Feline coronavirus influences the biogenesis and composition of extracellular vesicles derived from CRFK cellsVeterinary Science Original Research Published on 2024-07-182024-09-05 Journal: Frontiers in Veterinary Science [Category] update2024, [키워드] biogenesis CRFK cells Exosomes Extracellular vesicles Feline coronavirus immunomodulation pandemic [DOI] 10.3389/fvets.2024.1388438 PMC 바로가기 [Article Type] Veterinary Science Original Research
Biogenesis and delivery of extracellular vesicles: harnessing the power of EVs for diagnostics and therapeuticsMolecular Biosciences Mini Review Published on 2024-01-032024-09-05 Journal: Frontiers in Molecular Biosciences [Category] update2024, [키워드] biogenesis delivery ectosomes Exosomes Extracellular vesicles network analysis uptake [DOI] 10.3389/fmolb.2023.1330400 PMC 바로가기 [Article Type] Molecular Biosciences Mini Review
Biogenesis, Composition and Potential Therapeutic Applications of Mesenchymal Stem Cells Derived Exosomes in Various DiseasesReview Published on 2023-06-142024-09-05 Journal: International journal of nanomedicine [Category] update2024, [키워드] Angiogenesis Autoimmune disease biogenesis Exosomes extracellular vesicle Mesenchymal stem cells [DOI] 10.2147/IJN.S407029 PMC 바로가기 [Article Type] Review
Exosomes: a potential diagnostic and treatment modality in the quest for counteracting cancerReview Published on 2023-04-112024-09-05 Journal: Cellular oncology (Dordrecht) [Category] update2024, [키워드] biogenesis Biomarkers Cancer Exosomes Isolation [DOI] 10.1007/s13402-023-00810-z PMC 바로가기 [Article Type] Review
Effects of Human Nucleolus Upon Guest Viral-Life, Focusing in COVID-19 Infection: A Mini- ReviewReview Article Published on 2022-12-152022-10-29 Journal: Iranian Journal of Pathology [Category] COVID-19, [키워드] accumulating biogenesis Cell cell stress concerning coronavirus disease Coronavirus infections COVID-19 DDR disrupt DNA damage Effect endotheliopathy eukaryotic cells Evidence Focusing function gene silencing Human human diseases MINI nucleoli Nucleolopathy Nucleolus nucleus organism Organisms pathogenic precursor Protein provided Regulation Replication review subcellular tRNA viral infection viral infections virus [DOI] 10.30699/IJP.2021.540305.2744 PMC 바로가기 [Article Type] Review Article
Reconstructed Genome-Scale Metabolic Model Characterizes Adaptive Metabolic Flux Changes in Peripheral Blood Mononuclear Cells in Severe COVID-19 PatientsArticle Published on 2022-10-172022-11-15 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제, [키워드] acute respiratory syndrome adaptive aerobic Analysis anti-inflammatory effect antiviral drugs biogenesis caused change changes in Coronavirus disease 2019 Coronavirus-2 COVID-19 differentially expressed enzyme FASN fatty flux Glycolysis Health Immune cell Inflammation Inflammatory lipids mechanism metabolic metabolic model metabolism metabolism-directed therapy. metabolites Model mononuclear cell nucleotide oxidative phosphorylation pathogenic PBMC PBMCs peripheral Peripheral blood potential therapeutic targets provide reaction reconstructed Regulation responsible retinol SARS-CoV-2 severe COVID-19 patients SLC2A3 therapy Transcriptome Treatment Vitamin [DOI] 10.3390/ijms232012400 PMC 바로가기
Morphological, cellular, and molecular basis of brain infection in COVID-19 patients코로나19 환자 뇌 감염의 형태적, 세포적, 분자적 기초Article Published on 2022-08-302022-09-11 Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alteration anxiety symptoms Astrocyte astrocytes biogenesis Brain brain damage Brain infection brain tissue brains cellular changes in characterized Cohort contribute coronavirus cortical Cortical atrophy COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients death deregulated died dysfunction elicit energy metabolism Evidence exhibited fatigue FIVE foci functional genetic material guide histopathological sign histopathological signs Hypothesis impairment in vitro independent individual infect infected individual Infection Interaction manifestation manifested mechanism metabolism metabolite metabolites mild infection molecular basis neural stem cell Neurological symptoms neuronal neurons Neuropsychiatric Neurotransmitters NRP1 Patient phenotype Protein reduce Replication SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus Severe COVID-19 Infection Spectrum Support Supporting susceptible syndrome tissue sample viability virus [DOI] 10.1073/pnas.2200960119 PMC 바로가기 [Article Type] Article
The double-membrane vesicle (DMV): a virus-induced organelle dedicated to the replication of SARS-CoV-2 and other positive-sense single-stranded RNA viruses이중막 소포(DMV): SARS-CoV-2 및 기타 포지티브 센스 단일 가닥 RNA 바이러스 복제 전용 바이러스 유도 소기관Review Published on 2022-07-162022-09-11 Journal: Cellular and Molecular Life Sciences [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analogy Antiviral approach autophagic biogenesis can not Cell organelle coronavirus COVID-19 Double-membrane vesicle Endoplasmic reticulum export Genome Golgi apparatus HCV hepatitis C hepatitis C virus host cell host cell membrane host cell membranes induce initial Innate immunity interactions involved lipid droplet lipid droplets lipids mechanism mechanisms membrane metabolite metabolites Mitochondria morphology non-structural protein organelle other coronavirus other coronaviruses pathogen phylogenetically positive-sense single-stranded RNA Positive-sense single-stranded RNA virus Replication replication of SARS-CoV-2 Replication organelle required RNA RNA virus SARS-CoV-2 sealed shown similarity single-stranded storage supply these viruses Vesicle viral replication Viral RNA virions virus Virus/cell interactions. viruses [DOI] 10.1007/s00018-022-04469-x PMC 바로가기 [Article Type] Review
MicroRNAs in the development of potential therapeutic targets against COVID-19: A narrative reviewReview article Published on 2022-07-012022-10-05 Journal: Journal of infection and public health [Category] COVID19(2023년), SARS, 바이오마커, 변종, 치료제, [키워드] ACE2 ACE2 receptor ACE2 receptors Antiviral biogenesis cellular miRNAs change chemokines collected complex conducted consequence COVID-19 cytokine Cytokines database Degradation Deleterious effective evaluate expression Extensive function generate Google help host response immune system include Infection infection process information inhibiting Interaction involved latency microRNA miRNA miRNAs Modification modulate Pathogenesis platform potential therapeutic target Prognosis reduce reduced regimen Regulation Regulatory Result SARS-CoV-2 SARS-COV-2 infection Science Direct Scientific community secretion Side effects Specific the SARS-CoV-2 therapeutic therapeutic target therapeutic targets Therapeutics therapy threat viral infection Viral load viral replication Viral RNA virus website WHO [DOI] 10.1016/j.jiph.2022.06.012 [Article Type] Review article
SARS-CoV-2 ORF7a potently inhibits the antiviral effect of the host factor SERINC5SARS-CoV-2 ORF7a는 숙주 인자 SERINC5의 항바이러스 효과를 강력하게 억제합니다Article Published on 2022-05-262022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome coronavirus Antiviral effect biogenesis Cell fusion cellular coronavirus 2 counteract evaluated expressed Factor HIV Host Human Human immunodeficiency virus immunodeficiency virus incorporation information inhibit involved ORF7a Protein respiratory restrict retroviruses SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection SERINC5 Serine severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 sphingolipid transmembrane protein turn virion virions virus infectivity while [DOI] 10.1038/s41467-022-30609-9 PMC 바로가기 [Article Type] Article