Voclosporin and the Antiviral Effect Against SARS-CoV-2 in Immunocompromised Kidney PatientsClinical Research Published on 2023-09-072024-09-05 Journal: Kidney International Reports [Category] update2024, [키워드] calcineurin inhibitors COVID-19 Kidney transplantation lupus erythematosus lupus nephritis SARS-CoV-2 [DOI] 10.1016/j.ekir.2023.09.003 PMC 바로가기 [Article Type] Clinical Research
Hepatitis E prevalence and infection in solid-organ transplant recipients in the United StatesMulticenter Study Published on 2022-12-012023-06-12 Journal: Journal of viral hepatitis [Category] E형 간염, [키워드] calcineurin inhibitors graft hepatitis HEV Viral hepatitis Viremia [DOI] 10.1111/jvh.13739 [Article Type] Multicenter Study
Cardiovascular Risk Following Conversion to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: A Randomized Clinical Trialarticle Published on 2022-11-182024-09-02 Journal: Kidney Medicine [Category] 대상포진, [키워드] Arterial stiffness belatacept blood pressure calcineurin inhibitors cardiovascular disease Kidney transplantation Mortality pulse wave velocity randomized clinical trial tacrolimus [DOI] 10.1016/j.xkme.2022.100574 PMC 바로가기 [Article Type] article
Ongoing Mycophenolate Treatment Impairs Anti-SARS-CoV-2 Vaccination Response in Patients Affected by Chronic Inflammatory Autoimmune Diseases or Liver Transplantation Recipients: Results of the RIVALSA Prospective Cohort진행중인 미코페놀레이트 치료는 만성 염증성 자가면역 질환 또는 간 이식 수혜자의 영향을 받는 환자에서 항-SARS-CoV-2 백신 반응을 손상시킵니다: RIVALSA 예상 코호트의 결과Observational Study Published on 2022-08-122022-09-11 Journal: Viruses [Category] SARS, 임상, 진단, 치료기술, [키워드] 95% CI administration Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 vaccination Antibody Response Antibody titers ARMS Arthritis Autoimmune Autoimmune disease Autoimmune diseases Autoimmune hepatitis calcineurin calcineurin inhibitors chronic cohort of patients Complete connective tissue disease Connective tissue diseases detectable develop Diagnosis dose dose reduction Effect effective Eligible patients enrolled evaluate evaluated example first dose healthy subjects hepatology identify IgG immunogenicity immunosuppressive immunosuppressive therapy Immunosuppressive treatment independent predictor independent predictors individual inhibitor liver liver transplant Liver transplantation MMF mRNA COVID-19 vaccine mRNA COVID-19 vaccines mRNA vaccine mRNA-based Multivariate analysis mycophenolate mycophenolate. neoplasia Novara observational study organ other diseases overlapped Patient patients performed predictor Prevent Prospective prospective observational study receiving recipients rejection required response Result rheumatoid arthritis rheumatological SARS-COV-2 infection selected Seroconversion seroconversion failure spondyloarthritis subgroups of patient suffered Suspension Tertiary therapy transplantation transplants treated Treatment unit Univariate analysis university vaccinated individual vaccination Vaccine vaccine response Vasculitis [DOI] 10.3390/v14081766 PMC 바로가기 [Article Type] Observational Study
Impaired antigen-specific B-cell responses after Influenza vaccination in kidney transplant recipients receiving co-stimulation blockade with BelataceptArticle Published on 2022-07-292023-06-14 Journal: Frontiers in Immunology [Category] Fulltext, 신종인플루엔자, [키워드] calcineurin inhibitors co-stimulation blockade influenza vaccination Kidney transplantation memory B cells T follicular helper (Tfh) cell [DOI] 10.3389/fimmu.2022.918887 PMC 바로가기
The Cyclophilin-Dependent Calcineurin Inhibitor Voclosporin Inhibits SARS-CoV-2 Replication in Cell Culture사이클로필린 의존성 칼시뉴린 억제제 보클로스포린은 세포 배양에서 SARS-CoV-2 복제를 억제합니다Article Published on 2022-06-242022-09-11 Journal: Transplant International [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral activity Antiviral assays assays benefit binding calcineurin calcineurin inhibitors can not clinical evaluation CNI Combination Comorbidity Compound compounds Concentration coronavirus Coronaviruses Course COVID-19 cyclophilin cyclosporin cyclosporin A EC50 value EC50 values evaluated experiments False-positive results human Calu-3 cell human Calu-3 cells Immunosuppressant immunosuppressants Immunosuppression immunosuppressive increased risk Infection inhibitor Interference kidney kidney transplant recipients Kidney transplantation lab progeny protocol recipient reduced reducing regimen reported RNA viruses SARS-CoV-2 SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus tacrolimus voclosporin voclosporin. with COVID-19 [DOI] 10.3389/ti.2022.10369 PMC 바로가기 [Article Type] Article
Conversion from Calcineurin Inhibitor– to Belatacept-Based Maintenance Immunosuppression in Renal Transplant Recipients: A Randomized Phase 3b TrialClinical Research Published on 2021-12-012024-09-04 Journal: Journal of the American Society of Nephrology [Category] 대상포진, [키워드] abatacept acute rejection calcineurin inhibitors Immunosuppression Kidney transplantation Randomized controlled trials renal function Renal transplantation Transplant recipients [DOI] 10.1681/ASN.2021050628 PMC 바로가기 [Article Type] Clinical Research
Old and New Calcineurin Inhibitors in Lupus NephritisReview Published on 2021-10-212024-09-02 Journal: Journal of Clinical Medicine [Category] 대상포진, [키워드] calcineurin inhibitors cyclosporine lupus nephritis Proteinuria tacrolimus voclosporin [DOI] 10.3390/jcm10214832 PMC 바로가기 [Article Type] Review
Combined Therapy of Ciclosporin Plus Favipiravir in the Management of Patients with Severe COVID-19, not Responding to Dexamethasone: A non-Controlled Prospective Trial덱사메타손에 반응하지 않는 중증 COVID-19 환자 관리에서 시클로스포린과 파비피라비르의 병용 요법: 비대조 전향적 시험Clinical Trial Published on 2021-10-012022-09-11 Journal: International immunopharmacology [Category] SARS, 임상, 치료제, [키워드] Antiviral calcineurin calcineurin inhibitors calculated carried characterized Ciclosporin clinical trial Combination Combined Confirmed COVID-19 patient confirmed COVID-19 patients Controlled controlled trials COVID-19 COVID-19 pandemic COVID-19 patient Dexamethasone dose Efficacy evaluate evaluated Favipiravir favorable effect ferritin Hospital stay ICU ICU admission immunomodulatory effects inhibitor Injections intensive care intensive care unit lung mechanical ventilation mortality rate Patient patients potential therapeutic agent potential therapeutic agents Prospective protocol respond Responding SARS-CoV-2 second dose significantly higher therapy Trial were assessed White blood cell White blood cells [DOI] 10.1016/j.intimp.2021.108043 PMC 바로가기 [Article Type] Clinical Trial
Can acute respiratory distress syndrome be treated?Editorial Published on 2021-03-162023-06-13 Journal: Future Medicinal Chemistry [Category] MERS, [키워드] ARDS calcineurin inhibitors COVID-19 peptidyl drugs [DOI] 10.4155/fmc-2021-0014 PMC 바로가기 [Article Type] Editorial