Evaluation of the Relationship Between Aquaporin-1, Hepcidin, Zinc, Copper, and İron Levels and Oxidative Stress in the Serum of Critically Ill Patients with COVID-19Article Published on 2022-12-012022-11-16 Journal: Biological trace element research [Category] COVID19(2023년), SARS, 치료기술, [키워드] antioxidant aquaporin both groups chronic disease control group copper correlation COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients determine disease severity elements Endotracheal intubation had no healthy hepcidin Ill in viral indicated individual Infection Inpatient intensive care Invasive mechanical ventilation Level negative PCR test oxidative stress parameter patients with COVID-19 relationship Result SARS-CoV-2 separated sera Significant statistically significant TAC the healthy the patient Total Total antioxidant status Total oxidant status trace Trace element trace elements two groups with COVID-19 Zinc [DOI] 10.1007/s12011-022-03400-6 PMC 바로가기
SARS-CoV-2 quasi-species analysis from patients with persistent nasopharyngeal sheddingArticle Published on 2022-11-042022-11-16 Journal: Scientific Reports [Category] SARS, 변종, [키워드] Analysis asked both groups clade Consequences Control COVID 19 deviation Evolution of SARS-CoV-2 genomic greater Human immune system immune evasion increase Infectious virus Interaction intra-individual investigated Mutation N501Y nasopharyngeal no significant difference P681H pandemic Patient patients performed persistence Prevent question RNA virus SARS-CoV-2 Sequencing Standard survival the SARS-CoV-2 therapeutic two group Variability variants viral propagation viral variant [DOI] 10.1038/s41598-022-22060-z PMC 바로가기
IgG-RBD Response Due to Inactivated SARS-CoV-2 Vaccine: Alteration in D-Dimer and Fibrinogen Concentrations, Association with Comorbidities and Adverse EffectsArticle Published on 2022-11-032022-11-15 Journal: Laboratory medicine [Category] SARS, 진단, [키워드] Adverse alteration appear blood sample both groups changes in Concentration CoronaVac Coronavirus infection COVID-19 COVID-19 infection D-dimer D-dimer level domain Effect effective fibrinogen fibrinogen level first vaccination IgG Immunoglobulin individual infected individual Infection Mask Measures Participants Protective response Safe SARS-CoV-2 second dose second vaccination Side effects significantly higher statistically subject vaccination Vaccine was obtained were measured [DOI] 10.1093/labmed/lmac047 PMC 바로가기
Immunogenicity and efficacy of COVID-19 vaccines in people living with HIV: a systematic review and meta-analysisArticle Published on 2022-11-012022-11-15 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 진단, [키워드] affected Antibody titer booster vaccination both groups Cochrane Library comparable COVID-19 COVID-19 vaccine COVID-19 vaccines effective Efficacy healthy controls healthy individuals HIV immunogenicity IMPROVE in healthy individuals inclusion criteria increased risk less Messenger RNA Meta-analysis participant patients PLWH random-effect reduced risk ratio SARS-CoV-2 SARS-CoV-2 antibody searched second dose Seroconversion severe COVID-19 significantly subject systematic review vaccination vaccine dose was performed with HIV [DOI] 10.1016/j.ijid.2022.10.005 PMC 바로가기
SARS-CoV-2 Omicron BA.1 variant breakthrough infections in nursing home residents after an homologous third dose of the Comirnaty® COVID-19 vaccine: Looking for correlates of protectionComirnaty® COVID-19 백신의 동종 3차 접종 후 요양원 거주자의 SARS-CoV-2 Omicron BA.1 변이형 돌발성 감염: 보호 상관 관계 찾기Observational Study Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술, 치료제, [키워드] anti-RBD Anti-spike anti-spike antibodies antibody blood levels booster dose both groups Breakthrough infection CD4 CD8 chemiluminescent immunoassay Comirnaty® COVID-19 vaccine comparable COVID-19 COVID-19 vaccine cytokine detectable dose evaluated female flow cytometry Frequency homologous immune parameter Immunological response in both groups individual level Infection intracellular cytokine staining investigated likelihood median median age Neutralization assay Neutralizing Neutralizing antibodies neutralizing antibody not correlated nursing home nursing home residents observational study omicron Omicron variant participant Peripheral blood predict Pseudotyped virus quantified reactive Receptor binding domain risk SARS-CoV-2 SARS-CoV-2 Omicron variant SARS-CoV-2 spike SARS-CoV-2-S spike spike-reactive T cells. subsequent symptomatic T cell T cells total antibody uninfected participant Vaccine variant were measured [DOI] 10.1002/jmv.27867 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2-specific antibodies and neutralization capacity in breast milk following infection vs vaccinationArticle Published on 2022-09-012022-11-15 Journal: Ultrasound in obstetrics & gynecology : the offici [Category] SARS, 진단, [키워드] acute respiratory syndrome anti-SARS-CoV-2 antibody antibody binding booster dose both groups breast milk changes in children collected convenience sampling coronavirus coronavirus disease COVID-19 COVID-19 vaccine evaluate first dose Gynecology highlight IgA IgA level immunoglobulin A individuals Infection median natural infection neutralization capacity Neutralizing neutralizing antibody peaking Prospective Study rapid increase receive recruited restored SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibody secretion Society stimulated study groups the median the vaccine Ultrasound undetectable vaccination Vaccine women [DOI] 10.1002/uog.24965 PMC 바로가기
The effects of high dose vitamin D supplementation as a nutritional intervention strategy on biochemical and inflammatory factors in adults with COVID-19: Study protocol for a randomized controlled trialCOVID-19 성인의 생화학적 및 염증 인자에 대한 영양 중재 전략으로서 고용량 비타민 D 보충제의 효과: 무작위 대조 시험을 위한 연구 프로토콜Article Published on 2022-09-012022-09-11 Journal: Nutrition and health [Category] 바이오마커, 임상, [키워드] All participant All participants Analysis baseline biochemical blood count both groups CBC changes in chest CT scan classification clinical outcomes complete blood count conducted confounders control group covariance COVID-19 Descriptive statistics diagnosis of COVID-19 double-blind duration of hospitalization Effect erythrocyte sedimentation erythrocyte sedimentation rate ESR Evidence followed by gel heart High dose hospitalized COVID-19 patients hs-CRP Imam in both groups Inflammation Inflammatory factor Inflammatory marker inflammatory markers intervention group Iran Laboratory life liver Mashhad mortality rate New York nutritional intervention parameter participant Patient performed Placebo protocol Quality of life randomization Randomized Randomized controlled trial receive recorded renal Reza risk factor RT-PCR sedimentation rate serum serum vitamin D shown study period Trial undergo Vitamin D Vitamin D supplementation with COVID-19 [DOI] 10.1177/02601060221082384 PMC 바로가기 [Article Type] Article
Plasma microRNA and metabolic changes associated with pediatric acute respiratory distress syndrome: a prospective cohort study Research Published on 2022-08-262022-10-05 Journal: Scientific Reports [Category] 바이오마커, [키워드] acute respiratory distress ARDS Bacterial infection Biomarker Biomarkers both groups change circulating circulation Clinical characteristics conducted control patient correlated Critically ill defined differential expression differentially expressed distress evaluate heterogeneous identify intensive care patients metabolite metabolomics microRNA MicroRNAs miRNA miRNA expression morbidity and mortality non-coding RNA pathophysiological Patient pediatric Pediatric patient Pediatric patients pilot study prognostic biomarker progression prospective cohort study provide Random forest random forest classification responsible risk selected single-center sub-cohort subset syndrome therapeutic intervention [DOI] 10.1038/s41598-022-15476-0 [Article Type] Research
BNT162b2-boosted immune responses six months after heterologous or homologous ChAdOx1nCoV-19/BNT162b2 vaccination against COVID-19COVID-19에 대한 이종 또는 동종 ChAdOx1nCoV-19/BNT162b2 백신 접종 후 6개월 후 BNT162b2로 강화된 면역 반응Article Published on 2022-08-182022-09-11 Journal: Nature Communications [Category] SARS, 변종, 임상, 진단, 치료기술, 치료법, [키워드] Alpha anti-Spike IgG approach B.1.1.529 Beta BNT BNT162b2 both groups CD4 CD8 Cell ChAd choice compensated delta variant Delta variants Effect followed by Frequency Gamma Heterologous homologous immune response immune responses Immunity in both groups increase in moderate mRNA vaccine Neutralizing activity Neutralizing antibody response neutralizing antibody responses omicron protective immunity repeated reported SARS-CoV-2 second vaccination subsequent T cell vaccinated individual vaccinated individuals vaccination vaccination against COVID-19 Vaccine variant virus [DOI] 10.1038/s41467-022-32527-2 PMC 바로가기 [Article Type] Article
Screening and assessment for post-acute COVID-19 syndrome (PACS), guidance by personal pilots and support with individual digital trainings within intersectoral care: a study protocol of a randomized controlled trial급성 COVID-19 이후 증후군(PACS)에 대한 선별 및 평가, 개인 파일럿의 지도 및 부문 간 치료 내 개별 디지털 교육 지원: 무작위 대조 시험의 연구 프로토콜Article Published on 2022-08-152022-09-11 Journal: BMC Infectious Diseases [Category] SARS, 임상, [키워드] active control group activities activity applicability assigned both group both groups can be used Care chatbot comparability COVID-19 COVID-19 infection Cross-sectoral care Diagnosis Digital Digital therapy offers empowerment Endpoint evaluate evaluated example facilitate feasibility Guidance help helping Identifier IMPROVE Interdisciplinary diagnostic International Intervention intervention group long-COVID Low-threshold screening Medical rehabilitation outcome participant Participants Patient physiological platform Post-acute COVID-19 syndrome Post-COVID primary endpoints propensity score matching Psychological Randomized controlled trial Randomly receive recruited reduce reduction Registration Research return screened Screening secondary Secondary outcomes Study protocol Support supported Symptom Symptom assessment Symptoms syndrome therapy Treatment Trial registration [DOI] 10.1186/s12879-022-07584-z PMC 바로가기 [Article Type] Article