Aloe vera ―An Extensive Review Focused on Recent StudiesReview Published on 2024-07-082024-09-05 Journal: Foods [Category] update2024, [키워드] Aloe vera L. biological activities Chemical composition toxicological aspects [DOI] 10.3390/foods13132155 PMC 바로가기 [Article Type] Review
A comprehensive review on nutritional, nutraceutical, and industrial perspectives of perilla ( Perilla frutscens L.) seeds – An orphan oilseed cropReview Article Published on 2024-06-182024-09-05 Journal: Heliyon [Category] update2024, [키워드] biological activities Blending Industrial applications Perilla phytochemicals [DOI] 10.1016/j.heliyon.2024.e33281 PMC 바로가기 [Article Type] Review Article
Characterization of anti-SARS-CoV-2 monoclonal antibodies focusing on antigen binding, neutralization, and FcγR activation via formation of immune complexReport Published on 2023-06-122024-09-05 Journal: mAbs [Category] update2024, [키워드] biological activities COVID-19 Fcγ receptor Immune complexes mAbs SARS-CoV-2 [DOI] 10.1080/19420862.2023.2222874 PMC 바로가기 [Article Type] Report
Chemistry and Biological Activities of Naturally Occurring and Structurally Modified PodophyllotoxinsReview Published on 2022-12-302023-07-11 Journal: Molecules [Category] COVID19(2023년), [키워드] Antitumor Antiviral biological activities podophyllotoxin structural modification. [DOI] 10.3390/molecules28010302 PMC 바로가기 [Article Type] Review
Diagnostic and Therapeutic Potential for HNP-1, HBD-1 and HBD-4 in Pregnant Women with COVID-19COVID-19에 감염된 임산부에서 HNP-1, HBD-1 및 HBD-4에 대한 진단 및 치료 가능성Article Published on 2022-03-222022-09-11 Journal: International Journal of Molecular Sciences [Category] 유전자 메커니즘, [키워드] affected Alpha AMPs anti-inflammatory cytokine antimicrobial peptide antimicrobial peptides Beta Biochemistry biological activities characterized Coagulation Confirmed COVID-19 infection COVID-19 COVID-19 infection cytokine cytokine profile Cytokines defensin Defensins deficiency defined ELISA assay evaluated fetus Gene Expression generate help highlight IL-10 IL-2 IL-6 IL-8 immune immune system immunological change increase in Infection innate immune system Interleukins involved Laboratory Laboratory medicine lipoprotein lipoprotein-a mechanism mother peptides Potential Pregnancy pregnant women pro-inflammatory factor pro-inflammatory factors problem problems PROTECT risk factor TGF-β TNF-α virus attacks Vitamin vitamins with COVID-19 [DOI] 10.3390/ijms23073450 PMC 바로가기 [Article Type] Article
Investigation of angucycline compounds as potential drug candidates against SARS Cov-2 main protease using docking and molecular dynamic approaches도킹 및 분자 동적 접근법을 사용하여 SARS COV-2 메인 프로테아제에 대한 잠재적 약물 후보로서 Angucycline 화합물의 조사Article Published on 2022-02-012022-08-31 Journal: Molecular diversity [Category] COVID19(2023년), SARS, 치료제, [키워드] 3CLpro Angucycline compounds Antibacterial anticancer Antiviral approach binding affinity binding energy biological activities biological activity cause co-crystallized Compound coronavirus coronavirus disease COVID-19 disease docking drug candidate drug design Drug discovery effective Effectiveness in vitro in vivo inhibitors investigation Ligand main protease MM-PBSA molecular molecular dynamics Molecular dynamics simulation molecular interaction Molecular modelling. produced protease Research resource respiratory respiratory tract infection SARS CoV-2 Streptomyce target the binding affinity Treatment Viral viral infection [DOI] 10.1007/s11030-021-10219-1 PMC 바로가기 [Article Type] Article
Potential Antiviral Action of AlkaloidsReview Published on 2022-01-282022-10-30 Journal: Molecules [Category] COVID-19, [키워드] acting Action alkaloid alkaloids Antiviral antiviral activity antiviral agent antiviral drug antiviral therapeutics biological activities cause Characteristics Concentration DNA DNA and RNA Effect effective Efficacy Efficiency effort Evidence highlight humans identify Infection inhibition inhibitory concentration molecular morbidity and mortality natural products outbreak Pandemics plants Potential protein synthesis public health emergency Research RNA Safe specificity targets Treatment Vaccine Viral diseases viral entry viral replication virus viruses [DOI] 10.3390/molecules27030903 PMC 바로가기 [Article Type] Review
The Swine IFN System in Viral Infections: Major Advances and Translational ProspectsReview Published on 2022-01-272022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] advance affected Anti-inflammatory Antiviral antiviral immune response binding biological activities cytokine Defense DNA virus effector mechanisms elicit Host IFN IFN response IFNs Immune escape immunomodulatory innate immune response interferons involved Major mechanism mechanisms modulate pig plethora receptors Replication representing RNA signaling cascade System Transcription Treatment strategies viral infection viral infections virus [DOI] 10.3390/pathogens11020175 PMC 바로가기 [Article Type] Review
Synthetic approaches to 1,2,4-triazolo[5,1-c][1,2,4]triazin-7-ones as basic heterocyclic structures of the antiviral drug Riamilovir (“Triazavirin®”) active against SARS-CoV-2 (COVID-19)Review article Published on 2022-01-262022-10-05 Journal: Organic & Biomolecular Chemistry [Category] 치료제, [키워드] active against antiviral drug approach biological activities Compound COVID-19 derivative fragment information Riamilovir SARS-CoV-2 Structure synthetic [DOI] 10.1039/d1ob02125g [Article Type] Review article
Insights Into Amentoflavone: A Natural Multifunctional BiflavonoidPharmacology Published on 2021-12-222022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] activity addition amentoflavone anti-cancer Anti-inflammatory anti-SARS-CoV-2 Biflavonoid binding Bioavailability biological activities biological activity cancers drug delivery ERK Extracellular in silico Approach insight metabolism molecular docking molecular mechanism molecular target multifunctional Musculoskeletal natural NF-κB nuclear protease RBD RdRP Receptor binding domain recorded Regulation Research RNA-dependent RNA polymerase SARS-CoV-2 Selaginella tamariscina signaling pathway Spike protein therapeutic [DOI] 10.3389/fphar.2021.768708 PMC 바로가기 [Article Type] Pharmacology