS Critically ill Critically ill patient cumulative doses High-dose Hypnotics and sedatives. ICU incidence infused Ketamine liver Liver injury mechanically ventilated mechanically ventilated patient mixed-effects model multivariable Patient positively correlated Post hoc analysis propofol prospective observational cohort receiving regimen rising risk Sedation shown syndrome total bilirubin [DOI] 10.1186/s13054-022-04019-8 PMC 바로가기 [Article Type] Observational Study
Late Onset of ANCA Vasculitis as a Side Effect of Levamisole Treatment in Nephrotic Syndrome신증후군에서 Levamisole 치료의 부작용으로 ANCA 혈관염의 늦은 발병Case Reports Published on 2022-05-112022-09-11 Journal: Medicina [Category] MERS, 바이오마커, 진단, [키워드] Administered affected age alterations ANCA-vasculitis antibody Arthritis autoantibody Awareness Bilirubin Case report celiac disease children circulating clinical manifestation clinical manifestations clinician cocaine cocaine abuse COVID-19 vaccine cumulative cytopenia cytoplasmic decrease demonstrated diagnosed direct bilirubin disease dose drug reaction Effect Fever foot hand high fever induce initial injection joint lack Levamisole liver enzyme liver enzymes manifestation MPO myeloperoxidase nephrotic syndrome nephrotic syndrome. nine Onset positive raise receive reduction in reported returned second dose secondary to side Side effect Side effects steroid Symptom Symptoms syndrome the patient total and direct bilirubin treated Treatment vaccination Vasculitis was measured [DOI] 10.3390/medicina58050650 PMC 바로가기 [Article Type] Case Reports
Association of the IL-6R gene polymorphic variant rs2228145(C>A) with IL-6 gene polymorphisms in a healthy cohort of Turkish population Research Published on 2022-04-012022-10-05 Journal: Genes and Immunity [Category] 바이오마커, 유전자 메커니즘, [키워드] age allele allele G allelic association Bilirubin BMI body mass index Cohort collected Comorbidity Concentration Diseases evaluated explained fasting insulin Folic acid Frequency Gender Globulin healthy hematological parameters hormone IL-6 IL-6R IL-6R gene individuals Laboratory laboratory data laboratory parameter Liver function test loci locus majority monocyte neutrophil Platelets polymorphic variant polymorphism renal rs2228145 SHBG significantly higher significantly lower subject uric acid variant Variation White blood cells [DOI] 10.1038/s41435-022-00167-7 [Article Type] Research
SARS-CoV-2 Infects Red Blood Cell Progenitors and Dysregulates Hemoglobin and Iron MetabolismSARS-COV-2는 적혈구 전구체를 감염시키고 헤모글로빈과 철 대사를 조절시킨다Article Published on 2022-02-182022-09-10 Journal: Stem cell reviews and reports [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] accompanied ACE2 receptor acute respiratory distress aggravate Alpha analyzed Anemia Bilirubin Blood Blood samples cause CD147 Cell cells Coagulopathies Coagulopathy concentrations contribute Course COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients death Degradation diagnostic differentiation door dysregulation erythroid Erythroid precursors expansion Express ferritin HAMP healthy donor healthy donors heme hemoglobin Hemoglobin biosynthesis Hemoglobin degradation hepcidin homeostasis hospitalized COVID-19 patient hospitalized COVID-19 patients hypoxia identify impair in vitro infect inhibit iron Iron metabolism mass spectrometry metabolism Mortality mRNA expression multiorgan failure opens oxygen Peripheral blood precursor progenitor qPCR analysis Raman Trapping Microscopy RBC RBCs Red red blood cell red blood cells reduced respiratory distress Result SARS-CoV-2 SARS-COV-2 infection serum Serum ferritin severe COVID-19 disease severely ill COVID-19 patients severity Spectroscopy stem cell stem cells susceptible Therapeutic strategies total bilirubin Transferrin variant were infected Whole blood Zinc [DOI] 10.1007/s12015-021-10322-8 PMC 바로가기 [Article Type] Article