breathlessness – Communicable Diseases Research

Enhancing COVID Rehabilitation with Technology (ECORT): protocol for an open-label, single-site randomized controlled trial evaluating the effectiveness of electronic case management for individuals with persistent COVID-19 symptoms

Article

Published on 2022-09-022022-10-04
Journal: Trials [Category] SARS, 임상, 치료제,

An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms following COVID-19: a parallel-group, single-blind, randomised controlled trial

Randomized Controlled Trial

Published on 2022-09-012022-10-04
Journal: The Lancet. Respiratory Medicine [Category] Fulltext, MERS, 임상,

[키워드] 1:1 adverse event Analysis Anxiety approach approaches assigned Block randomisation breathlessness chronic obstructive clinically clinics complementary computer-generated conducted COVID COVID-19 eight element English Generalised anxiety disorder groups Health Imperial College London IMPROVE improvement individual intention-to-treat population Intervention Mental mental health MHC outcome measure parallel-group participant participated Patient physical potential participant Primary outcome pulmonary disease qualitative data randomisation randomised controlled trial Randomly recovering from COVID-19 recruited Registered reported Research researcher responses responsible secondary secondary outcome single-blind statistically significant Symptom thematic analysis treatment group Trial unique usual care usual care group Visual Analogue Scale was done were excluded were given
[DOI] 10.1016/S2213-2600(22)00125-4 PMC 바로가기 [Article Type] Randomized Controlled Trial

Prevention and early treatment of the long-term physical effects of COVID-19 in adults: design of a randomised controlled trial of resistance exercise-CISCO-21

Randomized Controlled Trial

Published on 2022-08-152022-10-05
Journal: Trials [Category] SARS, 임상,

[키워드] Admission breathlessness cause chest pain Contact Controlled clinical trial COVID COVID-19 COVID-19 infection diagnosis of COVID-19 discharged Dyspnoea early treatment Effect Ethical approval ethics committee Exercise capacity fatigue frailty group Health Health status healthcare professionals hospital hospitalisation hospitalised Infection Intervention Long Long COVID National Health Service NHS participant Patient personalised physical physical activity Pragmatic prevention Primary outcome problem Quality of life questionnaire randomisation randomised randomised controlled trial REC recruitment Registered rehabilitation resistance resistance exercise SARS-CoV-2 secondary outcome spirometry Symptom syndrome therapy Two-arm usual care West
[DOI] 10.1186/s13063-022-06632-y PMC 바로가기 [Article Type] Randomized Controlled Trial

Long-term functioning status of COVID-19 survivors: a prospective observational evaluation of a cohort of patients surviving hospitalisation

Observational Study

Published on 2022-07-272022-10-04
Journal: BMJ Open [Category] COVID19(2023년), SARS, 임상,

[키워드] 24 hour activities acute SARS-CoV-2 infection age analogue Analysis Anxiety assessment Borg Brazil breathlessness Care chronic clinical manifestations cohort of patient COVID-19 daytime Depression disability fatigue functional Functional status handgrip strength hospital hospital discharge hospitalisation hospitalised illness Independence indicated Insomnia Insomnia Severity Index intake Invasive mechanical ventilation investigated Long-term condition measure Medical Research Council MOST MRC muscle oral Pain participant prevalent prospective observational study public health reduced rehabilitation medicine reported required scale schedule sleepiness Sociodemographic Stand strength survivor Survivors Test treat university hospital Visual weakness WHO
[DOI] 10.1136/bmjopen-2021-057246 PMC 바로가기 [Article Type] Observational Study

Exploring the Immunomodulatory Aspect of Mesenchymal Stem Cells for Treatment of Severe Coronavirus Disease 19

중증 코로나바이러스 질환 치료를 위한 중간엽 줄기세포의 면역조절 측면 탐색 19

Review

Published on 2022-07-122022-09-11
Journal: Cells [Category] COVID19(2023년), SARS, 치료법,

[키워드] ACE-2 acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 acute respiratory syndrome coronavirus-2 administration affected Alpha alveolar epithelial cell alveolar epithelial cells angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 anti-apoptotic Anti-inflammatory anti-oxidative aspect Asymptomatic average Betacoronavirus breathlessness cause cellular characterized chemokines chest pain Clinical outcome Clinical symptoms colony-stimulating factor coronavirus 2 COVID-19 COVID-19 patient Critically ill critically ill COVID-19 patients curative cytokine Cytokine storm Cytokine storms damaged dependent on Deterioration disease severity dry cough Effectiveness Effects elicited endothelial engage enzyme epithelial cells excessive inflammation family Coronaviridae fatigue Fever fibroblast fibroblast growth factor functional GCSF genus genus Betacoronavirus granulocyte granulocyte colony-stimulating factor growth factor Growth factors Health healthy histological IL-6 IL-7 IL-8 IL-9 immune cells immune response immune responses immunomodulation immunomodulatory immunomodulatory capabilities immunomodulatory capability Incubation period individual infected individual infected individuals infiltrating immune cells Inflammatory Inflammatory cytokines inflammatory protein inhalation Injury Intention interferon interleukin intravenous intravenous infusion Invasion IP10 lung Lungs Macrophage majority MCP1 Mesenchymal stem cells MIP1A mitigate monocyte monocyte chemotactic protein-1 MSC MSCs multitude myriad Necrosis organ PDGFB persistence Platelet platelet-derived growth factor positioned positive Protein receptor reduce respiratory Respiratory droplets RNA SARS-CoV-2 SARS-COV-2 infection secretion Secretome Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 sore throat STEM stem cell stem cells subunit supportive therapy symptomatic therapeutic therapy tissue TNF-α translational transmitted Treatment Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha undergo Vascular virus widespread
[DOI] 10.3390/cells11142175 PMC 바로가기 [Article Type] Review

Ftl-CoV19: A Transfer Learning Approach to Detect COVID-19

Ftl-CoV19: COVID-19 감지를 위한 전이 학습 접근 방식

Article

Published on 2022-07-052022-09-11
Journal: Computational Intelligence and Neuroscience [Category] Coronavirus, COVID19(2023년), SARS, 치료기술,

A case report of moderate COVID 19 patient managed through integrative approach (Siddha and conventional medicine)

Case report

Published on 2022-07-012022-10-05
Journal: Journal of Ayurveda and Integrative Medicine [Category] 바이오마커, 치료제,

Anti-inflammatory response of cardamom extract and prediction of therapeutic window in COVID-19 patients by assessing inflammatory markers using RT-PCR

RT-PCR을 사용한 염증 마커를 평가함으로써 COVID-19 환자에서 카 다몬 추출물의 항 염증 반응 및 치료 창의 예측

Article

Published on 2022-06-012022-08-31
Journal: Inflammopharmacology [Category] COVID19(2023년), MERS, SARS, 진단, 치료제,

[키워드] addition alternative Anti-inflammatory anti-inflammatory action anti-inflammatory response Anti-viral association attending physician Awareness breathlessness can not Cardamom Clinical improvement Clinical practice clinician control group cough Course COVID-19 COVID-19 patient COVID-19 patients COVID-19 symptom COVID-19 symptoms CRP Ct values cycle threshold cytokine Cytokine storm dawn Diagnostic method diagnostic test diagnostic tests disease Disease progression dosage dose effective elevated end point enrolled Fever FORTE gene expression profile hospital IL-10 IL-6 India indicate Inflammation Inflammatory marker inflammatory markers inflammatory parameter intake Intervention lack LDH majority material molecular diagnostics morbidity morbidity and mortality multiplex negativity normalized onset of symptom outcome parameter Patient patients PCR test performed popularity potentiality predict Prednisolone prevalent Prognosis protein level provide reason for reducing reported RT-PCR RT-PCR analysis RT-PCR assay RT-PCR test SARS-CoV-2 SARS-CoV-2 RT-PCR SARS-CoV-2 RT-PCR test serum Serum IL-6 sore throat Standard of care standard treatment Steroids Symptom Tablet tested the cytokine storm the patient therapeutic window time TNF- α Treatment treatment arm treatment group were given worsening
[DOI] 10.1007/s10787-022-00951-x PMC 바로가기 [Article Type] Article

A novel epidemiological scoring system for the prediction of mortality in COVID-19 patients

COVID-19 환자의 사망률 예측을 위한 새로운 역학 채점 시스템

Article

Published on 2022-05-022022-09-11
Journal: Transactions of the Royal Society of Tropical Medi [Category] COVID19(2023년), SARS, 치료기술,

[키워드] Accuracy Admission age AUROC breathlessness characteristic clinical symptom Clinical symptoms co-morbidities Cohort Comorbidities Comorbidity coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 patient COVID-19 patients COVID-19 scoring system CSS develop diabete diabetes diagnostic Diagnostic accuracy early prediction of mortality early stage epidemiological group higher risk hospital independent risk factor indicate inflammatory markers Mann Whitney U Test medium morbidities Mortality MOST patient age positive positive relationship predicted proportion receiver operating characteristic receiver operating characteristic curve reported risk Risk factors Scoring Scoring and validation cohort scoring system Sensitivity and specificity severe COVID-19 patients Treatment Triage validation cohort were used
[DOI] 10.1093/trstmh/trab108 PMC 바로가기 [Article Type] Article

CT Lung Abnormalities after COVID-19 at 3 Months and 1 Year after Hospital Discharge

Observational Study

Published on 2022-05-012022-10-05
Journal: Radiology [Category] Fulltext, MERS, 임상,