A Two-Stage Transferred Cold Atmospheric Plasma as a Unique Therapeutic Strategy for Targeting Colon Cancer Stem CellsOriginal Article Published on 2024-07-202024-09-05 Journal: Advanced Pharmaceutical Bulletin [Category] update2024, [키워드] Apoptosis Cancer cells Colon cancer stem cells Two-stage transferred cold atmospheric plasma [DOI] 10.34172/apb.2024.041 PMC 바로가기 [Article Type] Original Article
Recent Progress in Organic Electrochemical Transistor-Structured BiosensorsReview Published on 2024-07-042024-09-05 Journal: Biosensors [Category] update2024, [키워드] biosensors Cancer cells electro-inactive electroactive organic electrochemical transistors sensing systems wearable and implantable applications [DOI] 10.3390/bios14070330 PMC 바로가기 [Article Type] Review
Macromolecule–Nanoparticle-Based Hybrid Materials for Biosensor ApplicationsReview Published on 2024-05-282024-09-05 Journal: Biosensors [Category] update2024, [키워드] amino acids biomolecules biosensor Cancer cells cholesterol Dopamine Glucose hydrogen peroxide limit of detection Limit of quantification Macrocycles macromolecules sensitivity uric acid [DOI] 10.3390/bios14060277 PMC 바로가기 [Article Type] Review
Structural interactions of phytoconstituent(s) from cinnamon, bay leaf, oregano, and parsley with SARS-CoV-2 nucleocapsid protein: A comparative assessment for development of potential antiviral nutraceuticalsArticle Published on 2022-10-012022-11-15 Journal: Journal of food biochemistry [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] affinity Antiviral antiviral agent apigenin binding binding domain binding interaction biological activity C-terminal Cancer Cancer cells candidate carried cell line cell lines cells Cinnamomum cinnamon complex complexes components Compound computational analysis computational approach CTD cytotoxicity death drug candidate Druglikeness effective Efficacy evaluate evaluated examined greater HPLC in silico in vitro in vivo Interaction lack less molecular molecular dynamics MTT N-terminal Naturally NTD nucleocapsid nutraceutical oregano Origanum outcome parsley. plant predicted profile Prophylactic Protein provided Research responsible RNA SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 nucleocapsid protein stability symptomatic targets therapeutic therapeutic drug therapy Toxicity treating COVID-19 Treatment virus was determined was performed worsened [DOI] 10.1111/jfbc.14262 PMC 바로가기
Antimicrobial peptides: features, applications and the potential use against covid-19Article Published on 2022-10-012022-11-16 Journal: Molecular biology reports [Category] 변종, [키워드] accelerated addition AMP AMPs Antibiotics antimicrobial antimicrobial peptides APD Bacteria biosynthesis pathway Cancer cells cationic clinical trial conserved COVID-19 demonstrated develop drugs Evolution Features functional fungi Innate immunity mechanism mechanisms peptide provide specificity therapeutic therapeutic agents Toxicity unique variants viral infectivity viruses [DOI] 10.1007/s11033-022-07572-1 PMC 바로가기
A new-type HOCl-activatable fluorescent probe and its applications in water environment and biosystems새로운 유형의 HOCl 활성화 가능한 형광 프로브 및 물 환경 및 생물 시스템에서의 응용Article Published on 2022-09-152022-09-11 Journal: The Science of the total environment [Category] 치료기술, 치료제, [키워드] Accuracy Affect aggregate assistance Biotin biotinylated Cancer cancer cell Cancer cells cancer diagnosis Cell cells chlorine Concentration Consumption contribute convenience Corona COVID-19 Early Cancer expected Fluorescence fluorescent Fluorescent probe Health HOCl human body hypochlorite hypochlorous acid inflammatory disease Inflammatory diseases introduced kill membrane outbreak overexpressed oxygen PBS Precision probe reactive oxygen specy receptor ROS significant increase sodium sodium hypochlorite Spread Virus Disease viruses water Water samples. while [DOI] 10.1016/j.scitotenv.2022.156164 PMC 바로가기 [Article Type] Article
Cancer vaccines: Building a bridge over troubled watersReview article Published on 2022-07-132022-10-05 Journal: Cell [Category] 비임상, [키워드] Antigen approaches building Cancer Cancer cells help highlight immune system Mouse models natural immunity post-vaccination responses recent single-cell unique Vaccine [DOI] 10.1016/j.cell.2022.06.035 [Article Type] Review article
Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer응급실 스트레스 상태의 급성기에 대응하기 위해 항혈소판제 티클로피딘의 용도 변경: 코로나바이러스 감염 및 암 퇴치를 위한 기회Article Published on 2022-07-062022-09-11 Journal: Molecules [Category] COVID19(2023년), SARS, 신약개발, [키워드] Achille agent antiplatelet Antiplatelet agent approach approved drugs attribute Cancer Cancer cells Cell Coronavirus infections Coronavirus-2 COVID-19 demonstrated Endoplasmic reticulum endoplasmic reticulum (ER) ER membranes ER stress exacerbating Fighting heel homeostasis life cycle Metastasis Modification modulation opportunity P2Y12 P2Y12 inhibitors pathological conditions Perturbation phase promote receptor representing repurposing responsible SARS Coronavirus SARS-CoV-2 sigma sigma 1 receptor (S1R) terminal UPR the disease therapeutic intervention Therapies ticlopidine ticlopidine. Tumor tumor growth unfolded protein response UPR viral glycoprotein viral glycoproteins viral infection viral infections viral life cycle [DOI] 10.3390/molecules27144327 PMC 바로가기 [Article Type] Article
Saquinavir: From HIV to COVID-19 and Cancer Treatment사퀴나비르: HIV에서 COVID-19 및 암 치료까지Review Published on 2022-07-052022-09-11 Journal: Biomolecules [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] 3CLpro anticancer antivirals Apoptosis approval approved drug Cancer Cancer cells cancer treatment Cell changed clinical trial clinical trials Combination COVID-19 COVID-19 outbreak cytotoxicity disease drug Drug repurposing Effect Follow-up help HIV impede in silico in vitro in vivo increased survival Invasion lack mind Neuroblastoma pathway pharmacological promise protease Protease inhibitor Research saquinavir saquinavir. SARS-CoV-2 main protease shown tested the SARS-CoV-2 therapy translated Treatment virus [DOI] 10.3390/biom12070944 PMC 바로가기 [Article Type] Review
Interference of Chaga mushroom terpenoids with the attachment of SARS-CoV-2; in silico perspectiveSARS-CoV-2의 부착으로 차가버섯 테르페노이드의 간섭; 실리코 관점에서Article Published on 2022-06-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 변종, 신약개발, [키워드] 501.V2 affinities approach binding affinities binding affinity binding energy can be used cancer cell Cancer cells Chaga terpenoids compounds COVID-19 domain drug finding Glucose GRP78 host cell host cell receptor HSPA5 in silico in vivo in-silico inhibitor interfere Interference investigator MM-GBSA molecular docking molecular dynamics Molecular dynamics simulation molecular dynamics simulations NAMD pandemic peptide performed Perspective Protein receptor receptors Recognition reported Result SARS-CoV-2 SARS-CoV-2 receptor targeting terpenoid tested the binding affinity the SARS-CoV-2 therapeutic variants variants of SARS-CoV-2 was tested [DOI] 10.1016/j.compbiomed.2022.105478 PMC 바로가기 [Article Type] Article